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msmF msmF msmK msmK bglP bglP SMU_1118c SMU_1118c fruC fruC mtlA2 mtlA2 SMU_105 SMU_105 mtlA1 mtlA1 lacE lacE lacF lacF ptcC ptcC scrA scrA pttB pttB ptsG ptsG ptsH ptsH ptsI ptsI fruI fruI msmE msmE msmG msmG
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
msmFMultiple sugar-binding ABC transporter, permease protein MsmF; Involved in a binding protein-dependent transport system responsible for the uptake of melibiose, raffinose and isomaltotriose; Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily. (290 aa)
msmKMultiple sugar-binding ABC transporter, ATP-binding protein, MsmK; Involved in a binding protein-dependent transport system responsible for the uptake of melibiose, raffinose and isomaltotriose. Probably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. (377 aa)
bglPPutative PTS system, beta-glucoside-specific EII component; Best Blastp Hit: gb|AAF89975.1|AF206272_1 (AF206272) beta-glucoside-specific EII permease [Streptococcus mutans]. (644 aa)
SMU_1118cPutative ABC sugar transporter, permease protein; Best Blastp Hit: pir||F70009 conserved hypothetical protein yufQ - Bacillus subtilis >gi|1934814|emb|CAB07939.1| (Z93937) unknown## [Bacillus subtilis] >gi|2635653|emb|CAB15146.1| (Z99120) similar to hypothetical proteins [Bacillus subtilis]; Belongs to the binding-protein-dependent transport system permease family. (318 aa)
fruCBest Blastp Hit: dbj|BAB04547.1| (AP001510) PTS system, fructose-specific enzyme II, BC component [Bacillus halodurans]. (466 aa)
mtlA2PTS system, mannitol-specific enzyme IIA; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport. (145 aa)
SMU_105Putative transcriptional regulator; Best Blastp Hit: sp|Q54430|SCRR_STRMU SUCROSE OPERON REPRESSOR (SCR OPERON REGULATORY PROTEIN) >gi|1184967|gb|AAC31628.1| (U46902) ScrR [Streptococcus mutans]. (332 aa)
mtlA1PTS system, mannitol-specific enzyme IIBC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport. (569 aa)
lacEPTS system, lactose-specific enzyme IIBC EIIBC-LAC); The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II LacEF PTS system is involved in lactose transport. (568 aa)
lacFPTS system, lactose-specific enzyme IIA EIIA-LAC); The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II LacEF PTS system is involved in lactose transport. (104 aa)
ptcCPutative PTS system, cellobiose-specific IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (452 aa)
scrAPutative PTS system, sucrose-specific IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in sucrose transport. (664 aa)
pttBBest Blastp Hit: pir||B82263 PTS system, trehalose-specific IIBC component VC0910 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9655367|gb|AAF94072.1| (AE004175) PTS system, trehalose-specific IIBC component [Vibrio cholerae]. (655 aa)
ptsGPutative PTS system, glucose-specific IIABC component; Best Blastp Hit: gb|AAD00281.1| (U78600) putative ptsG## protein [Streptococcus mutans]. (729 aa)
ptsHPhosphoenolpyruvate:sugar phosphotransferase system HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain. (87 aa)
ptsIPhosphoenolpyruvate:sugar phosphotransferase system enzyme I, PTS system EI component; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (577 aa)
fruIBest Blastp Hit: dbj|BAB04547.1| (AP001510) PTS system, fructose-specific enzyme II, BC component [Bacillus halodurans]. (655 aa)
msmEMultiple sugar-binding ABC transporter, sugar-binding protein precursor MsmE; Involved in a binding protein-dependent transport system responsible for the uptake of melibiose, raffinose and isomaltotriose. (420 aa)
msmGMultiple sugar-binding ABC transporter, permease protein MsmG; Involved in a binding protein-dependent transport system responsible for the uptake of melibiose, raffinose and isomaltotriose; Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily. (277 aa)
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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