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SMU_1043c SMU_1043c krpS krpS ldh ldh pykF pykF pfk pfk deoB deoB rpiA rpiA eno eno adhA adhA adhB adhB adhC adhC adhD adhD SMU_1309c SMU_1309c lplA lplA pdhC pdhC pdhB pdhB pdhA pdhA pdhD pdhD SMU_1657c SMU_1657c nrgA nrgA pflA pflA SMU_1725 SMU_1725 cnhA cnhA ackA ackA prs prs tkt tkt pgi pgi SMU_352 SMU_352 gapC gapC pgk pgk SMU_362 SMU_362 glnR glnR glnA glnA gltA gltA gltB gltB pfl pfl pflC pflC pfl2 pfl2 SMU_494 SMU_494 gldA gldA pmgY pmgY citB citB citZ citZ idh idh gapN gapN tpiA tpiA SMU_913 SMU_913 fbaA fbaA
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a 3D structure is known or predicted
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SMU_1043cPutative phosphotransacetylase; Best Blastp Hit: sp|P39646|PTA_BACSU PROBABLE PHOSPHATE ACETYLTRANSFERASE (PHOSPHOTRANSACETYLASE) (VEGETATIVE PROTEIN 43) (VEG43) >gi|2126977|pir||S39743 phosphotransacetylase pta - Bacillus subtilis >gi|580883|emb|CAA51644.1| (X73124) ipa-88d [Bacillus subtilis] >gi|2636302|emb|CAB15793.1| (Z99123) phosphotransacetylase [Bacillus subtilis]. (331 aa)
krpSPutative phosphoribosylpyrophosphate synthetase, PRPP synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (326 aa)
ldhLactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (328 aa)
pykFPyruvate kinase; Best Blastp Hit: gb|AAF25804.1|AF172173_2 (AF172173) pyruvate kinase [Streptococcus thermophilus]. (500 aa)
pfk6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (337 aa)
deoBPutative phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (403 aa)
rpiAPutative ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (225 aa)
enoPutative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity). Binds plasminogen and human salivary mucin MG2 when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity that may help the dissemination through oral tissues and entrance into the blood stream; Belongs to the enolase family. (432 aa)
adhAPutative acetoin dehydrogenase (TPP-dependent), E1 component alpha subunit; Best Blastp Hit: dbj|BAB04495.1| (AP001509) acetoin dehydrogenase (TPP-dependent) alpha chain [Bacillus halodurans]. (331 aa)
adhBPutative acetoin dehydrogenase (TPP-dependent), E1 component beta subunit; Best Blastp Hit: dbj|BAB04496.1| (AP001509) acetoin dehydrogenase (TPP-dependent) beta chain [Bacillus halodurans]. (337 aa)
adhCBest Blastp Hit: dbj|BAB04497.1| (AP001509) dihydrolipoamide S-acetyltransferase [Bacillus halodurans]. (455 aa)
adhDBest Blastp Hit: pir||I40794 dihydrolipoamide dehydrogenase (EC 1.8.1.4) - Clostridium magnum >gi|472330|gb|AAA21748.1| (L31844) dihydrolipoamide dehydrogenase [Clostridium magnum]. (581 aa)
SMU_1309cBest Blastp Hit: pir||T37628 glycerol dehydrogenase - fission yeast (Schizosaccharomyces pombe) >gi|2398802|emb|CAB11766.1| (Z99091) glycerol dehydrogenase [Schizosaccharomyces pombe]. (363 aa)
lplABest Blastp Hit: pir||G69830 lipoate-protein ligase homolog yhfJ - Bacillus subtilis >gi|2226243|emb|CAA74531.1| (Y14083) hypothetical protein [Bacillus subtilis] >gi|2633361|emb|CAB12865.1| (Z99109) similar to lipoate-protein ligase [Bacillus subtilis]. (329 aa)
