STRINGSTRING
krpS krpS glyA glyA pykF pykF pfk pfk ilvE ilvE rpiA rpiA eno eno SMU_1261c SMU_1261c hisI hisI hisF hisF hisA hisA hisH hisH hisB hisB serB serB hisD hisD hisG hisG hisZ hisZ hisC hisC SMU_1291c SMU_1291c leuD leuD leuC leuC leuB leuB leuA leuA alsS alsS metA metA SMU_1486c SMU_1486c cysE cysE metK metK pfs pfs serA serA serC serC metC metC metB metB SMU_1721c SMU_1721c akh akh yfbQ yfbQ aroG aroG aroH aroH Peptidase Peptidase proC proC ilvD ilvD prs prs ilvB ilvB ilvH ilvH ilvC ilvC ilvA ilvA SMU_24 SMU_24 tkt tkt dapH dapH SMU_318 SMU_318 argG argG argH argH SMU_352 SMU_352 gapC gapC pgk pgk glnA glnA gltA gltA gltB gltB proB proB proA proA luxS luxS cysK cysK trpE trpE trpG trpG trpD trpD trpC trpC trpF trpF trpB trpB trpA trpA argF argF pmgY pmgY argC argC argJ argJ argB argB argD argD citB citB citZ citZ idh idh thrC thrC tpiA tpiA aroD aroD aroE aroE aroB aroB aroC aroC SMU_781 SMU_781 aroA aroA aroK aroK pheA pheA metE metE SMU_874 SMU_874 dapB dapB SMU_965 SMU_965 thrB thrB asd asd fbaA fbaA dapA dapA
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krpSPutative phosphoribosylpyrophosphate synthetase, PRPP synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (326 aa)
glyAPutative serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (420 aa)
pykFPyruvate kinase; Best Blastp Hit: gb|AAF25804.1|AF172173_2 (AF172173) pyruvate kinase [Streptococcus thermophilus]. (500 aa)
pfk6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (337 aa)
ilvEBest Blastp Hit: gb|AAF34406.1|AF164204_1 (AF164204) branched-chain amino acid aminotransferase [Lactococcus lactis subsp. cremoris] >gi|7620382|gb|AAF64593.1|AF169649_1 (AF169649) branched-chain aminotransferase IlvE [Lactococcus lactis]. (341 aa)
rpiAPutative ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (225 aa)
enoPutative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity). Binds plasminogen and human salivary mucin MG2 when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity that may help the dissemination through oral tissues and entrance into the blood stream; Belongs to the enolase family. (432 aa)
SMU_1261cPutative phosphoribosyl-ATP pyrophosphohydrolase; Best Blastp Hit: pir||D75482 phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase - Deinococcus radiodurans (strain R1) >gi|6458442|gb|AAF10312.1|AE001929_5 (AE001929) phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase [Deinococcus radiodurans]. (61 aa)
hisIPutative phosphoribosyl-ATP pyrophosphatase / phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (109 aa)
hisFPutative imidazoleglycerol-phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa)
hisABest Blastp Hit: gb|AAF05093.1|AF150930_2 (AF150930) phosphoribosyl formimino-5-aminoimidazole isomerase [Thermoanaerobacter ethanolicus]. (239 aa)
hisHPutative glutamine amidotransferase HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (201 aa)
hisBBest Blastp Hit: dbj|BAB07300.1| (AP001519) imidazoleglycerol-phosphate dehydratase [Bacillus halodurans]. (194 aa)
serBBest Blastp Hit: pir||T36772 probable phosphoserine phosphatase - Streptomyces coelicolor >gi|5525060|emb|CAB50876.1| (AL096844) putative phosphoserine phosphatase [Streptomyces coelicolor A3(2)]. (215 aa)
hisDPutative histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (427 aa)
hisGPutative ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (215 aa)
hisZPutative histidyl-tRNA synthetase; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (320 aa)
hisCBest Blastp Hit: sp|Q02135|HIS8_LACLA HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMIDAZOLE ACETOL-PHOSPHATE TRANSAMINASE) >gi|2565139|gb|AAB81901.1| (U92974) HisC [Lactococcus lactis]; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (349 aa)
SMU_1291cBest Blastp Hit: pir||H81450 chorismate mutase (EC 5.4.99.5) / prephenate dehydratase (EC 4.2.1.51) Cj0316 [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6967790|emb|CAB72783.1| (AL139074) chorismate mutaseprephenate dehydratase [Campylobacter jejuni]. (90 aa)
