STRINGSTRING
SMU_299c SMU_299c SMU_367 SMU_367 SMU_448 SMU_448 pbp1a pbp1a SMU_510c SMU_510c ileS ileS SMU_587 SMU_587 spaP spaP sod sod SMU_633 SMU_633 SMU_63c SMU_63c SMU_662 SMU_662 SMU_689 SMU_689 SMU_695 SMU_695 thrC thrC Autolysin Autolysin SMU_707c SMU_707c SMU_739c SMU_739c SMU_75 SMU_75 SMU_751 SMU_751 SMU_76 SMU_76 gbpD gbpD SMU_775c SMU_775c fruA fruA SMU_789 SMU_789 fruB fruB SMU_807 SMU_807 SMU_820 SMU_820 rgpF rgpF SMU_831 SMU_831 SMU_836 SMU_836 SMU_855 SMU_855 agaL agaL gtfD gtfD SMU_94c SMU_94c wapA wapA SMU_609 SMU_609 gtfB gtfB gtfC gtfC SMU_106c SMU_106c srtA srtA pstS pstS SMU_118c SMU_118c SMU_1197 SMU_1197 SMU_12 SMU_12 eno eno SMU_1292c SMU_1292c SMU_1327c SMU_1327c SMU_1329c SMU_1329c SMU_139 SMU_139 SMU_1432c SMU_1432c SMU_1438c SMU_1438c SMU_1443c SMU_1443c pulA pulA SMU_1576c SMU_1576c amyA amyA vacB vacB murC murC SMU_1767c SMU_1767c manA manA scrB scrB SMU_1892c SMU_1892c SMU_1895c SMU_1895c pbp2a pbp2a SMU_196c SMU_196c SMU_1975c SMU_1975c sacB sacB dexA dexA gbpA gbpA SMU_2146c SMU_2146c SMU_2147c SMU_2147c SMU_226c SMU_226c aguA aguA
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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co-expression
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SMU_299cPutative bacteriocin peptide precursor; Best Blastp Hit: gb|AAG29818.1|AF298196_1 (AF298196) bovicin 255 peptide precursor [Streptococcus sp. LRC 0255]. (72 aa)
SMU_367Hypothetical protein; Best Blastp Hit: gb|AAB94651.1| (U96107) SceB precursor [Staphylococcus carnosus]. (211 aa)
SMU_448Hypothetical protein; Best Blastp Hit: pir||F69859 conserved hypothetical protein ykoJ - Bacillus subtilis >gi|2632048|emb|CAA05607.1| (AJ002571) YkoJ [Bacillus subtilis] >gi|2633682|emb|CAB13185.1| (Z99110) similar to hypothetical proteins from B. subtilis [Bacillus subtilis]. (126 aa)
pbp1aBest Blastp Hit: pir||S28031 penicillin-binding protein 1a - Streptococcus pneumoniae (strain 456) (fragment) >gi|47406|emb|CAA48068.1| (X67868) penicillin-binding protein 1a [Streptococcus pneumoniae] >gi|5410457|gb|AAD43066.1|AF139883_1 (AF139883) penicillin-binding protein 1a [Streptococcus pneumoniae]. (707 aa)
SMU_510cHypothetical protein; Best Blastp Hit: emb|CAA59264.1| (X84793) streptodornase [Streptococcus pyogenes]. (211 aa)
ileSisoleucine-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (930 aa)
SMU_587Conserved hypothetical protein; Best Blastp Hit: emb|CAA72096.1| (Y11213) hypothetical protein [Streptococcus thermophilus]. (285 aa)
spaPCell surface antigen SpaP; Surface protein antigen implicated in dental caries; Belongs to the SpaP/Ssp5/SpaA family. (1562 aa)
sodPutative manganese-type superoxide dismutase, Fe/Mn-SOD; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. (203 aa)
SMU_633Putative thioesterase; Best Blastp Hit: gb|AAF97985.1| (AY005822) peroxisomal long-chain acyl-coA thioesterase [Homo sapiens]. (409 aa)
SMU_63cBest Blastp Hit: pir||T33369 hypothetical protein H02F09.3 - Caenorhabditis elegans >gi|3319425|gb|AAC64622.1| (AF077538) unknown [Caenorhabditis elegans]. (613 aa)
