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gtfB gtfB gtfC gtfC wapE wapE srtA srtA gbpC gbpC SMU_1432c SMU_1432c sacB sacB dexA dexA gbpA gbpA gbpB gbpB spaP spaP alaS alaS gbpD gbpD SMU_833 SMU_833 gtfD gtfD wapA wapA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gtfBglucosyltransferase-I; Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris; Belongs to the glycosyl hydrolase 70 family. (1476 aa)
gtfCglucosyltransferase-SI; Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris; Belongs to the glycosyl hydrolase 70 family. (1455 aa)
wapEHypothetical protein; Best Blastp Hit: gi|6324372 anchorage subunit of a-agglutinin; Aga1p [Saccharomyces cerevisiae] >gi|416592|sp|P32323|AGA1_YEAST A-AGGLUTININ ATTACHMENT SUBUNIT PRECURSOR >gi|101170|pir||A41258 a-agglutinin core protein AGA1 - yeast (Saccharomyces cerevisiae) >gi|170964|gb|AAA34382.1| (M60590) a-agglutinin core subunit [Saccharomyces cerevisiae] >gi|1302552|emb|CAA96325.1| (Z71659) ORF YNR044w [Saccharomyces cerevisiae]. (507 aa)
srtAPutative sortase; Best Blastp Hit: gb|AAA73122.1| (M77279) alpha-amylase [unidentified cloning vector]. (246 aa)
gbpCGlucan-binding protein C, GbpC; Best Blastp Hit: dbj|BAA12713.1| (D85031) glucan-binding protein C [Streptococcus mutans]. (583 aa)
SMU_1432cPutative endoglucanase precursor; Best Blastp Hit: sp|P19254|GUB_BACCI BETA-GLUCANASE PRECURSOR (ENDO-BETA-1,3-1,4 GLUCANASE) >gi|98112|pir||S10485 licheninase (EC 3.2.1.73) - Bacillus circulans >gi|39416|emb|CAA37062.1| (X52880) lichenase (AA 1-409) [Bacillus circulans]; Belongs to the glycosyl hydrolase 8 (cellulase D) family. (295 aa)
sacBLevansucrase precursor; Best Blastp Hit: sp|P11701|SACB_STRMU LEVANSUCRASE## PRECURSOR (BETA-D-FRUCTOFURANOSYL TRANSFERASE) (SUCROSE 6-FRUCTOSYL TRANSFERASE) >gi|79999|pir||B28551 levansucrase (EC 2.4.1.10) precursor - Streptococcus mutans (strain GS-5) >gi|153636|gb|AAA88584.1| (M18954) fructosyltransferase [Streptococcus mutans]; Belongs to the glycosyl hydrolase 68 family. (795 aa)
dexADextranase precursor; May play a role in sucrose-independent adherence to the pellicle-coated tooth surface; Belongs to the glycosyl hydrolase 66 family. (850 aa)
gbpABest Blastp Hit: pir||A37184 glucan-binding protein - Streptococcus mutans >gi|153638|gb|AAA26894.1| (M30945) glucan-binding protein (gbp) [Streptococcus mutans]. (565 aa)
gbpBBest Blastp Hit: gb|AAD00288.1| (U78607) putative secreted protein [Streptococcus mutans]. (431 aa)
spaPCell surface antigen SpaP; Surface protein antigen implicated in dental caries; Belongs to the SpaP/Ssp5/SpaA family. (1562 aa)
alaSPutative alanyl-tRNA synthetase (alanine--tRNA ligase); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (872 aa)
gbpDGlucan-binding protein D with lipase activity; Best Blastp Hit: gb|AAF89976.1|AF206272_2 (AF206272) BglB [Streptococcus mutans]. (726 aa)
SMU_833Putative glycosyltransferase; Best Blastp Hit: sp|Q45539|CSBB_BACSU CSBB PROTEIN >gi|2126920|pir||JC5173 stress response protein csbB - Bacillus subtilis >gi|1387979|gb|AAB38429.1| (L77099) 44% identity over 302 residues with hypothetical protein from Synechocystis sp, accession D64006_CD; expression induced by environmental stress; some similarity to glycosyl transferases; two potential membrane-spanning helices [Bacillus subtil> >gi|2633183|emb|CAB12688.1| (Z99108) stress response protein [Bacillus subtilis] >gi|2804544|dbj|BAA24480.1| (D85082) YfhN [Bacillus subtilis]. (308 aa)
gtfDglucosyltransferase-S; Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris; Belongs to the glycosyl hydrolase 70 family. (1462 aa)
wapABest Blastp Hit: sp|P11000|WAPA_STRMU WALL-ASSOCIATED PROTEIN PRECURSOR >gi|98001|pir||S06992 wall-associated protein A precursor - Streptococcus mutans >gi|153858|gb|AAA88608.1| (M37842) wall-associated protein [Streptococcus mutans]. (453 aa)
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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