pdhCPutative dihydrolipoamide acetyltransferase, E2 component; Best Blastp Hit: sp|O31550|ACOC_BACSU DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF ACETOIN CLEAVING SYSTEM (ACETOIN DEHYDROGENASE E2 COMPONENT) >gi|7433670|pir||F69581 acetoin dehydrogenase E2 component (dihydrolipoamide acetyltra) acoC - Bacillus subtilis >gi|2633132|emb|CAB12637.1| (Z99108) acetoin dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [Bacillus subtilis] >gi|2780393|dbj|BAA24294.1| (D78509) YfjI [Bacillus subtilis]. (417 aa)
pdhBBest Blastp Hit: dbj|BAB05542.1| (AP001513) acetoin dehydrogenase E1 component (TPP-dependent beta subunit) [Bacillus halodurans]. (343 aa)
pdhAPutative pyruvate dehydrogenase, TPP-dependent E1 component alpha-subunit; Best Blastp Hit: pir||D69581 acetoin dehydrogenase E1 component (TPP-dependent alpha subuni) acoA - Bacillus subtilis >gi|2633130|emb|CAB12635.1| (Z99108) acetoin dehydrogenase E1 component (TPP-dependent alpha subunit) [Bacillus subtilis] >gi|2780395|dbj|BAA24296.1| (D78509) YfjK [Bacillus subtilis] >gi|2957146|gb|AAC05582.1| (AF006075) TPP-dependent acetoin dehydrogenase, E1 alpha-subunit [Bacillus subtilis]. (357 aa)
pdhDBest Blastp Hit: dbj|BAB04498.1| (AP001509) dihydrolipoamide dehydrogenase [Bacillus halodurans]. (445 aa)
SMU_1657cPutative nitrogen regulatory protein PII; Best Blastp Hit: emb|CAB94814.1| (AJ245582) hypothetical protein [Streptococcus thermophilus]. (113 aa)
nrgAPutative ammonium transporter, NrgA protein; Best Blastp Hit: gb|AAF73971.1| (U81166) NrgA-like protein [Lactococcus lactis subsp. cremoris]. (411 aa)
pflAPyruvate-formate lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (263 aa)
SMU_1725Putative acylphosphatase; Best Blastp Hit: pir||G72240 hypothetical protein TM1564 - Thermotoga maritima (strain MSB8) >gi|4982131|gb|AAD36630.1|AE001801_17 (AE001801) acylphosphatase, putative [Thermotoga maritima]. (92 aa)
cnhAPutative carbon-nitrogen hydrolase; Best Blastp Hit: pir||E69863 conserved hypothetical protein ykrU - Bacillus subtilis >gi|2633728|emb|CAB13230.1| (Z99111) similar to hypothetical proteins [Bacillus subtilis]. (258 aa)
ackAPutative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (399 aa)
prsPhosphoribosyl pyrophosphate synthetase (PRPP synthetase); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (322 aa)
tktTransketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (658 aa)
pgiGlucose-6-phosphate isomerase; Best Blastp Hit: gb|AAD33517.1|AF132127_2 (AF132127) glucose-6-phosphate isomerase [Streptococcus mutans]. (449 aa)
SMU_352Putative ribulose-phosphate-3-epimerase; Best Blastp Hit: dbj|BAB06221.1| (AP001515) unknown conserved protein [Bacillus halodurans]; Belongs to the ribulose-phosphate 3-epimerase family. (219 aa)
gapCExtracellular glyceraldehyde-3-phosphate dehydrogenase; Best Blastp Hit: sp|P50467|G3P_STRPY GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE (GAPDH) (PLASMINOGEN-BINDING PROTEIN) (PLASMIN RECEPTOR) >gi|285385|pir||A42963 glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) - Streptococcus sp >gi|153763|gb|AAA26953.1| (M95569) plasmin receptor [Streptococcus pyogenes]. (337 aa)
pgkPhosphoglycerate kinase; Best Blastp Hit: sp|Q9Z5C4|PGK_STAAU PHOSPHOGLYCERATE KINASE >gi|4490614|emb|CAB38646.1| (AJ133520) phosphoglycerate kinase [Staphylococcus aureus]; Belongs to the phosphoglycerate kinase family. (398 aa)
SMU_362Conserved hypothetical protein. (172 aa)
glnRBest Blastp Hit: sp|P19083|GLNR_BACCE REGULATORY PROTEIN GLNR >gi|80075|pir||JU0076 hypothetical 15K protein (glnA 5' region) - Bacillus cereus >gi|216272|dbj|BAA00402.1| (D00513) ORF129 [Bacillus cereus]. (123 aa)
