node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SMU_1043c | ackA | SMU_1043c | SMU_1978 | Putative phosphotransacetylase; Best Blastp Hit: sp|P39646|PTA_BACSU PROBABLE PHOSPHATE ACETYLTRANSFERASE (PHOSPHOTRANSACETYLASE) (VEGETATIVE PROTEIN 43) (VEG43) >gi|2126977|pir||S39743 phosphotransacetylase pta - Bacillus subtilis >gi|580883|emb|CAA51644.1| (X73124) ipa-88d [Bacillus subtilis] >gi|2636302|emb|CAB15793.1| (Z99123) phosphotransacetylase [Bacillus subtilis]. | Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.999 |
SMU_1296 | tpx | SMU_1296 | SMU_924 | Putative glutathione S-transferase; Best Blastp Hit: pir||C65085 hypothetical protein b2989 - Escherichia coli (strain K-12) >gi|882518|gb|AAA69156.1| (U28377) ORF_o304; GTG start [Escherichia coli] >gi|1789363|gb|AAC76025.1| (AE000382) orf, hypothetical protein [Escherichia coli]; Belongs to the GST superfamily. | Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. | 0.640 |
SMU_833 | luxS | SMU_833 | SMU_474 | Putative glycosyltransferase; Best Blastp Hit: sp|Q45539|CSBB_BACSU CSBB PROTEIN >gi|2126920|pir||JC5173 stress response protein csbB - Bacillus subtilis >gi|1387979|gb|AAB38429.1| (L77099) 44% identity over 302 residues with hypothetical protein from Synechocystis sp, accession D64006_CD; expression induced by environmental stress; some similarity to glycosyl transferases; two potential membrane-spanning helices [Bacillus subtil> >gi|2633183|emb|CAB12688.1| (Z99108) stress response protein [Bacillus subtilis] >gi|2804544|dbj|BAA24480.1| (D85082) YfhN [Bacillus subtilis]. | Putative autoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.623 |
SMU_833 | rgpE | SMU_833 | SMU_829 | Putative glycosyltransferase; Best Blastp Hit: sp|Q45539|CSBB_BACSU CSBB PROTEIN >gi|2126920|pir||JC5173 stress response protein csbB - Bacillus subtilis >gi|1387979|gb|AAB38429.1| (L77099) 44% identity over 302 residues with hypothetical protein from Synechocystis sp, accession D64006_CD; expression induced by environmental stress; some similarity to glycosyl transferases; two potential membrane-spanning helices [Bacillus subtil> >gi|2633183|emb|CAB12688.1| (Z99108) stress response protein [Bacillus subtilis] >gi|2804544|dbj|BAA24480.1| (D85082) YfhN [Bacillus subtilis]. | Best Blastp Hit: pir||T00090 glycosyltransferase rgpEc - Streptococcus mutans >gi|3399708|dbj|BAA32093.1| (AB010970) glycosyltransferase [Streptococcus mutans]. | 0.645 |
ackA | SMU_1043c | SMU_1978 | SMU_1043c | Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Putative phosphotransacetylase; Best Blastp Hit: sp|P39646|PTA_BACSU PROBABLE PHOSPHATE ACETYLTRANSFERASE (PHOSPHOTRANSACETYLASE) (VEGETATIVE PROTEIN 43) (VEG43) >gi|2126977|pir||S39743 phosphotransacetylase pta - Bacillus subtilis >gi|580883|emb|CAA51644.1| (X73124) ipa-88d [Bacillus subtilis] >gi|2636302|emb|CAB15793.1| (Z99123) phosphotransacetylase [Bacillus subtilis]. | 0.999 |
ackA | ccpA | SMU_1978 | SMU_1591 | Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Catabolite control protein A, CcpA; Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions. | 0.712 |
ackA | comYB | SMU_1978 | SMU_1985 | Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Best Blastp Hit: gb|AAC45311.1| (U81957) putative ABC transporter subunit ComYB [Streptococcus gordonii]. | 0.542 |
brpA | luxS | SMU_410 | SMU_474 | Putative transcriptional regulator; Involved in biofilm formation, cell division, autolysis and the regulation of acid and oxidative stress tolerance. May be associated with systemic virulence in blood. Belongs to the LytR/CpsA/Psr (LCP) family. | Putative autoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.802 |
brpA | ropA | SMU_410 | SMU_91 | Putative transcriptional regulator; Involved in biofilm formation, cell division, autolysis and the regulation of acid and oxidative stress tolerance. May be associated with systemic virulence in blood. Belongs to the LytR/CpsA/Psr (LCP) family. | Peptidyl-prolyl isomerase RopA (trigger factor); Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.431 |