SMU_662Conserved hypothetical protein; Best Blastp Hit: dbj|BAA11325.1| (D78257) ORF8 [Enterococcus faecalis]. (229 aa)
SMU_689Hypothetical protein; Best Blastp Hit: pir||C60328 hypothetical protein 2 (sr 5' region) - Streptococcus mutans (strain OMZ175, serotype f). (979 aa)
SMU_695Conserved hypothetical protein. (160 aa)
thrCPutative threonine synthase; Best Blastp Hit: sp|Q9ZMX5|THRC_HELPJ THREONINE SYNTHASE >gi|7437080|pir||A71975 threonine synthase - Helicobacter pylori (strain J99) >gi|4154598|gb|AAD05671.1| (AE001448) THREONINE SYNTHASE [Helicobacter pylori J99]. (494 aa)
AutolysinPutative autolysin; Best Blastp Hit: pir||T30211 autolysin E - Staphylococcus epidermidis >gi|2267242|gb|AAB63571.1| (U71377) autolysin AtlE [Staphylococcus epidermidis]. (327 aa)
SMU_707cPutative endolysin; Best Blastp Hit: emb|CAA72266.1| (Y11477) endolysin [Bacteriophage Bastille]. (282 aa)
SMU_739cHypothetical protein; Best Blastp Hit: gi|6319355 Ybl113cp [Saccharomyces cerevisiae] >gi|2131309|pir||S70305 hypothetical protein YBL113c - yeast (Saccharomyces cerevisiae). (518 aa)
SMU_75Best Blastp Hit: gb|AAD00280.1| (U78599) putative D,D-carboxypeptidase [Streptococcus mutans]. (249 aa)
SMU_751Conserved hypothetical protein; Best Blastp Hit: dbj|BAB04250.1| (AP001508) unknown conserved protein [Bacillus halodurans]. (708 aa)
SMU_76Best Blastp Hit: gb|AAD00279.1| (U78599) putative N-acetyl-muramidase [Streptococcus mutans]. (195 aa)
gbpDGlucan-binding protein D with lipase activity; Best Blastp Hit: gb|AAF89976.1|AF206272_2 (AF206272) BglB [Streptococcus mutans]. (726 aa)
SMU_775cConserved hypothetical protein; Best Blastp Hit: pir||C69810 anion-binding protein homolog yflE - Bacillus subtilis >gi|2443227|dbj|BAA22298.1| (D86417) YflE [Bacillus subtilis] >gi|2633095|emb|CAB12600.1| (Z99108) similar to anion-binding protein [Bacillus subtilis]. (717 aa)
fruAFructan hydrolase; This protein is a fructanase enzyme which degrades levans and inulins to fructose and also cleaves sucrose into glucose and fructose and can therefore function as an extracellular invertase; Belongs to the glycosyl hydrolase 32 family. (1423 aa)
SMU_789Conserved hypothetical protein; Best Blastp Hit: emb|CAC03528.1| (AJ276410) BlpY protein [Streptococcus pneumoniae]. (211 aa)
fruBFructan hydrolase; Best Blastp Hit: gb|AAD28639.1| (U78296) FruB [Streptococcus mutans]. (519 aa)
SMU_807Putative membrane protein; Best Blastp Hit: pir||T34651 probable transmembrane protein - Streptomyces coelicolor >gi|4007687|emb|CAA22372.1| (AL034446) putative transmembrane protein [Streptomyces coelicolor A3(2)]. (305 aa)
SMU_820Conserved hypothetical protein; Best Blastp Hit: pir||G41662 130K surface exclusion protein Sec10 precursor - Enterococcus faecalis plasmid pCF10 >gi|150554|gb|AAA65847.1| (M64978) surface exclusion protein [Plasmid pCF10]. (506 aa)
rgpFRgpFc protein; Best Blastp Hit: pir||T00091 rgpFc protein - Streptococcus mutans >gi|3399709|dbj|BAA32094.1| (AB010970) rgpFc [Streptococcus mutans]. (583 aa)
