STRINGSTRING
ackA ackA SMU_1296 SMU_1296 recJ recJ ccpA ccpA SMU_1043c SMU_1043c comYB comYB brpA brpA luxS luxS lytS lytS SMU_707c SMU_707c rgpE rgpE SMU_833 SMU_833 ropA ropA tpx tpx
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ackAPutative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (399 aa)
SMU_1296Putative glutathione S-transferase; Best Blastp Hit: pir||C65085 hypothetical protein b2989 - Escherichia coli (strain K-12) >gi|882518|gb|AAA69156.1| (U28377) ORF_o304; GTG start [Escherichia coli] >gi|1789363|gb|AAC76025.1| (AE000382) orf, hypothetical protein [Escherichia coli]; Belongs to the GST superfamily. (263 aa)
recJBest Blastp Hit: pir||H69980 single-strand DNA-specific exonuclease homolog yrvE - Bacillus subtilis >gi|2635226|emb|CAB14721.1| (Z99118) similar to single-strand DNA-specific exonuclease [Bacillus subtilis]. (734 aa)
ccpACatabolite control protein A, CcpA; Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions. (333 aa)
SMU_1043cPutative phosphotransacetylase; Best Blastp Hit: sp|P39646|PTA_BACSU PROBABLE PHOSPHATE ACETYLTRANSFERASE (PHOSPHOTRANSACETYLASE) (VEGETATIVE PROTEIN 43) (VEG43) >gi|2126977|pir||S39743 phosphotransacetylase pta - Bacillus subtilis >gi|580883|emb|CAA51644.1| (X73124) ipa-88d [Bacillus subtilis] >gi|2636302|emb|CAB15793.1| (Z99123) phosphotransacetylase [Bacillus subtilis]. (331 aa)
comYBBest Blastp Hit: gb|AAC45311.1| (U81957) putative ABC transporter subunit ComYB [Streptococcus gordonii]. (282 aa)
brpAPutative transcriptional regulator; Involved in biofilm formation, cell division, autolysis and the regulation of acid and oxidative stress tolerance. May be associated with systemic virulence in blood. Belongs to the LytR/CpsA/Psr (LCP) family. (406 aa)
luxSPutative autoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (160 aa)
lytSPutative histidine kinase LytS; Member of the two-component regulatory system LytR/LytS that probably regulates genes involved in cell wall metabolism. (580 aa)
SMU_707cPutative endolysin; Best Blastp Hit: emb|CAA72266.1| (Y11477) endolysin [Bacteriophage Bastille]. (282 aa)
rgpEBest Blastp Hit: pir||T00090 glycosyltransferase rgpEc - Streptococcus mutans >gi|3399708|dbj|BAA32093.1| (AB010970) glycosyltransferase [Streptococcus mutans]. (465 aa)
SMU_833Putative glycosyltransferase; Best Blastp Hit: sp|Q45539|CSBB_BACSU CSBB PROTEIN >gi|2126920|pir||JC5173 stress response protein csbB - Bacillus subtilis >gi|1387979|gb|AAB38429.1| (L77099) 44% identity over 302 residues with hypothetical protein from Synechocystis sp, accession D64006_CD; expression induced by environmental stress; some similarity to glycosyl transferases; two potential membrane-spanning helices [Bacillus subtil> >gi|2633183|emb|CAB12688.1| (Z99108) stress response protein [Bacillus subtilis] >gi|2804544|dbj|BAA24480.1| (D85082) YfhN [Bacillus subtilis]. (308 aa)
ropAPeptidyl-prolyl isomerase RopA (trigger factor); Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (427 aa)
tpxThiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (161 aa)
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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