ccpA | ackA | SMU_1591 | SMU_1978 | Catabolite control protein A, CcpA; Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions. | Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.712 |
comYB | ackA | SMU_1985 | SMU_1978 | Best Blastp Hit: gb|AAC45311.1| (U81957) putative ABC transporter subunit ComYB [Streptococcus gordonii]. | Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.542 |
luxS | SMU_833 | SMU_474 | SMU_833 | Putative autoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | Putative glycosyltransferase; Best Blastp Hit: sp|Q45539|CSBB_BACSU CSBB PROTEIN >gi|2126920|pir||JC5173 stress response protein csbB - Bacillus subtilis >gi|1387979|gb|AAB38429.1| (L77099) 44% identity over 302 residues with hypothetical protein from Synechocystis sp, accession D64006_CD; expression induced by environmental stress; some similarity to glycosyl transferases; two potential membrane-spanning helices [Bacillus subtil> >gi|2633183|emb|CAB12688.1| (Z99108) stress response protein [Bacillus subtilis] >gi|2804544|dbj|BAA24480.1| (D85082) YfhN [Bacillus subtilis]. | 0.623 |
luxS | brpA | SMU_474 | SMU_410 | Putative autoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | Putative transcriptional regulator; Involved in biofilm formation, cell division, autolysis and the regulation of acid and oxidative stress tolerance. May be associated with systemic virulence in blood. Belongs to the LytR/CpsA/Psr (LCP) family. | 0.802 |
luxS | rgpE | SMU_474 | SMU_829 | Putative autoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | Best Blastp Hit: pir||T00090 glycosyltransferase rgpEc - Streptococcus mutans >gi|3399708|dbj|BAA32093.1| (AB010970) glycosyltransferase [Streptococcus mutans]. | 0.600 |
luxS | ropA | SMU_474 | SMU_91 | Putative autoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | Peptidyl-prolyl isomerase RopA (trigger factor); Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.719 |
rgpE | SMU_833 | SMU_829 | SMU_833 | Best Blastp Hit: pir||T00090 glycosyltransferase rgpEc - Streptococcus mutans >gi|3399708|dbj|BAA32093.1| (AB010970) glycosyltransferase [Streptococcus mutans]. | Putative glycosyltransferase; Best Blastp Hit: sp|Q45539|CSBB_BACSU CSBB PROTEIN >gi|2126920|pir||JC5173 stress response protein csbB - Bacillus subtilis >gi|1387979|gb|AAB38429.1| (L77099) 44% identity over 302 residues with hypothetical protein from Synechocystis sp, accession D64006_CD; expression induced by environmental stress; some similarity to glycosyl transferases; two potential membrane-spanning helices [Bacillus subtil> >gi|2633183|emb|CAB12688.1| (Z99108) stress response protein [Bacillus subtilis] >gi|2804544|dbj|BAA24480.1| (D85082) YfhN [Bacillus subtilis]. | 0.645 |
rgpE | luxS | SMU_829 | SMU_474 | Best Blastp Hit: pir||T00090 glycosyltransferase rgpEc - Streptococcus mutans >gi|3399708|dbj|BAA32093.1| (AB010970) glycosyltransferase [Streptococcus mutans]. | Putative autoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.600 |
ropA | brpA | SMU_91 | SMU_410 | Peptidyl-prolyl isomerase RopA (trigger factor); Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | Putative transcriptional regulator; Involved in biofilm formation, cell division, autolysis and the regulation of acid and oxidative stress tolerance. May be associated with systemic virulence in blood. Belongs to the LytR/CpsA/Psr (LCP) family. | 0.431 |
ropA | luxS | SMU_91 | SMU_474 | Peptidyl-prolyl isomerase RopA (trigger factor); Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | Putative autoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.719 |
tpx | SMU_1296 | SMU_924 | SMU_1296 | Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. | Putative glutathione S-transferase; Best Blastp Hit: pir||C65085 hypothetical protein b2989 - Escherichia coli (strain K-12) >gi|882518|gb|AAA69156.1| (U28377) ORF_o304; GTG start [Escherichia coli] >gi|1789363|gb|AAC76025.1| (AE000382) orf, hypothetical protein [Escherichia coli]; Belongs to the GST superfamily. | 0.640 |