STRINGSTRING
gtfB gtfB gtfC gtfC pgm pgm ascB ascB phsG phsG glgA glgA glgD glgD glgC glgC glgB glgB pulA pulA glgP glgP malQ malQ amyA amyA ptcC ptcC ptcA ptcA ptcB ptcB bgl bgl scrK scrK scrA scrA scrB scrB sacB sacB treA treA pttB pttB dexA dexA SMU_2046c SMU_2046c ptsG ptsG pgi pgi SMU_322c SMU_322c glk glk gtfA gtfA gtfD gtfD bglA bglA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gtfBglucosyltransferase-I; Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris; Belongs to the glycosyl hydrolase 70 family. (1476 aa)
gtfCglucosyltransferase-SI; Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris; Belongs to the glycosyl hydrolase 70 family. (1455 aa)
pgmPutative phosphoglucomutase; Best Blastp Hit: emb|CAB96418.1| (AJ243290) phosphoglucomutase [Streptococcus thermophilus]. (571 aa)
ascB6-phospho-beta-glucosidase; Best Blastp Hit: gb|AAA69226.1| (U29579) 6-phospho-beta-glucosidase [Escherichia coli]; Belongs to the glycosyl hydrolase 1 family. (478 aa)
phsGGlycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (798 aa)
glgAPutative starch (bacterial glycogen) synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (476 aa)
glgDPutative glycogen biosynthesis protein GlgD; Best Blastp Hit: dbj|BAB04805.1| (AP001510) required for glycogen biosynthesis [Bacillus halodurans]. (377 aa)
glgCPutative glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (381 aa)
glgBPutative 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (628 aa)
pulAPutative pullulanase; Best Blastp Hit: prf||1808262A thermostable pullulanase [Bacillus stearothermophilus]; Belongs to the glycosyl hydrolase 13 family. (743 aa)
glgPPutative glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (758 aa)
malQBest Blastp Hit: sp|P29851|MALQ_STRPN 4-ALPHA-GLUCANOTRANSFERASE (AMYLOMALTASE) (DISPROPORTIONATING ENZYME) (D-ENZYME) >gi|153704|gb|AAA26923.1| (J01796) amylomaltase [Streptococcus pneumoniae]. (509 aa)
amyAIntracellular alpha-amylase; Best Blastp Hit: gb|AAC35010.1| (AF055987) intracellular a-amylase [Streptococcus mutans]. (486 aa)
ptcCPutative PTS system, cellobiose-specific IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (452 aa)
ptcABest Blastp Hit: sp|P46319|PTCA_BACSU PTS SYSTEM, CELLOBIOSE-SPECIFIC IIA COMPONENT (EIIA-CEL) (CELLOBIOSE-PERMEASE IIA COMPONENT) (PHOSPHOTRANSFERASE ENZYME II, A COMPONENT) (EIII-CEL) >gi|1361403|pir||S57761 probable cellobiose phosphotransferase enzyme III - Bacillus subtilis >gi|7434479|pir||D69651 PTS lichenan-specific enzyme IIA component licA - Bacillus subtilis >gi|895750|emb|CAA90287.1| (Z49992) putative cellobiose phosphotransferase enzyme III [Bacillus subtilis] >gi|1783268|dbj|BAA11745.1| (D83026) cellobiose phosphotransferase enzyme III [Bacillus subtilis] >gi|2636392|emb| [...] (103 aa)
ptcBBest Blastp Hit: pir||D82219 PTS system, cellobiose-specific IIB component VC1281 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9655767|gb|AAF94440.1| (AE004207) PTS system, cellobiose-specific IIB component [Vibrio cholerae]. (105 aa)
bglPutative phospho-beta-glucosidase; Best Blastp Hit: pir||JE0395 phospho-beta-galactosidase I - Lactobacillus gasseri >gi|2114112|dbj|BAA20086.1| (AB003927) phospho-beta-galactosidase 1 [Lactobacillus gasseri]; Belongs to the glycosyl hydrolase 1 family. (477 aa)
scrKPutative fructokinase; Best Blastp Hit: sp|Q07211|SCRK_STRMU FRUCTOKINASE >gi|287459|dbj|BAA02467.1| (D13175) fructokinase [Streptococcus mutans]. (293 aa)
scrAPutative PTS system, sucrose-specific IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in sucrose transport. (664 aa)
scrBBest Blastp Hit: sp|P13522|SCRB_STRMU SUCROSE-6-PHOSPHATE## HYDROLASE (SUCRASE) (INVERTASE) >gi|97999|pir||A43501 sucrose-6-phosphate hydrolase - Streptococcus mutans >gi|47259|emb|CAA35872.1| (X51507) sucrose-6-phosphate hydrolase [Streptococcus mutans] >gi|153804|gb|AAA26972.1| (M36849) sucrose-6-phosphate hydrolase [Streptococcus mutans]. (479 aa)
sacBLevansucrase precursor; Best Blastp Hit: sp|P11701|SACB_STRMU LEVANSUCRASE## PRECURSOR (BETA-D-FRUCTOFURANOSYL TRANSFERASE) (SUCROSE 6-FRUCTOSYL TRANSFERASE) >gi|79999|pir||B28551 levansucrase (EC 2.4.1.10) precursor - Streptococcus mutans (strain GS-5) >gi|153636|gb|AAA88584.1| (M18954) fructosyltransferase [Streptococcus mutans]; Belongs to the glycosyl hydrolase 68 family. (795 aa)
treAPutative trehalose-6-phosphate hydrolase TreA; Best Blastp Hit: gb|AAB65079.1| (U35633) dextran glucosidase DexS [Streptococcus suis]. (542 aa)
pttBBest Blastp Hit: pir||B82263 PTS system, trehalose-specific IIBC component VC0910 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9655367|gb|AAF94072.1| (AE004175) PTS system, trehalose-specific IIBC component [Vibrio cholerae]. (655 aa)
dexADextranase precursor; May play a role in sucrose-independent adherence to the pellicle-coated tooth surface; Belongs to the glycosyl hydrolase 66 family. (850 aa)
SMU_2046cConserved hypothetical protein. (273 aa)
ptsGPutative PTS system, glucose-specific IIABC component; Best Blastp Hit: gb|AAD00281.1| (U78600) putative ptsG## protein [Streptococcus mutans]. (729 aa)
pgiGlucose-6-phosphate isomerase; Best Blastp Hit: gb|AAD33517.1|AF132127_2 (AF132127) glucose-6-phosphate isomerase [Streptococcus mutans]. (449 aa)
SMU_322cBest Blastp Hit: dbj|BAA28714.1| (AB001562) glucose-1-phosphate uridylyltransferase [Streptococcus mutans]. (306 aa)
glkPutative glucose kinase; Best Blastp Hit: pir||T44787 glucokinase (EC 2.7.1.2) [imported] - Bacillus megaterium >gi|2274867|emb|CAA03848.1| (AJ000005) glucose kinase [Bacillus megaterium]. (323 aa)
gtfASucrose phosphorylase, GtfA; Intracellular catabolism of sucrose. Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris. (481 aa)
gtfDglucosyltransferase-S; Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris; Belongs to the glycosyl hydrolase 70 family. (1462 aa)
bglAPutative beta-glucosidase; Best Blastp Hit: gb|AAF89979.1|AF206272_5 (AF206272) beta-glucosidase [Streptococcus mutans]; Belongs to the glycosyl hydrolase 1 family. (479 aa)
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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