SMU_831Best Blastp Hit: pir||T00092 hypothetical protein 7 - Streptococcus mutans >gi|3399710|dbj|BAA32095.1| (AB010970) ORF7 [Streptococcus mutans]. (846 aa)
SMU_836Hypothetical protein; Best Blastp Hit: pir||C60328 hypothetical protein 2 (sr 5' region) - Streptococcus mutans (strain OMZ175, serotype f). (544 aa)
SMU_855Conserved hypothetical protein; Best Blastp Hit: sp|P76221|YDJZ_ECOLI HYPOTHETICAL 26.2 KD PROTEIN IN XTHA-GDHA INTERGENIC REGION >gi|7466221|pir||H64934 hypothetical protein b1752 - Escherichia coli (strain K-12) >gi|1788049|gb|AAC74822.1| (AE000270) orf, hypothetical protein [Escherichia coli]. (190 aa)
agaLAlpha-galactosidase; Best Blastp Hit: sp|P27756|AGAL_STRMU ALPHA-GALACTOSIDASE (MELIBIASE) >gi|322116|pir||A44819 alpha-galactosidase (EC 3.2.1.22) - Streptococcus mutans >gi|153736|gb|AAA26933.1| (M77351) a-galactosidase [Streptococcus mutans]; Belongs to the glycosyl hydrolase 36 family. (720 aa)
gtfDglucosyltransferase-S; Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris; Belongs to the glycosyl hydrolase 70 family. (1462 aa)
SMU_94cHypothetical protein; Best Blastp Hit: gb|AAF26677.1|AF165983_1 (AF165983) putative transposase [Streptococcus agalactiae]. (56 aa)
wapABest Blastp Hit: sp|P11000|WAPA_STRMU WALL-ASSOCIATED PROTEIN PRECURSOR >gi|98001|pir||S06992 wall-associated protein A precursor - Streptococcus mutans >gi|153858|gb|AAA88608.1| (M37842) wall-associated protein [Streptococcus mutans]. (453 aa)
SMU_609Best Blastp Hit: pir||A60328 40K cell wall protein precursor (sr 5' region) - Streptococcus mutans (strain OMZ175, serotype f). (611 aa)
gtfBglucosyltransferase-I; Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris; Belongs to the glycosyl hydrolase 70 family. (1476 aa)
gtfCglucosyltransferase-SI; Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris; Belongs to the glycosyl hydrolase 70 family. (1455 aa)
SMU_106cPutative transposase fragment; Best Blastp Hit: gb|AAF26677.1|AF165983_1 (AF165983) putative transposase [Streptococcus agalactiae]. (78 aa)
srtAPutative sortase; Best Blastp Hit: gb|AAA73122.1| (M77279) alpha-amylase [unidentified cloning vector]. (246 aa)
pstSPutative ABC transporter, phosphate-binding protein; Best Blastp Hit: sp|P46338|YQGG_BACSU PROBABLE ABC TRANSPORTER BINDING PROTEIN YQGG PRECURSOR >gi|7428856|pir||A69956 phosphate ABC transporter (binding protein) homolog yqgG - Bacillus subtilis >gi|903303|dbj|BAA09581.1| (D58414) ORF108 [Bacillus subtilis] >gi|1303854|dbj|BAA12510.1| (D84432) YqgG [Bacillus subtilis] >gi|2634932|emb|CAB14429.1| (Z99116) alternate gene name: yzmB similar to phosphate ABC transporter (binding protein) [Bacillus subtilis]. (287 aa)
SMU_118cPutative esterase; Serine hydrolase involved in the detoxification of formaldehyde. (280 aa)
