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| | argG | Argininosuccinate synthase ArgG; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (407 aa) |
| | argH | Argininosuccinate lyase ArgH. (455 aa) |
| | aroK | Shikimate kinase AroK; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (171 aa) |
| | aroB | 3-dehydroquinate synthase AroB; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (359 aa) |
| | gph | 2-phosphoglycolate phosphatase Gph; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (227 aa) |
| | ilvE | Branched-chain-amino-acid transaminase IlvE. (363 aa) |
| | SO_0364 | Phosphotransferase enzyme family protein. (346 aa) |
| | ubiA | 4-hydroxybenzoate octaprenyltransferase UbiA; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (286 aa) |
| | nosD | ABC-type copper transport system substrate-binding component NosD. (424 aa) |
| | ubiD | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase UbiD; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. (488 aa) |
| | accB | acetyl-CoA carboxylase biotin carboxyl carrier protein AccB; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (152 aa) |
| | aroQ | 3-dehydroquinate dehydratase type II AroQ; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (146 aa) |
| | SO_0559 | MaoC domain protein. (276 aa) |
| | SO_0585 | D-isomer specific 2-hydroxyacid dehydrogenase family protein. (311 aa) |
| | argD | Bifunctional acetylornithine aminotransferase/succinyl-diaminopimelate aminotransferase/succinylornithine transaminase ArgD; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (405 aa) |
| | SO_0640 | Putative NAD(P)H quinone oxidoreductase PIG3 family. (332 aa) |
| | SO_0735 | Predicted inner membrane protein. (316 aa) |
| | glsF | Ferredoxin-dependent glutamate synthase GlsF; Belongs to the glutamate synthase family. (496 aa) |
| | aroG | Phospho-2-dehydro-3-deoxyheptonate aldolase phe-sensitive AroG; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (352 aa) |
| | argR | Arginine-responsive transcriptional repressor of arginine metabolism ArgR; Regulates arginine biosynthesis genes. (156 aa) |
| | ubiH | 2-octaprenyl-6-methoxyphenol hydroxylase UbiH. (407 aa) |
| | visC | FAD-dependent hydroxylase VisC. (407 aa) |
| | SO_0807 | Predicted phosphoribosyltransferase. (188 aa) |
| | metE | B12-independent 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase MetE; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (760 aa) |
| | serA | D-3-phosphoglycerate dehydrogenase SerA; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (409 aa) |
| | panC | Pantoate--beta-alanine ligase PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (281 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase PanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (264 aa) |
| | folK | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK. (162 aa) |
| | yheT | Peptidase S33 family YheT. (327 aa) |
| | e4pd | D-erythrose-4-phosphate dehydrogenase E4pd; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate. (338 aa) |
| | pgk | Phosphoglycerate kinase Pgk; Belongs to the phosphoglycerate kinase family. (391 aa) |
| | SO_0944 | Radical SAM protein TatD family-associated. (234 aa) |
| | SO_0954 | Acteyltransferase GNAT family. (139 aa) |
| | metH | B12-dependent 5-methyltetrahydrofolate--homocysteine methyltransferase MetH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1244 aa) |
| | cobT | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase CobT; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (350 aa) |
| | cobS | Cobalamin 5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (262 aa) |
| | cobU | Bifunctional cobinamide kinase/cobinamide phosphate guanylyltransferase CobU; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (201 aa) |
| | cobQ | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (510 aa) |
| | cobO | cob(I)alamin adenosyltransferase CobO; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (207 aa) |
| | proB | Glutamate 5-kinase ProB; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (372 aa) |
| | proA | Gamma-glutamyl phosphate reductase ProA; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (425 aa) |
| | dapB | Dihydrodipicolinate reductase DapB; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (270 aa) |
| | carA | Carbamoyl-phosphate synthase small subunit CarA; Belongs to the CarA family. (386 aa) |
| | carB | Carbamoyl-phosphate synthase large subunit CarB; Belongs to the CarB family. (1074 aa) |
| | lipA | Lipoic acid synthetase LipA; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (321 aa) |
| | ubiF | 2-octaprenyl-3-methyl-6-methoxy-14-benzoquinone hydroxylase UbiF. (404 aa) |
| | folP | Dihydropteroate synthase FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (277 aa) |