leuDPutative 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (196 aa)
leuCPutative 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (461 aa)
leuBPutative 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. (344 aa)
leuAPutative 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (521 aa)
alsSAlpha-acetolactate synthase; Best Blastp Hit: gb|AAA25161.1| (L16975) alpha-acetolactate synthase [Lactococcus lactis]; Belongs to the TPP enzyme family. (559 aa)
metAPutative homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (314 aa)
SMU_1486cBest Blastp Hit: pir||E72330 conserved hypothetical protein - Thermotoga maritima (strain MSB8) >gi|4981334|gb|AAD35886.1|AE001748_2 (AE001748) conserved hypothetical protein [Thermotoga maritima]; Belongs to the PHP hydrolase family. HisK subfamily. (244 aa)
cysEPutative serine acetyltransferase; Best Blastp Hit: gb|AAC33374.1| (AF001780) NifP [Cyanothece PCC8801]. (222 aa)
metKPutative S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (397 aa)
pfsPutative MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (231 aa)
serABest Blastp Hit: sp|Q58424|SERA_METJA D-3-PHOSPHOGLYCERATE DEHYDROGENASE (PGDH) >gi|2129189|pir||A64427 phosphoglycerate dehydrogenase (EC 1.1.1.95) - Methanococcus jannaschii >gi|1591676|gb|AAB99020.1| (U67544) phosphoglycerate dehydrogenase (serA) [Methanococcus jannaschii]; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (393 aa)
serCPutative phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (363 aa)
metCBest Blastp Hit: sp|Q08432|PATB_BACSU PUTATIVE AMINOTRANSFERASE B >gi|421526|pir||S32934 aminotransferase patB - Bacillus subtilis >gi|1934779|emb|CAB07910.1| (Z93933) aminotransferase [Bacillus subtilis] >gi|1934787|emb|CAB07924.1| (Z93934) aminotransferase [Bacillus subtilis] >gi|2231218|gb|AAB61979.1| (U63302) PatB [Bacillus subtilis] >gi|2635640|emb|CAB15133.1| (Z99120) aminotransferase [Bacillus subtilis]. (387 aa)
metBPutative cystathionine gamma-synthase; Best Blastp Hit: pir||G64047 cystathionine gamma-lyase homolog - Haemophilus influenzae (strain Rd KW20) >gi|1573037|gb|AAC21764.1| (U32694) cystathionine gamma-synthase (metB) [Haemophilus influenzae Rd] 4.4.1.1 cystathionine gamma-lyase or cystathionine beta-lyases 4.4.8.1. (364 aa)
SMU_1721cPutative diaminopimelate decarboxylase; Best Blastp Hit: sp|P31851|TABA_PSESZ TABA PROTEIN >gi|281610|pir||S27649 tabA protein - Pseudomonas syringae >gi|151571|gb|AAB41802.1| (M88485) Homology with E.coli and P.aeruginosa lysA gene; product of unknown function; putative [Pseudomonas syringae]. (416 aa)
akhPutative aspartokinase; Best Blastp Hit: sp|P94417|AK3_BACSU PROBABLE ASPARTOKINASE (ASPARTATE KINASE) >gi|7474867|pir||A69763 homoserine dehydrogenase homolog yclM - Bacillus subtilis >gi|1805449|dbj|BAA09011.1| (D50453) homologue of aspartokinase 2 alpha and beta subunits LysC of B. subtilis [Bacillus subtilis] >gi|2632680|emb|CAB12187.1| (Z99106) similar to homoserine dehydrogenase [Bacillus subtilis]; Belongs to the aspartokinase family. (452 aa)
yfbQPutative aminotransferase; Best Blastp Hit: sp|P71348|YFBQ_HAEIN PROBABLE AMINOTRANSFERASE HI0286 >gi|1573250|gb|AAC21948.1| (U32714) aminotransferase## [Haemophilus influenzae Rd]. (405 aa)
aroGPutative DAHP synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (344 aa)
aroHPutative DAHP synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (343 aa)
PeptidasePutative peptidase, AtmC; Best Blastp Hit: pir||E75327 ArgE/DapE/Acy1 family protein - Deinococcus radiodurans (strain R1) >gi|6459799|gb|AAF11560.1|AE002038_9 (AE002038) ArgE/DapE/Acy1 family protein [Deinococcus radiodurans]. (457 aa)
proCPutative pyrroline carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (256 aa)
ilvDBest Blastp Hit: sp|P74689|ILVD_SYNY3 DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|7436855|pir||S76895 hypothetical protein - Synechocystis sp. (strain PCC 6803) >gi|1653897|dbj|BAA18807.1| (D90917) dihydroxyacid dehydratase [Synechocystis sp.]; Belongs to the IlvD/Edd family. (571 aa)
