STRINGSTRING
gtfD gtfD gtfB gtfB gtfC gtfC SMU_102 SMU_102 SMU_104 SMU_104 SMU_109 SMU_109 gbpC gbpC ftsK ftsK comC comC comD comD comE comE gcrR gcrR mreC mreC sacB sacB mreD mreD gbpA gbpA gbpB gbpB plsX plsX SMU_486 SMU_486 SMU_52 SMU_52 gbpD gbpD hrcA hrcA rgpE rgpE SMU_833 SMU_833 SMU_86 SMU_86
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gtfDglucosyltransferase-S; Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris; Belongs to the glycosyl hydrolase 70 family. (1462 aa)
gtfBglucosyltransferase-I; Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris; Belongs to the glycosyl hydrolase 70 family. (1476 aa)
gtfCglucosyltransferase-SI; Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris; Belongs to the glycosyl hydrolase 70 family. (1455 aa)
SMU_102Putative PTS system, IID component; Best Blastp Hit: gb|AAC44681.1| (U65015) PTS permease for mannose subunit IIBMan [Vibrio furnissii]. (273 aa)
SMU_104Putative alpha-glucosidase; Best Blastp Hit: emb|CAB99206.1| (AJ251975) alpha-xylosidase [Sulfolobus solfataricus]; Belongs to the glycosyl hydrolase 31 family. (731 aa)
SMU_109Conserved hypothetical protein; Best Blastp Hit: gb|AAG32545.1| (U12643) Dsg [Streptococcus gordonii]. (366 aa)
gbpCGlucan-binding protein C, GbpC; Best Blastp Hit: dbj|BAA12713.1| (D85031) glucan-binding protein C [Streptococcus mutans]. (583 aa)
ftsKPutative cell division protein; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the difSL recombination site, which is located within the replication terminus region. Required for activation of the XerS recombinase, allowing activation of chromosome unlinking by recombination (By similarity). Belongs to the FtsK/SpoIIIE/SftA family. (758 aa)
comCCompetence stimulating peptide, precursor. (46 aa)
comDPutative histidine kinase of the competence regulon, ComD; Best Blastp Hit: emb|CAC10175.1| (AJ278302) histidine kinase [Streptococcus pneumoniae]. (441 aa)
comEPutative response regulator of the competence regulon, ComE; Best Blastp Hit: gb|AAB41200.1| (U75483) sakacin A production response regulator [Streptococcus mutans]. (250 aa)
gcrRResponse regulator GcrR for glucan-binding protein C; Best Blastp Hit: dbj|BAA85986.1| (AB024522) gcrR [Streptococcus mutans]. (230 aa)
mreCPutative cell shape-determining protein MreC; Involved in formation and maintenance of cell shape. (269 aa)
sacBLevansucrase precursor; Best Blastp Hit: sp|P11701|SACB_STRMU LEVANSUCRASE## PRECURSOR (BETA-D-FRUCTOFURANOSYL TRANSFERASE) (SUCROSE 6-FRUCTOSYL TRANSFERASE) >gi|79999|pir||B28551 levansucrase (EC 2.4.1.10) precursor - Streptococcus mutans (strain GS-5) >gi|153636|gb|AAA88584.1| (M18954) fructosyltransferase [Streptococcus mutans]; Belongs to the glycosyl hydrolase 68 family. (795 aa)
mreDPutative cell shape-determining protein MreD; Best Blastp Hit: gb|AAF86216.1|AF242196_2 (AF242196) MreD [Enterococcus faecium] >gi|9367035|gb|AAF87091.1|AF167575_1 (AF167575) MreD [Enterococcus faecium]. (168 aa)
gbpABest Blastp Hit: pir||A37184 glucan-binding protein - Streptococcus mutans >gi|153638|gb|AAA26894.1| (M30945) glucan-binding protein (gbp) [Streptococcus mutans]. (565 aa)
gbpBBest Blastp Hit: gb|AAD00288.1| (U78607) putative secreted protein [Streptococcus mutans]. (431 aa)
plsXPutative fatty acid/phospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (332 aa)
SMU_486Putative histidine kinase; Best Blastp Hit: emb|CAB54570.1| (AJ006393) histidine kinase [Streptococcus pneumoniae]. (334 aa)
SMU_52Best Blastp Hit: pir||T18433 hypothetical protein C0370w - Plasmodium falciparum >gi|3649761|emb|CAB11110.1| (Z98547) predicted using hexExon; MAL3P3.9 (PFC0370w), Hypothetical protein, len: 431 aa [Plasmodium falciparum]. (221 aa)
gbpDGlucan-binding protein D with lipase activity; Best Blastp Hit: gb|AAF89976.1|AF206272_2 (AF206272) BglB [Streptococcus mutans]. (726 aa)
hrcATranscriptional regulator; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. (344 aa)
rgpEBest Blastp Hit: pir||T00090 glycosyltransferase rgpEc - Streptococcus mutans >gi|3399708|dbj|BAA32093.1| (AB010970) glycosyltransferase [Streptococcus mutans]. (465 aa)
SMU_833Putative glycosyltransferase; Best Blastp Hit: sp|Q45539|CSBB_BACSU CSBB PROTEIN >gi|2126920|pir||JC5173 stress response protein csbB - Bacillus subtilis >gi|1387979|gb|AAB38429.1| (L77099) 44% identity over 302 residues with hypothetical protein from Synechocystis sp, accession D64006_CD; expression induced by environmental stress; some similarity to glycosyl transferases; two potential membrane-spanning helices [Bacillus subtil> >gi|2633183|emb|CAB12688.1| (Z99108) stress response protein [Bacillus subtilis] >gi|2804544|dbj|BAA24480.1| (D85082) YfhN [Bacillus subtilis]. (308 aa)
SMU_86Best Blastp Hit: sp|P20298|YORX_PYRWO HYPOTHETICAL PROTEIN IN GAPDH 3'REGION (ORF X) >gi|81090|pir||S10655 hypothetical protein X - Pyrococcus woesei (fragment). (154 aa)
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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