| | tpiA | Triosephosphate isomeraseTpiA; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (260 aa) |
| | serB | Phosphoserine phosphatase SerB. (330 aa) |
| | SO_1248 | Peptidase U32 family YhbV. (289 aa) |
| | SO_1250 | SCP-2 sterol transfer family protein. (176 aa) |
| | puuA | Gamma-glutamyl-putrescine synthase PuuA; Belongs to the glutamine synthetase family. (451 aa) |
| | folB | Dihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (116 aa) |
| | SO_1292 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK-like protein. (167 aa) |
| | cobD | Adenosylcobinamide-phosphate synthase CobD. (329 aa) |
| | mtnN | 5-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase MtnN; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (236 aa) |
| | gltB | NADPH-dependent glutamate synthase large subunit GltB. (1482 aa) |
| | pdxJ | Pyridoxal phosphate synthase PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (245 aa) |
| | acpS | Holo-(acyl-carrier protein) synthase AcpS; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (127 aa) |
| | aroF | Phospho-2-dehydro-3-deoxyheptonate aldolase tyr-sensitive AroF; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (363 aa) |
| | tyrA | Bifunctional chorismate mutase T/prephenate dehydrogenase TyrA. (379 aa) |
| | pheA | Multifunctional chorismate mutase P/prephenate dehydratase/DAHP synthetase PheA. (671 aa) |
| | yfjG | Lipid binding/transport family protein YfjG. (145 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase Dxs; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (622 aa) |
| | thiI | Thiazole biosynthesis/tRNA modification proteinThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (484 aa) |
| | SO_1538 | Isocitrate dehydrogenase NAD-dependent. (335 aa) |
| | SO_1566 | Acteyltransferase GNAT family. (169 aa) |
| | pfaB | Omega-3 polyunsaturated fatty acid synthase PfaB. (788 aa) |
| | queF | NADPH-dependent preQ0 reductase QueF; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). (286 aa) |
| | SO_1613 | Protein of unknown function DUF2789. (77 aa) |
| | yqcA | tRNA pseudouridine synthase C-associated flavoprotein YqcA. (154 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase DapD; Belongs to the transferase hexapeptide repeat family. (274 aa) |
| | uppS | Undecaprenyl diphosphate synthase UppS; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. (275 aa) |
| | fabZ | (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (154 aa) |
| | phhA | Phenylalanine-4-hydroxylase PhhA. (271 aa) |
| | phhB | Pterin-4-alpha-carbinolamine dehydratase PhhB. (112 aa) |
| | metA | Homoserine O-succinyltransferase MetA; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. (313 aa) |
| | oleA | Polyolefin biosynthetic pathway thiolase OleA; Involved in olefin biosynthesis. Catalyzes a non-decarboxylative head-to-head Claisen condensation of two acyl-CoA molecules, generating an (R)-2-alkyl-3-oxoalkanoate (By similarity). The S.oneidensis oleABCD genes produce 3,6,9,12,15,19,22,25,28- hentriacontanonaene, which may aid the cells in adapting to a sudden drop in temperature. (349 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa) |
| | fabV | Enoyl acyl-carrier-protein reductase FabV; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (400 aa) |
| | fabA | 3-hydroxydecanoyl-(acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (171 aa) |
| | dapA | Dihydrodipicolinate synthase DapA; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa) |
| | liuE | 3-hydroxymethylglutaryl-CoA lyase LiuE. (315 aa) |
| | liuB | methylcrotonyl-CoA carboxylase carboxyl transferase subunit LiuB. (535 aa) |
| | menA | 1,4-dihydroxy-2-naphthoate octaprenyltransferase MenA; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (291 aa) |
| | SO_1957 | Predicted periplasmic protein. (386 aa) |
| | SO_1988 | SAM-dependent methyltransferase type 11. (204 aa) |
| | apt | Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (183 aa) |
| | hisIE | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase HisIE; In the C-terminal section; belongs to the PRA-PH family. (211 aa) |
| | hisF | Imidazole glycerol phosphate synthase cyclase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase HisA. (245 aa) |
| | hisH | Imidazole glycerol phosphate synthase glutamine amidotransferase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (221 aa) |
| | hisB | Bifunctional imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase HisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. (363 aa) |
| | hisC | Histidinol-phosphate aminotransferase HisC; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (391 aa) |
| | hisD | Histidinol dehydrogenase HisD; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (438 aa) |
