Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ackA | bglP | SMU_1978 | SMU_980 | Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Putative PTS system, beta-glucoside-specific EII component; Best Blastp Hit: gb|AAF89975.1|AF206272_1 (AF206272) beta-glucoside-specific EII permease [Streptococcus mutans]. | 0.513 |
| ackA | ccpA | SMU_1978 | SMU_1591 | Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Catabolite control protein A, CcpA; Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions. | 0.712 |
| ackA | citB | SMU_1978 | SMU_670 | Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Aconitate hydratase; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein. | 0.448 |
| ackA | citZ | SMU_1978 | SMU_671 | Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Citrate synthase; Best Blastp Hit: sp|Q59939|CISZ_STRMU CITRATE SYNTHASE >gi|1421813|gb|AAC44825.1| (U62799) citrate synthase [Streptococcus mutans]. | 0.584 |
| ackA | eno | SMU_1978 | SMU_1247 | Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Putative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity). Binds plasminogen and human salivary mucin MG2 when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity that may help the dissemination through oral tissues and entrance into the blood stream; Belongs to the enolase family. | 0.654 |
| ackA | gapN | SMU_1978 | SMU_676 | Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Best Blastp Hit: sp|Q59931|GAPN_STRMU NADP-DEPENDENT GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (NON-PHOSPHORYLATING GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE) (GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE [NADP+]) (TRIOSEPHOSPHATE DEHYDROGENASE) >gi|2117515|pir||A57151 glyceraldehyde-3-phosphate dehydrogenase (NADP+) (EC 1.2.1.9) - Streptococcus mutans >gi|5822059|pdb|1EUH|A Chain A, Apo Form Of A Nadp Dependent Aldehyde Dehydrogenase From Streptococcus Mutans >gi|5822060|pdb|1EUH|B Chain B, Apo Form Of A Nadp Dependent Aldehyde Dehydrogenase From Streptococcus Mutans >gi|5822061|pdb|1EUH|C [...] | 0.512 |
| ackA | glk | SMU_1978 | SMU_542 | Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Putative glucose kinase; Best Blastp Hit: pir||T44787 glucokinase (EC 2.7.1.2) [imported] - Bacillus megaterium >gi|2274867|emb|CAA03848.1| (AJ000005) glucose kinase [Bacillus megaterium]. | 0.417 |
| ackA | pfk | SMU_1978 | SMU_1191 | Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.585 |
| ackA | pgk | SMU_1978 | SMU_361 | Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Phosphoglycerate kinase; Best Blastp Hit: sp|Q9Z5C4|PGK_STAAU PHOSPHOGLYCERATE KINASE >gi|4490614|emb|CAB38646.1| (AJ133520) phosphoglycerate kinase [Staphylococcus aureus]; Belongs to the phosphoglycerate kinase family. | 0.726 |
| ackA | ptsG | SMU_1978 | SMU_2047 | Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Putative PTS system, glucose-specific IIABC component; Best Blastp Hit: gb|AAD00281.1| (U78600) putative ptsG## protein [Streptococcus mutans]. | 0.602 |
| ackA | pttB | SMU_1978 | SMU_2038 | Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Best Blastp Hit: pir||B82263 PTS system, trehalose-specific IIBC component VC0910 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9655367|gb|AAF94072.1| (AE004175) PTS system, trehalose-specific IIBC component [Vibrio cholerae]. | 0.515 |
| ahpC | eno | SMU_764 | SMU_1247 | Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Putative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity). Binds plasminogen and human salivary mucin MG2 when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity that may help the dissemination through oral tissues and entrance into the blood stream; Belongs to the enolase family. | 0.445 |
| ahpC | gapN | SMU_764 | SMU_676 | Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Best Blastp Hit: sp|Q59931|GAPN_STRMU NADP-DEPENDENT GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (NON-PHOSPHORYLATING GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE) (GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE [NADP+]) (TRIOSEPHOSPHATE DEHYDROGENASE) >gi|2117515|pir||A57151 glyceraldehyde-3-phosphate dehydrogenase (NADP+) (EC 1.2.1.9) - Streptococcus mutans >gi|5822059|pdb|1EUH|A Chain A, Apo Form Of A Nadp Dependent Aldehyde Dehydrogenase From Streptococcus Mutans >gi|5822060|pdb|1EUH|B Chain B, Apo Form Of A Nadp Dependent Aldehyde Dehydrogenase From Streptococcus Mutans >gi|5822061|pdb|1EUH|C [...] | 0.441 |
| ahpC | tpx | SMU_764 | SMU_924 | Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. | 0.815 |
| aldB | alsS | SMU_1451 | SMU_1452 | Best Blastp Hit: emb|CAA57941.1| (X82620) alpha-acetolactate decarboxylase [Lactococcus lactis]. | Alpha-acetolactate synthase; Best Blastp Hit: gb|AAA25161.1| (L16975) alpha-acetolactate synthase [Lactococcus lactis]; Belongs to the TPP enzyme family. | 0.999 |
| aldB | mutY | SMU_1451 | SMU_1865 | Best Blastp Hit: emb|CAA57941.1| (X82620) alpha-acetolactate decarboxylase [Lactococcus lactis]. | Putative A/G-specific DNA glycosylase; Adenine glycosylase active on G-A mispairs. | 0.645 |
| alsS | aldB | SMU_1452 | SMU_1451 | Alpha-acetolactate synthase; Best Blastp Hit: gb|AAA25161.1| (L16975) alpha-acetolactate synthase [Lactococcus lactis]; Belongs to the TPP enzyme family. | Best Blastp Hit: emb|CAA57941.1| (X82620) alpha-acetolactate decarboxylase [Lactococcus lactis]. | 0.999 |
| alsS | citB | SMU_1452 | SMU_670 | Alpha-acetolactate synthase; Best Blastp Hit: gb|AAA25161.1| (L16975) alpha-acetolactate synthase [Lactococcus lactis]; Belongs to the TPP enzyme family. | Aconitate hydratase; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein. | 0.464 |
| alsS | fabM | SMU_1452 | SMU_1746c | Alpha-acetolactate synthase; Best Blastp Hit: gb|AAA25161.1| (L16975) alpha-acetolactate synthase [Lactococcus lactis]; Belongs to the TPP enzyme family. | Putative enoyl-CoA hydratase; Catalyzes the isomerization of trans-2-decenoyl-ACP to cis-3- decenoyl-ACP (By similarity). Required for survival at low pH. | 0.454 |
| alsS | gapN | SMU_1452 | SMU_676 | Alpha-acetolactate synthase; Best Blastp Hit: gb|AAA25161.1| (L16975) alpha-acetolactate synthase [Lactococcus lactis]; Belongs to the TPP enzyme family. | Best Blastp Hit: sp|Q59931|GAPN_STRMU NADP-DEPENDENT GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (NON-PHOSPHORYLATING GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE) (GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE [NADP+]) (TRIOSEPHOSPHATE DEHYDROGENASE) >gi|2117515|pir||A57151 glyceraldehyde-3-phosphate dehydrogenase (NADP+) (EC 1.2.1.9) - Streptococcus mutans >gi|5822059|pdb|1EUH|A Chain A, Apo Form Of A Nadp Dependent Aldehyde Dehydrogenase From Streptococcus Mutans >gi|5822060|pdb|1EUH|B Chain B, Apo Form Of A Nadp Dependent Aldehyde Dehydrogenase From Streptococcus Mutans >gi|5822061|pdb|1EUH|C [...] | 0.541 |
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