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| | SMU_181 | Putative mevalonate kinase; Best Blastp Hit: gb|AAG02440.1|AF290093_1 (AF290093) mevalonate kinase [Enterococcus faecalis]. (332 aa) |
| | akh | Putative aspartokinase; Best Blastp Hit: sp|P94417|AK3_BACSU PROBABLE ASPARTOKINASE (ASPARTATE KINASE) >gi|7474867|pir||A69763 homoserine dehydrogenase homolog yclM - Bacillus subtilis >gi|1805449|dbj|BAA09011.1| (D50453) homologue of aspartokinase 2 alpha and beta subunits LysC of B. subtilis [Bacillus subtilis] >gi|2632680|emb|CAB12187.1| (Z99106) similar to homoserine dehydrogenase [Bacillus subtilis]; Belongs to the aspartokinase family. (452 aa) |
| | kthY | Putative thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (212 aa) |
| | pyrH | Putative uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (245 aa) |
| | dagK | Diacylglycerol kinase; Catalyzes the phosphorylation of undecaprenol, which is probably the primary physiological substrate. Is also able to phosphorylate diacylglycerol, albeit with very low efficiency. May play a role in adaptability to environmental stress conditions such as acid tolerance, elevated temperatures and high osmolarity. Belongs to the bacterial diacylglycerol kinase family. (137 aa) |
| | coaE | Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (198 aa) |
| | ptcB | Best Blastp Hit: pir||D82219 PTS system, cellobiose-specific IIB component VC1281 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9655767|gb|AAF94440.1| (AE004207) PTS system, cellobiose-specific IIB component [Vibrio cholerae]. (105 aa) |
| | SMU_1548c | Putative histidine kinase; Best Blastp Hit: emb|CAB54584.1| (AJ006400) histidine kinase [Streptococcus pneumoniae]. (336 aa) |
| | SMU_1542c | Best Blastp Hit: pir||F69795 conserved hypothetical protein yerQ - Bacillus subtilis >gi|2632986|emb|CAB12492.1| (Z99107) similar to hypothetical proteins [Bacillus subtilis]. (347 aa) |
| | covS | Putative histidine kinase CovS; Best Blastp Hit: emb|CAB65452.1| (AJ012051) VicK protein [Streptococcus pyogenes]. (450 aa) |
| | lacC | Tagatose-6-phosphate kinase; Best Blastp Hit: sp|P26421|LACC_STRMU TAGATOSE-6-PHOSPHATE KINASE (PHOSPHOTAGATOKINASE) >gi|322119|pir||E43258 tagatose-6-phosphate kinase - Streptococcus mutans >gi|153675|gb|AAA26906.1| (M80797) tagatose 6-P kinase [Streptococcus mutans]; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (310 aa) |
| | lacE | PTS system, lactose-specific enzyme IIBC EIIBC-LAC); The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II LacEF PTS system is involved in lactose transport. (568 aa) |
| | urk | Putative uridine kinase; Best Blastp Hit: sp|O32033|URK_BACSU URIDINE KINASE (URIDINE MONOPHOSPHOKINASE) >gi|7449167|pir||G69728 uridine kinase udk - Bacillus subtilis >gi|2635179|emb|CAB14675.1| (Z99117) uridine kinase [Bacillus subtilis]. (209 aa) |
| | SMU_1299c | Putative acetate kinase; Best Blastp Hit: gb|AAG09973.1|AF248038_2 (AF248038) acetate kinase [Streptococcus agalactiae]. (107 aa) |
| | grk | Putative glycerate kinase; Best Blastp Hit: sp|P57099|GRK_NEIMB GLYCERATE KINASE >gi|11279720|pir||F81102 conserved hypothetical protein NMB1268 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7226507|gb|AAF41645.1| (AE002475) conserved hypothetical protein [Neisseria meningitidis MC58]; Belongs to the glycerate kinase type-1 family. (370 aa) |
| | eno | Putative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity). Binds plasminogen and human salivary mucin MG2 when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity that may help the dissemination through oral tissues and entrance into the blood stream; Belongs to the enolase family. (432 aa) |