| | hisG | ATP phosphoribosyltransferase HisG; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (324 aa) |
| | lpxM | KDO 2-(lauroyl)-lipid IVA acyltransferase LpxM; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. (312 aa) |
| | queD | Queosine biosynthesis protein QueD. (291 aa) |
| | sdaA | L-serine ammonia-lyase SdaA; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa) |
| | cysE | Serine acetyltransferase CysE. (273 aa) |
| | ilvH | Acetolactate synthase III small subunit IlvH. (164 aa) |
| | ribC | 6,7-dimethyl-8-ribityllumazine synthase alpha subunit RibC. (206 aa) |
| | serS | seryl-tRNA synthetase SerS; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (428 aa) |
| | nadA | Quinolinate synthetase NadA; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (357 aa) |
| | gapA-2 | Glyceraldehyde-3-phosphate dehydrogenase (NAD+) GapA; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (426 aa) |
| | serC | Bifunctional 3-phosphoserine aminotransferase/phosphohydroxythreonine SerC; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (365 aa) |
| | ubiG | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (236 aa) |
| | thiH | Thiazole biosynthesis protein ThiH. (375 aa) |
| | thiG | Thiazole-phosphate synthase ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (254 aa) |
| | thiS | Sulphur carrier protein ThiS. (67 aa) |
| | thiDE | Bifunctional hydroxy-(phospho)methylpyrimidine kinase/thiamine-phosphate pyrophosphorylase ThiDE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (525 aa) |
| | thiC | Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (721 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase DapE; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (384 aa) |
| | queE | Queuosine biosynthesis radical activating enzyme QueE; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (222 aa) |
| | queC | Queuosine biosynthesis ATPase QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (238 aa) |
| | pabC | Aminodeoxychorismate lyase PabC. (269 aa) |
| | ppsA | Phosphoenolpyruvate synthase PpsA; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (789 aa) |
| | aroH | Phospho-2-dehydro-3-deoxyheptonate aldolase trp-sensitive AroH; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (354 aa) |
| | thiK | Predicted thiamine kinase ThiK. (379 aa) |
| | bioD | Dethiobiotin synthase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (231 aa) |
| | bioC | SAM-dependent methylase involved in biotin synthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. (275 aa) |
| | bioB | Biotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (350 aa) |
| | bioA | Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (461 aa) |
| | asnB | Asparagine synthase glutamine-hydrolyzing AsnB. (554 aa) |
| | fabF | 3-oxoacyl-(acyl-carrier-protein) synthase II FabF; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (412 aa) |
| | acpP | Acyl carrier protein AcpP; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (77 aa) |
| | fabD | Malonyl CoA-acyl carrier protein transacylase FabD. (308 aa) |
| | fabH | 3-oxoacyl-(acyl-carrier-protein) synthase III FabH; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (319 aa) |
| | plsX | phosphate:acyl-ACP acyltransferase PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (342 aa) |
| | ribA | GTP cyclohydrolase II RibA; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (203 aa) |
| | fabH-2 | 3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (354 aa) |
| | pdxH | Pyridoxamine-phosphate oxidase PdxH; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (212 aa) |
| | cysZ | Putative sulfate transporter CysZ; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family. (259 aa) |
| | SO_2901 | 3-oxoacyl-(acyl-carrier-protein) synthase III domain protein. (373 aa) |
| | cysK | Cysteine synthase CysK; Belongs to the cysteine synthase/cystathionine beta- synthase family. (322 aa) |
| | trpD | Anthranilate phosphoribosyltransferase TrpD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (347 aa) |
| | trpCF | Bifunctional indole-3-glycerolphosphate synthetase/phosphoribosylanthranilate isomerase TrpCF; Belongs to the TrpC family. (498 aa) |
| | trpB | Tryptophan synthase beta subunit TrpB; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (396 aa) |
| | trpA | Tryptophan synthase alpha subunit TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (278 aa) |
| | folC | Bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC; Belongs to the folylpolyglutamate synthase family. (431 aa) |
| | asd | Aspartate semialdehyde dehydrogenese Asd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (338 aa) |
| | pdxB | Erythronate-4-phosphate dehydrogenase PdxB; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. (376 aa) |