glnABest Blastp Hit: gb|AAC44800.1| (U61271) glutamine synthetase type 1 [Streptococcus agalactiae]. (448 aa)
gltABest Blastp Hit: dbj|BAB05447.1| (AP001513) glutamate synthase (large subunit) [Bacillus halodurans]. (1505 aa)
gltBNADPH-dependent glutamate synthase (small subunit); Best Blastp Hit: dbj|BAA12742.1| (D85230) small subunit of NADH-dependent glutamate synthase [Plectonema boryanum]. (478 aa)
pflPyruvate formate-lyase; Best Blastp Hit: sp|Q59934|PFL_STRMU FORMATE ACETYLTRANSFERASE (PYRUVATE FORMATE-LYASE) >gi|1129082|dbj|BAA09085.1| (D50491) Pyruvate formate-lyase [Streptococcus mutans]. (775 aa)
pflCBest Blastp Hit: pir||A69431 probable pyruvate## formate-lyase activating enzyme (EC 1.97.1.4) pflC homolog - Archaeoglobus fulgidus >gi|2649121|gb|AAB89799.1| (AE001003) pyruvate formate-lyase 2 activating enzyme (pflC) [Archaeoglobus fulgidus]. (258 aa)
pfl2Best Blastp Hit: sp|P75793|PFLF_ECOLI PUTATIVE FORMATE ACETYLTRANSFERASE 3 (PYRUVATE FORMATE-LYASE 3) >gi|7427871|pir||G64819 probable formate C-acetyltransferase (EC 2.3.1.54) - Escherichia coli >gi|1787044|gb|AAC73910.1| (AE000184) putative formate acetyltransferase [Escherichia coli] >gi|4062397|dbj|BAA35511.1| (D90720) Formate acetyltransferase 2 (EC 2.3.1.54) (pyruvate formate-lyase 2). [Escherichia coli]. (818 aa)
SMU_494Putative transaldolase; Best Blastp Hit: emb|CAA05516.1| (AJ002527) OrfX [Clostridium beijerinckii]. (222 aa)
gldAGlycerol dehydrogenase; Best Blastp Hit: sp|P32816|GLDA_BACST GLYCEROL DEHYDROGENASE (GLDH) >gi|80206|pir||JQ1474 glycerol dehydrogenase (EC 1.1.1.6) - Bacillus stearothermophilus >gi|142978|gb|AAA22477.1| (M65289) glycerol dehydrogenase [Bacillus stearothermophilus]. (364 aa)
pmgYPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (230 aa)
citBAconitate hydratase; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein. (888 aa)
citZCitrate synthase; Best Blastp Hit: sp|Q59939|CISZ_STRMU CITRATE SYNTHASE >gi|1421813|gb|AAC44825.1| (U62799) citrate synthase [Streptococcus mutans]. (372 aa)
idhBest Blastp Hit: sp|Q59940|IDH_STRMU ISOCITRATE DEHYDROGENASE [NADP] (OXALOSUCCINATE DECARBOXYLASE) (IDH) (NADP+-SPECIFIC ICDH) (IDP) >gi|1421814|gb|AAC44826.1| (U62799) isocitrate dehydrogenase [Streptococcus mutans]. (393 aa)
gapNBest Blastp Hit: sp|Q59931|GAPN_STRMU NADP-DEPENDENT GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (NON-PHOSPHORYLATING GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE) (GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE [NADP+]) (TRIOSEPHOSPHATE DEHYDROGENASE) >gi|2117515|pir||A57151 glyceraldehyde-3-phosphate dehydrogenase (NADP+) (EC 1.2.1.9) - Streptococcus mutans >gi|5822059|pdb|1EUH|A Chain A, Apo Form Of A Nadp Dependent Aldehyde Dehydrogenase From Streptococcus Mutans >gi|5822060|pdb|1EUH|B Chain B, Apo Form Of A Nadp Dependent Aldehyde Dehydrogenase From Streptococcus Mutans >gi|5822061|pdb|1EUH|C [...] (475 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (252 aa)
SMU_913Best Blastp Hit: dbj|BAB05820.1| (AP001514) NADP-specific glutamate dehydrogenase [Bacillus halodurans]; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (449 aa)
fbaABest Blastp Hit: dbj|BAB16889.1| (AB050113) class-II aldolase [Streptococcus bovis]. (293 aa)
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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