STRINGSTRING
gtfC gtfC gyrA gyrA gtfB gtfB covX covX covR covR gcrR gcrR sacB sacB dexA dexA gbpB gbpB gtfD gtfD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gtfCglucosyltransferase-SI; Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris; Belongs to the glycosyl hydrolase 70 family. (1455 aa)
gyrADNA gyrase A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (825 aa)
gtfBglucosyltransferase-I; Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris; Belongs to the glycosyl hydrolase 70 family. (1476 aa)
covXConserved hypothetical protein CovX (VicX); Best Blastp Hit: emb|CAB65440.1| (AJ012049) VicX protein [Streptococcus pneumoniae]. (267 aa)
covRPutative response regulator CovR; Best Blastp Hit: emb|CAB65451.1| (AJ012051) VicR protein [Streptococcus pyogenes]. (235 aa)
gcrRResponse regulator GcrR for glucan-binding protein C; Best Blastp Hit: dbj|BAA85986.1| (AB024522) gcrR [Streptococcus mutans]. (230 aa)
sacBLevansucrase precursor; Best Blastp Hit: sp|P11701|SACB_STRMU LEVANSUCRASE## PRECURSOR (BETA-D-FRUCTOFURANOSYL TRANSFERASE) (SUCROSE 6-FRUCTOSYL TRANSFERASE) >gi|79999|pir||B28551 levansucrase (EC 2.4.1.10) precursor - Streptococcus mutans (strain GS-5) >gi|153636|gb|AAA88584.1| (M18954) fructosyltransferase [Streptococcus mutans]; Belongs to the glycosyl hydrolase 68 family. (795 aa)
dexADextranase precursor; May play a role in sucrose-independent adherence to the pellicle-coated tooth surface; Belongs to the glycosyl hydrolase 66 family. (850 aa)
gbpBBest Blastp Hit: gb|AAD00288.1| (U78607) putative secreted protein [Streptococcus mutans]. (431 aa)
gtfDglucosyltransferase-S; Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris; Belongs to the glycosyl hydrolase 70 family. (1462 aa)
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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