SMU_1197Conserved hypothetical protein; Best Blastp Hit: sp|P76219|YDJX_ECOLI HYPOTHETICAL 26.1 KD PROTEIN IN XTHA-GDHA INTERGENIC REGION >gi|1742859|dbj|BAA15541.1| (D90818) ORF_ID:o327#7; similar to [SwissProt Accession Number P54449] [Escherichia coli] >gi|1742864|dbj|BAA15545.1| (D90819) ORF_ID:o327#7; similar to [SwissProt Accession Number P54449] [Escherichia coli]. (204 aa)
SMU_12Conserved hypothetical protein; Best Blastp Hit: pir||I39830 penicillin binding protein 5 - Bacillus subtilis (fragment) >gi|142817|gb|AAA22375.1| (M13766) penicillin binding protein 5 [Bacillus subtilis]. (404 aa)
enoPutative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity). Binds plasminogen and human salivary mucin MG2 when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity that may help the dissemination through oral tissues and entrance into the blood stream; Belongs to the enolase family. (432 aa)
SMU_1292cConserved hypothetical protein; Best Blastp Hit: sp|P54449|YQED_BACSU HYPOTHETICAL 22.9 KD PROTEIN IN NUCB-AROD INTERGENIC REGION >gi|7474688|pir||H69950 conserved hypothetical protein yqeD - Bacillus subtilis >gi|1303784|dbj|BAA12440.1| (D84432) YqeD [Bacillus subtilis] >gi|2635017|emb|CAB14513.1| (Z99117) similar to hypothetical proteins [Bacillus subtilis]. (225 aa)
SMU_1327cBest Blastp Hit: pir||E69820 conserved hypothetical protein yhbA - Bacillus subtilis >gi|1903044|emb|CAB07527.1| (Z93102) hypothetical 48.5 kd protein [Bacillus subtilis] >gi|2633214|emb|CAB12719.1| (Z99108) alternate gene name: ygaP similar to hypothetical proteins [Bacillus subtilis]. (373 aa)
SMU_1329cPutative transposase; Best Blastp Hit: gb|AAF26677.1|AF165983_1 (AF165983) putative transposase [Streptococcus agalactiae]. (157 aa)
SMU_139Best Blastp Hit: pir||E70047 conserved hypothetical protein yvrK - Bacillus subtilis >gi|2635821|emb|CAB15314.1| (Z99120) similar to hypothetical proteins [Bacillus subtilis] >gi|2635837|emb|CAB15329.1| (Z99121) similar to hypothetical proteins [Bacillus subtilis] >gi|2832803|emb|CAA11727.1| (AJ223978) YvrK protein [Bacillus subtilis]. (394 aa)
SMU_1432cPutative endoglucanase precursor; Best Blastp Hit: sp|P19254|GUB_BACCI BETA-GLUCANASE PRECURSOR (ENDO-BETA-1,3-1,4 GLUCANASE) >gi|98112|pir||S10485 licheninase (EC 3.2.1.73) - Bacillus circulans >gi|39416|emb|CAA37062.1| (X52880) lichenase (AA 1-409) [Bacillus circulans]; Belongs to the glycosyl hydrolase 8 (cellulase D) family. (295 aa)
SMU_1438cPutative Zn-dependent protease; Best Blastp Hit: emb|CAA71521.1| (Y10497) protease A [Myxococcus xanthus]. (232 aa)
SMU_1443cPutative tributyrin esterase; Best Blastp Hit: gb|AAF62860.1| (AF157601) tributyrin esterase [Lactococcus lactis subsp. cremoris]. (263 aa)
pulAPutative pullulanase; Best Blastp Hit: prf||1808262A thermostable pullulanase [Bacillus stearothermophilus]; Belongs to the glycosyl hydrolase 13 family. (743 aa)
SMU_1576cHypothetical protein; Best Blastp Hit: pir||G71620 hypothetical protein PFB0195c - malaria parasite (Plasmodium falciparum) >gi|3845121|gb|AAC71828.1| (AE001380) hypothetical protein [Plasmodium falciparum]. (682 aa)