| | pfk | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (337 aa) |
| | pykF | Pyruvate kinase; Best Blastp Hit: gb|AAF25804.1|AF172173_2 (AF172173) pyruvate kinase [Streptococcus thermophilus]. (500 aa) |
| | mtlA1 | PTS system, mannitol-specific enzyme IIBC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport. (569 aa) |
| | mtlR | Putative transcriptional regulator, antiterminator; Not necessary for mannitol utilization. May be involved in regulation of the mannitol phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). (650 aa) |
| | mtlA2 | PTS system, mannitol-specific enzyme IIA; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport. (145 aa) |
| | SMU_1145c | Putative histidine kinase; Similar to RumK and ScnK; Best Blastp Hit: emb|CAB93670.1| (AJ276653) RumK protein [Ruminococcus gnavus]. (437 aa) |
| | SMU_1143c | Best Blastp Hit: gb|AAB64408.1| (U92073) macrolide-efflux protein [Streptococcus agalactiae]; Belongs to the ribF family. (306 aa) |
| | fruP | Putative fructose-1-phosphate kinase; Best Blastp Hit: dbj|BAB04546.1| (AP001510) fructose 1-phosphate kinase [Bacillus halodurans]; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (310 aa) |
| | ciaH | Putative histidine kinase sensor CiaH; Best Blastp Hit: sp|Q54955|CIAH_STRPN SENSOR PROTEIN CIAH >gi|1363426|pir||S49545 histidine kinase - Streptococcus pneumoniae >gi|495277|emb|CAA54466.1| (X77249) histidine kinase [Streptococcus pneumoniae] >gi|5830518|emb|CAB54565.1| (AJ005926) histidine kinase [Streptococcus pneumoniae]. (435 aa) |
| | coaA | Putative pantothenate kinase; Best Blastp Hit: dbj|BAB06594.1| (AP001516) pantothenate kinase [Bacillus halodurans]. (306 aa) |
| | ldh | Lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (328 aa) |
| | kitH | Putative thymidine kinase; Best Blastp Hit: sp|P47848|KITH_STRGC THYMIDINE KINASE >gi|703442|gb|AAB02289.1| (L40415) thymidine kinase [Streptococcus gordonii]. (194 aa) |
| | krpS | Putative phosphoribosylpyrophosphate synthetase, PRPP synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (326 aa) |
| | SMU_1046c | Putative GTP pyrophosphokinase; Best Blastp Hit: dbj|BAB06568.1| (AP001516) GTP pyrophosphokinase [Bacillus halodurans]. (221 aa) |
| | nadK | Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (277 aa) |
| | SMU_1037c | Putative histidine kinase; Best Blastp Hit: dbj|BAB04873.1| (AP001511) unknown conserved protein [Bacillus halodurans]. (292 aa) |
| | citG | Best Blastp Hit: pir||C82278 citG protein VC0801 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9655250|gb|AAF93965.1| (AE004165) citG protein [Vibrio cholerae]. (296 aa) |
| | SMU_1009 | Putative histidine kinase; Best Blastp Hit: emb|CAB54567.1| (AJ006391) histidine kinase [Streptococcus pneumoniae]. (317 aa) |
| | SMU_100 | Best Blastp Hit: gb|AAF24132.1|AF129168_5 (AF129168) EIIB sorbose-PTS homolog [Lactobacillus casei]. (163 aa) |
| | SMU_353 | Best Blastp Hit: pir||C69879 hypothetical protein yloS - Bacillus subtilis >gi|2337809|emb|CAA74253.1| (Y13937) YloS protein [Bacillus subtilis] >gi|2633952|emb|CAB13453.1| (Z99112) yloS [Bacillus subtilis]. (210 aa) |
| | pgk | Phosphoglycerate kinase; Best Blastp Hit: sp|Q9Z5C4|PGK_STAAU PHOSPHOGLYCERATE KINASE >gi|4490614|emb|CAB38646.1| (AJ133520) phosphoglycerate kinase [Staphylococcus aureus]; Belongs to the phosphoglycerate kinase family. (398 aa) |
| | proB | Putative gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (269 aa) |
