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ygfZ | Folate-dependent protein involved in synthesis and repair of FeS clusters YgfZ; Belongs to the GcvT family. (318 aa) | ||||
bolA | Global transcriptional regulator BolA; Belongs to the BolA/IbaG family. (106 aa) | ||||
SO_1846 | Uncharacterized protein. (298 aa) | ||||
SO_1848 | Uncharacterized protein. (252 aa) | ||||
SO_1849 | Uncharacterized protein. (179 aa) | ||||
SO_1850 | DnaJ domain protein. (94 aa) | ||||
iscR | Transcriptional repressor of iron-sulfur cluster assembly genes IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. (153 aa) | ||||
iscS | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (404 aa) | ||||
iscU | FeS cluster assembly scaffold protein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. (127 aa) | ||||
iscA | FeS cluster assembly acessory protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. (107 aa) | ||||
hscB | Co-chaperone Hsc20 HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. (174 aa) | ||||
hscA | Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. (620 aa) | ||||
fdx | Ferredoxin 2Fe-2S type ISC system Fdx. (111 aa) | ||||
iscX | FeS assembly protein IscX. (65 aa) | ||||
grxD | Monothiol glutaredoxin GrxD; Belongs to the glutaredoxin family. Monothiol subfamily. (110 aa) | ||||
djlA | DnaK co-chaperone DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. (262 aa) | ||||
cyaY | Iron donor for FeS cluster assembly CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. (109 aa) | ||||
nfuA | Iron-sulfur cluster biogenesis scaffold protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (192 aa) |