STRINGSTRING
oadB oadB pycB pycB SMU_1043c SMU_1043c ldh ldh pykF pykF adhA adhA adhB adhB adhC adhC adhD adhD SMU_1323 SMU_1323 mleS mleS leuA leuA pckA pckA pdhC pdhC pdhD pdhD adhE adhE lguL lguL SMU_1725 SMU_1725 accA accA accD accD accC accC bccP bccP ackA ackA pfl pfl pfl2 pfl2 capP capP
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
oadBPutative oxaloacetate decarboxylase, sodium ion pump subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (373 aa)
pycBPutative pyruvate carboxylase/oxaloacetate decarboxylase, alpha subunit; Best Blastp Hit: sp|Q58628|PYCB_METJA PYRUVATE CARBOXYLASE SUBUNIT B (PYRUVIC CARBOXYLASE B) >gi|2129173|pir||F64453 oxaloacetate decarboxylase (EC 4.1.1.3) alpha chain MJ1231 [similarity] - Methanococcus jannaschii >gi|1591862|gb|AAB99233.1| (U67563) oxaloacetate decarboxylase alpha chain (oadA) [Methanococcus jannaschii]. (463 aa)
SMU_1043cPutative phosphotransacetylase; Best Blastp Hit: sp|P39646|PTA_BACSU PROBABLE PHOSPHATE ACETYLTRANSFERASE (PHOSPHOTRANSACETYLASE) (VEGETATIVE PROTEIN 43) (VEG43) >gi|2126977|pir||S39743 phosphotransacetylase pta - Bacillus subtilis >gi|580883|emb|CAA51644.1| (X73124) ipa-88d [Bacillus subtilis] >gi|2636302|emb|CAB15793.1| (Z99123) phosphotransacetylase [Bacillus subtilis]. (331 aa)
ldhLactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (328 aa)
pykFPyruvate kinase; Best Blastp Hit: gb|AAF25804.1|AF172173_2 (AF172173) pyruvate kinase [Streptococcus thermophilus]. (500 aa)
adhAPutative acetoin dehydrogenase (TPP-dependent), E1 component alpha subunit; Best Blastp Hit: dbj|BAB04495.1| (AP001509) acetoin dehydrogenase (TPP-dependent) alpha chain [Bacillus halodurans]. (331 aa)
adhBPutative acetoin dehydrogenase (TPP-dependent), E1 component beta subunit; Best Blastp Hit: dbj|BAB04496.1| (AP001509) acetoin dehydrogenase (TPP-dependent) beta chain [Bacillus halodurans]. (337 aa)
adhCBest Blastp Hit: dbj|BAB04497.1| (AP001509) dihydrolipoamide S-acetyltransferase [Bacillus halodurans]. (455 aa)
adhDBest Blastp Hit: pir||I40794 dihydrolipoamide dehydrogenase (EC 1.8.1.4) - Clostridium magnum >gi|472330|gb|AAA21748.1| (L31844) dihydrolipoamide dehydrogenase [Clostridium magnum]. (581 aa)
SMU_1323Conserved hypothetical protein; Best Blastp Hit: sp|P54501|YQGX_BACSU HYPOTHETICAL 23.2 KDA PROTEIN IN SODA-COMGA INTERGENIC REGION >gi|7446952|pir||A69958 conserved hypothetical protein yqgX - Bacillus subtilis >gi|1303871|dbj|BAA12527.1| (D84432) YqgX [Bacillus subtilis] >gi|2634913|emb|CAB14410.1| (Z99116) similar to hypothetical proteins [Bacillus subtilis]. (212 aa)
mleSMalolactic enzyme; Best Blastp Hit: pir||S43057 malolactic enzyme - Lactococcus lactis >gi|2130997|emb|CAA53589.1| (X75982) malolactic enzyme [Lactococcus lactis]. (540 aa)
leuAPutative 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (521 aa)
pckABest Blastp Hit: pir||D72755 hypothetical protein APE0033 - Aeropyrum pernix (strain K1) >gi|5103421|dbj|BAA78942.1| (AP000058) 493aa long hypothetical protein [Aeropyrum pernix]. (546 aa)
pdhCPutative dihydrolipoamide acetyltransferase, E2 component; Best Blastp Hit: sp|O31550|ACOC_BACSU DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF ACETOIN CLEAVING SYSTEM (ACETOIN DEHYDROGENASE E2 COMPONENT) >gi|7433670|pir||F69581 acetoin dehydrogenase E2 component (dihydrolipoamide acetyltra) acoC - Bacillus subtilis >gi|2633132|emb|CAB12637.1| (Z99108) acetoin dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [Bacillus subtilis] >gi|2780393|dbj|BAA24294.1| (D78509) YfjI [Bacillus subtilis]. (417 aa)
pdhDBest Blastp Hit: dbj|BAB04498.1| (AP001509) dihydrolipoamide dehydrogenase [Bacillus halodurans]. (445 aa)
adhEBest Blastp Hit: emb|CAA04467.1| (AJ001008) Alcohol-acetaldehyde dehydrogenase [Lactococcus lactis]; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (889 aa)
lguLBest Blastp Hit: sp|P44638|LGUL_HAEIN LACTOYLGLUTATHIONE LYASE (METHYLGLYOXALASE) (ALDOKETOMUTASE) (GLYOXALASE I) (GLX I) (KETONE-ALDEHYDE MUTASE) (S-D-LACTOYLGLUTATHIONE METHYLGLYOXAL LYASE) >gi|1074352|pir||I64147 lactoylglutathione lyase (EC 4.4.1.5) - Haemophilus influenzae >gi|1573292|gb|AAC21986.1| (U32717) lactoylglutathione lyase (gloA) [Haemophilus influenzae Rd]. (130 aa)
SMU_1725Putative acylphosphatase; Best Blastp Hit: pir||G72240 hypothetical protein TM1564 - Thermotoga maritima (strain MSB8) >gi|4982131|gb|AAD36630.1|AE001801_17 (AE001801) acylphosphatase, putative [Thermotoga maritima]. (92 aa)
accAPutative acetyl-CoA carboxylase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (256 aa)
accDPutative acetyl-CoA carboxylase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (288 aa)
accCPutative acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (456 aa)
bccPPutative biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (153 aa)
ackAPutative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (399 aa)
pflPyruvate formate-lyase; Best Blastp Hit: sp|Q59934|PFL_STRMU FORMATE ACETYLTRANSFERASE (PYRUVATE FORMATE-LYASE) >gi|1129082|dbj|BAA09085.1| (D50491) Pyruvate formate-lyase [Streptococcus mutans]. (775 aa)
pfl2Best Blastp Hit: sp|P75793|PFLF_ECOLI PUTATIVE FORMATE ACETYLTRANSFERASE 3 (PYRUVATE FORMATE-LYASE 3) >gi|7427871|pir||G64819 probable formate C-acetyltransferase (EC 2.3.1.54) - Escherichia coli >gi|1787044|gb|AAC73910.1| (AE000184) putative formate acetyltransferase [Escherichia coli] >gi|4062397|dbj|BAA35511.1| (D90720) Formate acetyltransferase 2 (EC 2.3.1.54) (pyruvate formate-lyase 2). [Escherichia coli]. (818 aa)
capPPutative phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (907 aa)
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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