| | SMU_45 | Hypothetical protein; Best Blastp Hit: emb|CAB73914.1| (AL139078) putative two-component sensor [Campylobacter jejuni]. (533 aa) |
| | ackA | Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (399 aa) |
| | kguA | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (210 aa) |
| | pknB | Putative serine/threonine protein kinase; Best Blastp Hit: emb|CAA10713.1| (AJ132604) hypothetical protein [Lactococcus lactis]. (616 aa) |
| | fbaA | Best Blastp Hit: dbj|BAB16889.1| (AB050113) class-II aldolase [Streptococcus bovis]. (293 aa) |
| | bglP | Putative PTS system, beta-glucoside-specific EII component; Best Blastp Hit: gb|AAF89975.1|AF206272_1 (AF206272) beta-glucoside-specific EII permease [Streptococcus mutans]. (644 aa) |
| | folK | Putative 2-amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphokinase; Best Blastp Hit: dbj|BAB03814.1| (AP001507) 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Bacillus halodurans]. (159 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (288 aa) |
| | SMU_954 | Putative pyridoxal kinase; Best Blastp Hit: dbj|BAB13727.1| (AB049010) pyridoxal kinase [Desulfovibrio vulgaris]; Belongs to the pyridoxine kinase family. (283 aa) |
| | SMU_938 | Putative phosphomevalonate kinase; Best Blastp Hit: gb|AAG02452.1|AF290097_3 (AF290097) phosphomevalonate kinase [Streptococcus pyogenes]. (332 aa) |
| | SMU_937 | Best Blastp Hit: gb|AAG02456.1|AF290099_2 (AF290099) mevalonate diphosphate decarboxylase [Streptococcus pneumoniae]. (310 aa) |
| | SMU_928 | Putative histidine kinase; Best Blastp Hit: gb|AAF79919.1| (AF039082) putative histidine protein kinase [Lactococcus lactis]. (412 aa) |
| | galK | Galactokinase, GalK; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (390 aa) |
| | pfkB | Putative fructose-1-phosphate kinase; Best Blastp Hit: sp|O31714|K1PF_BACSU 1-PHOSPHOFRUCTOKINASE (FRUCTOSE 1-PHOSPHATE KINASE) >gi|7434216|pir||A69627 fructose 1-phosphate kinase fruB - Bacillus subtilis >gi|2633810|emb|CAB13312.1| (Z99111) fructose-1-phosphate kinase [Bacillus subtilis] >gi|3282124|gb|AAC24914.1| (AF012285) fructose-1-phosphate kinase [Bacillus subtilis]; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (303 aa) |
| | thiD | Best Blastp Hit: sp|P39610|THID_BACSU PHOSPHOMETHYLPYRIMIDINE KINASE (HMP-PHOSPHATE KINASE) (HMP-P KINASE) >gi|629059|pir||S39707 phosphomethylpyrimidine kinase thiD - Bacillus subtilis >gi|413976|emb|CAA51608.1| (X73124) ipa-52r [Bacillus subtilis] >gi|2636337|emb|CAB15828.1| (Z99123) phosphomethylpyrimidine kinase [Bacillus subtilis]. (255 aa) |
| | aroK | Putative shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (158 aa) |
| | hprK | HPr(serine) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable [...] (311 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (252 aa) |
| | cmk | Putative cytidylate kinase; Best Blastp Hit: sp|P38493|KCY_BACSU CYTIDYLATE KINASE (CK) (CYTIDINE MONOPHOSPHATE KINASE) (CMP KINASE) >gi|7448348|pir||F69601 cytidylate kinase cmk - Bacillus subtilis >gi|533105|gb|AAA85149.1| (U11687) unknown [Bacillus subtilis] >gi|1146214|gb|AAC83961.1| (L47648) cytidine monophosphate kinase [Bacillus subtilis] >gi|2634707|emb|CAB14205.1| (Z99115) cytidylate kinase [Bacillus subtilis] >gi|2634724|emb|CAB14221.1| (Z99116) cytidylate kinase [Bacillus subtilis]. (227 aa) |
| | ptsI | Phosphoenolpyruvate:sugar phosphotransferase system enzyme I, PTS system EI component; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (577 aa) |
| | argB | Putative acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (245 aa) |