amyAIntracellular alpha-amylase; Best Blastp Hit: gb|AAC35010.1| (AF055987) intracellular a-amylase [Streptococcus mutans]. (486 aa)
vacBPutative exoribonuclease R (RNAase R); 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (778 aa)
murCPutative UDP-N-acetyl muramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (452 aa)
SMU_1767cHypothetical protein; Best Blastp Hit: gb|AAF13791.1|AF129502_2 (AF129502) acetohydroxy acid synthase large subunit [Buchnera aphidicola]. (63 aa)
manABest Blastp Hit: sp|Q59935|MANA_STRMU MANNOSE-6-PHOSPHATE ISOMERASE (PHOSPHOMANNOSE ISOMERASE) (PMI) (PHOSPHOHEXOMUTASE) >gi|451216|dbj|BAA04021.1| (D16594) Mannosephosphate Isomerase [Streptococcus mutans]. (316 aa)
scrBBest Blastp Hit: sp|P13522|SCRB_STRMU SUCROSE-6-PHOSPHATE## HYDROLASE (SUCRASE) (INVERTASE) >gi|97999|pir||A43501 sucrose-6-phosphate hydrolase - Streptococcus mutans >gi|47259|emb|CAA35872.1| (X51507) sucrose-6-phosphate hydrolase [Streptococcus mutans] >gi|153804|gb|AAA26972.1| (M36849) sucrose-6-phosphate hydrolase [Streptococcus mutans]. (479 aa)
SMU_1892cHypothetical protein. (61 aa)
SMU_1895cHypothetical protein; Best Blastp Hit: emb|CAC03521.1| (AJ276410) BlpJ protein [Streptococcus pneumoniae]. (53 aa)
pbp2aBest Blastp Hit: gb|AAF04735.1|AF101780_1 (AF101780) penicillin-binding protein 2a [Streptococcus pneumoniae]. (730 aa)
SMU_196cPutative transfer protein; Best Blastp Hit: emb|CAB70620.1| (AJ243106) transfer protein [Streptococcus thermophilus]. (365 aa)
SMU_1975cConserved hypothetical protein; Best Blastp Hit: dbj|BAA11325.1| (D78257) ORF8 [Enterococcus faecalis]. (220 aa)
sacBLevansucrase precursor; Best Blastp Hit: sp|P11701|SACB_STRMU LEVANSUCRASE## PRECURSOR (BETA-D-FRUCTOFURANOSYL TRANSFERASE) (SUCROSE 6-FRUCTOSYL TRANSFERASE) >gi|79999|pir||B28551 levansucrase (EC 2.4.1.10) precursor - Streptococcus mutans (strain GS-5) >gi|153636|gb|AAA88584.1| (M18954) fructosyltransferase [Streptococcus mutans]; Belongs to the glycosyl hydrolase 68 family. (795 aa)
dexADextranase precursor; May play a role in sucrose-independent adherence to the pellicle-coated tooth surface; Belongs to the glycosyl hydrolase 66 family. (850 aa)
gbpABest Blastp Hit: pir||A37184 glucan-binding protein - Streptococcus mutans >gi|153638|gb|AAA26894.1| (M30945) glucan-binding protein (gbp) [Streptococcus mutans]. (565 aa)
SMU_2146cHypothetical protein; Best Blastp Hit: gb|AAF66691.1|AF144681_1 (AF144681) immunodominant antigen A [Staphylococcus aureus]. (201 aa)
SMU_2147cConserved hypothetical protein; Best Blastp Hit: emb|CAA69725.1| (Y08498) aggregation promoting protein [Lactobacillus gasseri]. (288 aa)
SMU_226cPutative transposase; Best Blastp Hit: gb|AAF26677.1|AF165983_1 (AF165983) putative transposase [Streptococcus agalactiae]. (182 aa)
aguAConserved hypothetical protein; Best Blastp Hit: gb|AAG03681.1|AE004467_3 (AE004467) conserved hypothetical protein [Pseudomonas aeruginosa]. (369 aa)
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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