| | fabB | 3-oxoacyl-(acyl-carrier-protein) synthase I FabB; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (411 aa) |
| | aroC | Chorismate synthase AroC; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (364 aa) |
| | tgt | Queuine tRNA-ribosyltransferase Tgt; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to for [...] (374 aa) |
| | queA | S-adenosylmethionine:tRNA ribosyltransferase-isomerase QueA; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (345 aa) |
| | SO_3116 | Acyl carrier protein phosphodiesterase AcpH-like protein. (204 aa) |
| | wbpQ | Asparagine synthase glutamine-hydrolyzing WbpQ. (643 aa) |
| | SO_3264 | SAM-dependent methyltransferase in polysaccharide biosynthesis locus. (395 aa) |
| | SO_3265 | Uncharacterized protein. (412 aa) |
| | SO_3323 | Acteyltransferase GNAT family. (176 aa) |
| | proC | Pyrroline-5-carboxylate reductase ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (272 aa) |
| | glsA | Glutaminase A GlsA; Belongs to the glutaminase family. (304 aa) |
| | thrC | Threonine synthase ThrC. (427 aa) |
| | thrB | Homoserine kinase ThrB; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (312 aa) |
| | thrA | Bifunctional aspartokinase I / homoserine dehydrogenase I ThrA; In the C-terminal section; belongs to the homoserine dehydrogenase family. (822 aa) |
| | SO_3427 | Lysine-sensitive monofunctional aspartokinase LysC family; Belongs to the aspartokinase family. (418 aa) |
| | thiL | Thiamine-phosphate kinase ThiL; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (318 aa) |
| | ribE | Riboflavin synthase beta subunit RibE; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. (158 aa) |
| | ribBA | Bifunctional 34-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (367 aa) |
| | SO_3468 | Riboflavin synthase alpha subunit RibC-like protein. (218 aa) |
| | ribD | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (381 aa) |
| | glyA | Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa) |
| | aptA | Beta-alanine-pyruvate transaminase AptA; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (446 aa) |
| | ribF | Bifunctional flavokinase/FAD synthetase RibF; Belongs to the ribF family. (311 aa) |
| | pgi | Glucose-6-phosphate isomerase Pgi. (545 aa) |
| | cysM | Cysteine synthase B CysM; Belongs to the cysteine synthase/cystathionine beta- synthase family. (292 aa) |
| | pdxA | 4-hydroxy-L-threonine phosphate dehydrogenase PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (328 aa) |
| | folA | Dihydrofolate reductase FolA; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (160 aa) |
| | hmuX | Heme iron utilization protein HmuX. (186 aa) |
| | SO_3705 | 5-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase. (261 aa) |
| | cysI | Sulfite reductase (NADPH) siroheme FeS subunit CysI; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (565 aa) |
| | cysJ | Sulfite reductase (NADPH) flavoprotein subunit CysJ; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (607 aa) |
| | lpxL | Lipid A biosynthesis lauroyl acyltransferase LpxL; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (308 aa) |
| | putA-2 | Bifunctional proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase PutA; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1059 aa) |
| | hprT | Hypoxanthine phosphoribosyltransferase HprT; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (176 aa) |
| | panE | 2-dehydropantoate 2-reductase PanE; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (327 aa) |
| | kdsA | 2-dehydro-3-deoxyphosphooctonate aldolase KdsA; Belongs to the KdsA family. (282 aa) |
| | yjeS | 4Fe-4S binding protein YjeS; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (393 aa) |
| | alr | Alanine racemase biosynthetic Alr; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (358 aa) |
| | hydG | Fe hydrogenase maturation rSAM protein HydG. (479 aa) |
| | hydE | Fe hydrogenase maturation rSAM protein HydE. (359 aa) |
| | lysC | Lysine-sensitive aspartokinase III LysC; Belongs to the aspartokinase family. (451 aa) |
| | fbp | Fructose-16-bisphosphatase Fbp. (325 aa) |
| | metF | 5,10-methylenetetrahydrofolate reductase MetF; Belongs to the methylenetetrahydrofolate reductase family. (297 aa) |
| | metL | Bifunctional aspartokinase II/homoserine dehydrogenase methionine-sensitive MetL; In the C-terminal section; belongs to the homoserine dehydrogenase family. (797 aa) |
| | metJ | Transcriptional repressor of methionine metabolism MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. (104 aa) |
| | SO_4069 | SAM-dependent methyltransferase type 11. (261 aa) |
| | SO_4141 | Oxidoreductase short-chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (243 aa) |