prsPhosphoribosyl pyrophosphate synthetase (PRPP synthetase); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (322 aa)
ilvBBest Blastp Hit: sp|Q02137|ILVB_LACLA ACETOLACTATE SYNTHASE LARGE SUBUNIT (AHAS) (ACETOHYDROXY-ACID SYNTHASE LARGE SUBUNIT) (ALS) >gi|486730|pir||S35138 acetolactate synthase (EC 4.1.3.18) - Lactococcus lactis subsp. lactis >gi|2565157|gb|AAB81919.1| (U92974) IlvB [Lactococcus lactis]. (567 aa)
ilvHBest Blastp Hit: sp|Q02140|ILVH_LACLA ACETOLACTATE SYNTHASE SMALL SUBUNIT (AHAS) (ACETOHYDROXY-ACID SYNTHASE SMALL SUBUNIT) (ALS) >gi|486731|pir||S35139 probable acetolactate synthase (EC 4.1.3.18) small chain - Lactococcus lactis subsp. lactis >gi|2565158|gb|AAB81920.1| (U92974) IlvN [Lactococcus lactis]. (160 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (340 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (416 aa)
SMU_24Best Blastp Hit: gb|AAF06954.1|AF146529_1 (AF146529) aromatic amino acid aminotransferase [Lactococcus lactis subsp. cremoris]. (391 aa)
tktTransketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (658 aa)
dapHPutative tetrahydrodipicolinate succinylase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (232 aa)
SMU_318Putative hippurate hydrolase; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate. (376 aa)
argGBest Blastp Hit: dbj|BAB06906.1| (AP001518) argininosuccinate synthase (citrulline-asparate ligase) [Bacillus halodurans]; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (396 aa)
argHArgininosuccinate lyase; Best Blastp Hit: dbj|BAB06905.1| (AP001518) argininosuccinate lyase [Bacillus halodurans]. (460 aa)
SMU_352Putative ribulose-phosphate-3-epimerase; Best Blastp Hit: dbj|BAB06221.1| (AP001515) unknown conserved protein [Bacillus halodurans]; Belongs to the ribulose-phosphate 3-epimerase family. (219 aa)
gapCExtracellular glyceraldehyde-3-phosphate dehydrogenase; Best Blastp Hit: sp|P50467|G3P_STRPY GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE (GAPDH) (PLASMINOGEN-BINDING PROTEIN) (PLASMIN RECEPTOR) >gi|285385|pir||A42963 glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) - Streptococcus sp >gi|153763|gb|AAA26953.1| (M95569) plasmin receptor [Streptococcus pyogenes]. (337 aa)
pgkPhosphoglycerate kinase; Best Blastp Hit: sp|Q9Z5C4|PGK_STAAU PHOSPHOGLYCERATE KINASE >gi|4490614|emb|CAB38646.1| (AJ133520) phosphoglycerate kinase [Staphylococcus aureus]; Belongs to the phosphoglycerate kinase family. (398 aa)
glnABest Blastp Hit: gb|AAC44800.1| (U61271) glutamine synthetase type 1 [Streptococcus agalactiae]. (448 aa)
gltABest Blastp Hit: dbj|BAB05447.1| (AP001513) glutamate synthase (large subunit) [Bacillus halodurans]. (1505 aa)
gltBNADPH-dependent glutamate synthase (small subunit); Best Blastp Hit: dbj|BAA12742.1| (D85230) small subunit of NADH-dependent glutamate synthase [Plectonema boryanum]. (478 aa)
proBPutative gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (269 aa)
proAPutative gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (416 aa)
luxSPutative autoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (160 aa)
cysKPutative cysteine synthetase A; Best Blastp Hit: dbj|BAA88310.1| (AB028865) O-acetylserine lyase [Streptococcus suis]; Belongs to the cysteine synthase/cystathionine beta- synthase family. (308 aa)
trpEPutative anthranilate synthase, alpha subunit; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and h [...] (453 aa)
trpGPutative anthranilate synthase, beta subunit; Best Blastp Hit: sp|Q02003|TRPG_LACLA ANTHRANILATE SYNTHASE COMPONENT II (GLUTAMINE AMIDO-TRANSFERASE) >gi|421418|pir||S35125 anthranilate synthase (EC 4.1.3.27) beta chain - Lactococcus lactis subsp. lactis >gi|551880|gb|AAA25224.1| (M87483) anthranilate synthase beta subunit [Lactococcus lactis]. (187 aa)
trpDPutative phosphoribosyl anthranilate transferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (335 aa)