| | SMU_660 | Putative histidine kinase SpaK; Best Blastp Hit: sp|P33113|SPAK_BACSU SUBTILIN BIOSYNTHESIS SENSOR PROTEIN SPAK >gi|2702244|gb|AAB91593.1| (U09819) SpaK [Bacillus subtilis]. (460 aa) |
| | pmgY | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (230 aa) |
| | lytS | Putative histidine kinase LytS; Member of the two-component regulatory system LytR/LytS that probably regulates genes involved in cell wall metabolism. (580 aa) |
| | glk | Putative glucose kinase; Best Blastp Hit: pir||T44787 glucokinase (EC 2.7.1.2) [imported] - Bacillus megaterium >gi|2274867|emb|CAA03848.1| (AJ000005) glucose kinase [Bacillus megaterium]. (323 aa) |
| | SMU_486 | Putative histidine kinase; Best Blastp Hit: emb|CAB54570.1| (AJ006393) histidine kinase [Streptococcus pneumoniae]. (334 aa) |
| | ipk | Putative isopentenyl monophosphate kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. (282 aa) |
| | adk | Putative adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (212 aa) |
| | pttB | Best Blastp Hit: pir||B82263 PTS system, trehalose-specific IIBC component VC0910 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9655367|gb|AAF94072.1| (AE004175) PTS system, trehalose-specific IIBC component [Vibrio cholerae]. (655 aa) |
| | ptsG | Putative PTS system, glucose-specific IIABC component; Best Blastp Hit: gb|AAD00281.1| (U78600) putative ptsG## protein [Streptococcus mutans]. (729 aa) |
| | prs | Phosphoribosyl pyrophosphate synthetase (PRPP synthetase); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (322 aa) |
| | arcC | Putative carbamate kinase; Best Blastp Hit: pdb|1B7B|A Chain A, Carbamate Kinase From Enterococcus Faecium >gi|6980399|pdb|1B7B|B Chain B, Carbamate Kinase From Enterococcus Faecium >gi|6980400|pdb|1B7B|C Chain C, Carbamate Kinase From Enterococcus Faecium >gi|6980401|pdb|1B7B|D Chain D, Carbamate Kinase From Enterococcus Faecium >gi|2894540|emb|CAA11270.1| (AJ223331) carbamate kinase [Enterococcus faecium] >gi|2894542|emb|CAA11271.1| (AJ223332) carbamate kinase [Enterococcus faecalis]; Belongs to the carbamate kinase family. (316 aa) |
| | pgi | Glucose-6-phosphate isomerase; Best Blastp Hit: gb|AAD33517.1|AF132127_2 (AF132127) glucose-6-phosphate isomerase [Streptococcus mutans]. (449 aa) |
| | SMU_1965c | Putative histidine kinase; Best Blastp Hit: pir||T34676 probable sensor kinase - Streptomyces coelicolor >gi|4007712|emb|CAA22397.1| (AL034446) putative sensor kinase [Streptomyces coelicolor A3(2)]. (440 aa) |
| | SMU_1960c | Putative PTS system, mannose-specific IIB component; Best Blastp Hit: gb|AAB04152.1| (U28163) phosphoenolpyruvate:mannose phosphotransferase element IIB [Lactobacillus curvatus]. (164 aa) |
| | comD | Putative histidine kinase of the competence regulon, ComD; Best Blastp Hit: emb|CAC10175.1| (AJ278302) histidine kinase [Streptococcus pneumoniae]. (441 aa) |
| | ptnA | Putative PTS system, mannose-specific component IIAB; Best Blastp Hit: gb|AAD46485.1|AF130465_1 (AF130465) mannose-specific phosphotransferase system component IIAB [Streptococcus salivarius]. (330 aa) |
| | scrA | Putative PTS system, sucrose-specific IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in sucrose transport. (664 aa) |
| | scrK | Putative fructokinase; Best Blastp Hit: sp|Q07211|SCRK_STRMU FRUCTOKINASE >gi|287459|dbj|BAA02467.1| (D13175) fructokinase [Streptococcus mutans]. (293 aa) |
| | scnK | Putative histidine kinase, ScnK-like protein; Best Blastp Hit: pir||T09002 histidine kinase homolog scnK - Streptococcus pyogenes >gi|2502066|gb|AAB92598.1| (AF026542) ScnK [Streptococcus pyogenes]. (459 aa) |
