STRINGSTRING
pgm pgm ascB ascB ldh ldh adh adh pykF pykF pfk pfk eno eno adhA adhA adhB adhB adhC adhC adhD adhD pckA pckA pdhC pdhC pdhD pdhD adhE adhE bgl bgl SMU_1867c SMU_1867c pgi pgi gapC gapC pgk pgk glk glk pmgY pmgY gapN gapN tpiA tpiA bglA bglA fbaA fbaA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pgmPutative phosphoglucomutase; Best Blastp Hit: emb|CAB96418.1| (AJ243290) phosphoglucomutase [Streptococcus thermophilus]. (571 aa)
ascB6-phospho-beta-glucosidase; Best Blastp Hit: gb|AAA69226.1| (U29579) 6-phospho-beta-glucosidase [Escherichia coli]; Belongs to the glycosyl hydrolase 1 family. (478 aa)
ldhLactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (328 aa)
adhBest Blastp Hit: gb|AAG07017.1|AE004783_2 (AE004783) alcohol dehydrogenase class III [Pseudomonas aeruginosa]; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (372 aa)
pykFPyruvate kinase; Best Blastp Hit: gb|AAF25804.1|AF172173_2 (AF172173) pyruvate kinase [Streptococcus thermophilus]. (500 aa)
pfk6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (337 aa)
enoPutative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity). Binds plasminogen and human salivary mucin MG2 when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity that may help the dissemination through oral tissues and entrance into the blood stream; Belongs to the enolase family. (432 aa)
adhAPutative acetoin dehydrogenase (TPP-dependent), E1 component alpha subunit; Best Blastp Hit: dbj|BAB04495.1| (AP001509) acetoin dehydrogenase (TPP-dependent) alpha chain [Bacillus halodurans]. (331 aa)
adhBPutative acetoin dehydrogenase (TPP-dependent), E1 component beta subunit; Best Blastp Hit: dbj|BAB04496.1| (AP001509) acetoin dehydrogenase (TPP-dependent) beta chain [Bacillus halodurans]. (337 aa)
adhCBest Blastp Hit: dbj|BAB04497.1| (AP001509) dihydrolipoamide S-acetyltransferase [Bacillus halodurans]. (455 aa)
adhDBest Blastp Hit: pir||I40794 dihydrolipoamide dehydrogenase (EC 1.8.1.4) - Clostridium magnum >gi|472330|gb|AAA21748.1| (L31844) dihydrolipoamide dehydrogenase [Clostridium magnum]. (581 aa)
pckABest Blastp Hit: pir||D72755 hypothetical protein APE0033 - Aeropyrum pernix (strain K1) >gi|5103421|dbj|BAA78942.1| (AP000058) 493aa long hypothetical protein [Aeropyrum pernix]. (546 aa)
pdhCPutative dihydrolipoamide acetyltransferase, E2 component; Best Blastp Hit: sp|O31550|ACOC_BACSU DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF ACETOIN CLEAVING SYSTEM (ACETOIN DEHYDROGENASE E2 COMPONENT) >gi|7433670|pir||F69581 acetoin dehydrogenase E2 component (dihydrolipoamide acetyltra) acoC - Bacillus subtilis >gi|2633132|emb|CAB12637.1| (Z99108) acetoin dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [Bacillus subtilis] >gi|2780393|dbj|BAA24294.1| (D78509) YfjI [Bacillus subtilis]. (417 aa)
pdhDBest Blastp Hit: dbj|BAB04498.1| (AP001509) dihydrolipoamide dehydrogenase [Bacillus halodurans]. (445 aa)
adhEBest Blastp Hit: emb|CAA04467.1| (AJ001008) Alcohol-acetaldehyde dehydrogenase [Lactococcus lactis]; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (889 aa)
bglPutative phospho-beta-glucosidase; Best Blastp Hit: pir||JE0395 phospho-beta-galactosidase I - Lactobacillus gasseri >gi|2114112|dbj|BAA20086.1| (AB003927) phospho-beta-galactosidase 1 [Lactobacillus gasseri]; Belongs to the glycosyl hydrolase 1 family. (477 aa)
SMU_1867cPutative alcohol dehydrogenase; Best Blastp Hit: gb|AAG09966.1|AF248037_1 (AF248037) alcohol dehydrogenase [Streptococcus agalactiae]. (349 aa)
pgiGlucose-6-phosphate isomerase; Best Blastp Hit: gb|AAD33517.1|AF132127_2 (AF132127) glucose-6-phosphate isomerase [Streptococcus mutans]. (449 aa)
gapCExtracellular glyceraldehyde-3-phosphate dehydrogenase; Best Blastp Hit: sp|P50467|G3P_STRPY GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE (GAPDH) (PLASMINOGEN-BINDING PROTEIN) (PLASMIN RECEPTOR) >gi|285385|pir||A42963 glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) - Streptococcus sp >gi|153763|gb|AAA26953.1| (M95569) plasmin receptor [Streptococcus pyogenes]. (337 aa)
pgkPhosphoglycerate kinase; Best Blastp Hit: sp|Q9Z5C4|PGK_STAAU PHOSPHOGLYCERATE KINASE >gi|4490614|emb|CAB38646.1| (AJ133520) phosphoglycerate kinase [Staphylococcus aureus]; Belongs to the phosphoglycerate kinase family. (398 aa)
glkPutative glucose kinase; Best Blastp Hit: pir||T44787 glucokinase (EC 2.7.1.2) [imported] - Bacillus megaterium >gi|2274867|emb|CAA03848.1| (AJ000005) glucose kinase [Bacillus megaterium]. (323 aa)
pmgYPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (230 aa)
gapNBest Blastp Hit: sp|Q59931|GAPN_STRMU NADP-DEPENDENT GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (NON-PHOSPHORYLATING GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE) (GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE [NADP+]) (TRIOSEPHOSPHATE DEHYDROGENASE) >gi|2117515|pir||A57151 glyceraldehyde-3-phosphate dehydrogenase (NADP+) (EC 1.2.1.9) - Streptococcus mutans >gi|5822059|pdb|1EUH|A Chain A, Apo Form Of A Nadp Dependent Aldehyde Dehydrogenase From Streptococcus Mutans >gi|5822060|pdb|1EUH|B Chain B, Apo Form Of A Nadp Dependent Aldehyde Dehydrogenase From Streptococcus Mutans >gi|5822061|pdb|1EUH|C [...] (475 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (252 aa)
bglAPutative beta-glucosidase; Best Blastp Hit: gb|AAF89979.1|AF206272_5 (AF206272) beta-glucosidase [Streptococcus mutans]; Belongs to the glycosyl hydrolase 1 family. (479 aa)
fbaABest Blastp Hit: dbj|BAB16889.1| (AB050113) class-II aldolase [Streptococcus bovis]. (293 aa)
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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