trpCBest Blastp Hit: sp|Q01999|TRPC_LACLA INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS) >gi|421422|pir||S35127 indole-3-glycerol-phosphate synthase (EC 4.1.1.48) - Lactococcus lactis subsp. lactis >gi|149519|gb|AAA25226.1| (M87483) indoleglycerol phosphate synthase [Lactococcus lactis]; Belongs to the TrpC family. (255 aa)
trpFBest Blastp Hit: sp|Q02002|TRPF_LACLA N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE (PRAI) >gi|421427|pir||S35128 phosphoribosylanthranilate isomerase (EC 5.3.1.24) - Lactococcus lactis subsp. lactis >gi|149520|gb|AAA25227.1| (M87483) phosphoribosyl anthranilate isomerase [Lactococcus lactis]; Belongs to the TrpF family. (193 aa)
trpBPutative tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (403 aa)
trpAPutative tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (260 aa)
argFPutative ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (326 aa)
pmgYPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (230 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (340 aa)
argJPutative ornithine acetyltransferase/N-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (397 aa)
argBPutative acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (245 aa)
argDBest Blastp Hit: dbj|BAB06616.1| (AP001517) N-acetylornithine aminotransferase [Bacillus halodurans]; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (379 aa)
citBAconitate hydratase; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein. (888 aa)
citZCitrate synthase; Best Blastp Hit: sp|Q59939|CISZ_STRMU CITRATE SYNTHASE >gi|1421813|gb|AAC44825.1| (U62799) citrate synthase [Streptococcus mutans]. (372 aa)
idhBest Blastp Hit: sp|Q59940|IDH_STRMU ISOCITRATE DEHYDROGENASE [NADP] (OXALOSUCCINATE DECARBOXYLASE) (IDH) (NADP+-SPECIFIC ICDH) (IDP) >gi|1421814|gb|AAC44826.1| (U62799) isocitrate dehydrogenase [Streptococcus mutans]. (393 aa)
thrCPutative threonine synthase; Best Blastp Hit: sp|Q9ZMX5|THRC_HELPJ THREONINE SYNTHASE >gi|7437080|pir||A71975 threonine synthase - Helicobacter pylori (strain J99) >gi|4154598|gb|AAD05671.1| (AE001448) THREONINE SYNTHASE [Helicobacter pylori J99]. (494 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (252 aa)
aroDPutative 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (225 aa)
aroEPutative shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (289 aa)
aroBPutative 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (355 aa)
aroCPutative chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (388 aa)
SMU_781Best Blastp Hit: sp|P43901|TYRA_LACLA PREPHENATE DEHYDROGENASE (PDH) >gi|1075739|pir||S52579 prephenate dehydrogenase (EC 1.3.1.12) - Lactococcus lactis >gi|683582|emb|CAA55179.1| (X78413) prephenate dehydrogenase [Lactococcus lactis]. (368 aa)
aroA5-enolpyruvylshikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (427 aa)
aroKPutative shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (158 aa)
pheABest Blastp Hit: sp|P43909|PHEA_LACLA PREPHENATE DEHYDRATASE (PDT) >gi|1075738|pir||S52582 prephenate dehydratase (EC 4.2.1.51) - Lactococcus lactis >gi|683585|emb|CAA55182.1| (X78413) prephenate dehydratase [Lactococcus lactis]. (274 aa)
metEPutative homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (745 aa)
SMU_874Conserved hypothetical protein; Best Blastp Hit: dbj|BAB05348.1| (AP001512) unknown conserved protein [Bacillus halodurans]. (618 aa)
dapBPutative dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (255 aa)
SMU_965Best Blastp Hit: sp|P52985|DHOM_LACLA HOMOSERINE DEHYDROGENASE (HDH) >gi|2117450|pir||JC6049 homoserine dehydrogenase (EC 1.1.1.3) - Lactococcus lactis >gi|1255939|emb|CAA65713.1| (X96988) hom [Lactococcus lactis]. (428 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (288 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (358 aa)
fbaABest Blastp Hit: dbj|BAB16889.1| (AB050113) class-II aldolase [Streptococcus bovis]. (293 aa)
dapAPutative dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (293 aa)
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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