| | ubiE | Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (251 aa) |
| | yigP | Protein of unknown function DUF1243 YigP. (206 aa) |
| | ubiB | 2-polyprenylphenol 6-hydroxylase UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. (549 aa) |
| | leuD | 3-isopropylmalate dehydratase small subunit LeuD; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit LeuC; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (474 aa) |
| | leuB | 3-isopropylmalate dehydrogenase LeuB; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. (364 aa) |
| | leuA | 2-isopropylmalate synthase LeuA; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (522 aa) |
| | argA | Amino-acid acetyltransferase ArgA; Belongs to the acetyltransferase family. ArgA subfamily. (445 aa) |
| | folE | GTP cyclohydrolase I FolE. (216 aa) |
| | pyrE | Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (215 aa) |
| | SO_4305 | HAD-superfamily hydrolase subfamily IA variant 1 family protein. (240 aa) |
| | dapF | Diaminopimelate epimerase DapF; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (275 aa) |
| | lysA | Diaminopimelate decarboxylase LysA; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (414 aa) |
| | hemD | uroporphyrinogen-III synthase HemD; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (246 aa) |
| | SO_4329 | Protein of unknown function DUF526. (84 aa) |
| | ilvD | Dihydroxy-acid dehydratase IlvD; Belongs to the IlvD/Edd family. (619 aa) |
| | ilvM | Acetolactate synthase II small subunit IlvM. (86 aa) |
| | ilvC | Ketol-acid reductoisomerase IlvC; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (492 aa) |
| | SO_4366 | Uncharacterized protein. (246 aa) |
| | SO_4368 | Acyl carrier protein. (84 aa) |
| | acpP-2 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (82 aa) |
| | SO_4372 | Thioester dehydrase family protein. (124 aa) |
| | SO_4375 | acyl-CoA thioester hydrolase, YbgC/YbaW family in fatty acid biosynthesis locus. (144 aa) |
| | SO_4380 | Beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (405 aa) |
| | fabF-2 | 3-oxoacyl-(acyl-carrier-protein) synthase II FabF; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (420 aa) |
| | ysnE | Acteyltransferase GNAT family YsnE. (158 aa) |
| | glnA | Glutamine synthetase GlnA. (469 aa) |
| | SO_4489 | Acteyltransferase GNAT family. (154 aa) |
| | menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase MenD; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). (573 aa) |
| | menH | 2-succinyl-6-hydroxy-24-cyclohexadiene-1- carboxylate synthase MenH; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). (266 aa) |
| | menC | O-succinylbenzoate-CoA synthase MenC; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (374 aa) |
| | bioH | Biotin biosynthesis carboxylesterase BioH; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. (263 aa) |
| | SO_4661 | Membrane protein of unknown function DUF3137. (345 aa) |
| | SO_4680 | CDP-glycerol glycerophosphotransferase family protein. (358 aa) |
| | wcvB | UDP-glucose dehydrogenase WcvB. (387 aa) |
| | SO_4698 | Uncharacterized protein. (176 aa) |
| | SO_4715 | Membrane protein of unknown function DUF165; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (219 aa) |
| | SO_4716 | Acteyltransferase GNAT family. (155 aa) |
| | add | Adenosine deaminase Add; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (331 aa) |
| | menB | Naphthoate synthase MenB; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. (300 aa) |
| | wbnJ | O-antigen biosynthesis acetyltransferase WbnJ. (177 aa) |
| | aroE | Shikimate 5-dehydrogenase AroE; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (287 aa) |
| | mtnC | 2,3-diketo-5-methylthio-1-phosphopentane phosphatase MtnC; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. (226 aa) |
| | ubiC | Chorismate-pyruvate lyase UbiC; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. (189 aa) |
| | ribB | 3,4-dihydroxy-2-butanone 4-phosphate synthase RibB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (217 aa) |
| | SO_0151 | SAM-dependent methyltransferase type 11. (255 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase PckA; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (513 aa) |
| | selD | Selenophosphate synthase SelD; Synthesizes selenophosphate from selenide and ATP. (352 aa) |
| | fabR | Transcriptional repressor of fatty acid biosynthesis FabR. (204 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase ArgC; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (326 aa) |
| | argB | Acetylglutamate kinase ArgB; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (260 aa) |
| | argF | Ornithine carbamoyltransferase ArgF; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (301 aa) |
