STRINGSTRING
SMU_1043c SMU_1043c glyA glyA SMU_118c SMU_118c adh adh pfk pfk eno eno serB serB serA serA serC serC ackA ackA pmgY pmgY capP capP fbaA fbaA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
SMU_1043cPutative phosphotransacetylase; Best Blastp Hit: sp|P39646|PTA_BACSU PROBABLE PHOSPHATE ACETYLTRANSFERASE (PHOSPHOTRANSACETYLASE) (VEGETATIVE PROTEIN 43) (VEG43) >gi|2126977|pir||S39743 phosphotransacetylase pta - Bacillus subtilis >gi|580883|emb|CAA51644.1| (X73124) ipa-88d [Bacillus subtilis] >gi|2636302|emb|CAB15793.1| (Z99123) phosphotransacetylase [Bacillus subtilis]. (331 aa)
glyAPutative serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (420 aa)
SMU_118cPutative esterase; Serine hydrolase involved in the detoxification of formaldehyde. (280 aa)
adhBest Blastp Hit: gb|AAG07017.1|AE004783_2 (AE004783) alcohol dehydrogenase class III [Pseudomonas aeruginosa]; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (372 aa)
pfk6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (337 aa)
enoPutative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity). Binds plasminogen and human salivary mucin MG2 when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity that may help the dissemination through oral tissues and entrance into the blood stream; Belongs to the enolase family. (432 aa)
serBBest Blastp Hit: pir||T36772 probable phosphoserine phosphatase - Streptomyces coelicolor >gi|5525060|emb|CAB50876.1| (AL096844) putative phosphoserine phosphatase [Streptomyces coelicolor A3(2)]. (215 aa)
serABest Blastp Hit: sp|Q58424|SERA_METJA D-3-PHOSPHOGLYCERATE DEHYDROGENASE (PGDH) >gi|2129189|pir||A64427 phosphoglycerate dehydrogenase (EC 1.1.1.95) - Methanococcus jannaschii >gi|1591676|gb|AAB99020.1| (U67544) phosphoglycerate dehydrogenase (serA) [Methanococcus jannaschii]; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (393 aa)
serCPutative phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (363 aa)
ackAPutative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (399 aa)
pmgYPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (230 aa)
capPPutative phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (907 aa)
fbaABest Blastp Hit: dbj|BAB16889.1| (AB050113) class-II aldolase [Streptococcus bovis]. (293 aa)
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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