STRINGSTRING
parE parE SO_2545 SO_2545 prlS prlS yehU yehU SO_2889 SO_2889 SO_3162 SO_3162 cheA-2 cheA-2 flrB flrB SO_3306 SO_3306 barA barA rstB rstB SO_3688 SO_3688 SO_3894 SO_3894 narQ narQ SO_4002 SO_4002 ttrS ttrS prrB prrB SO_4427 SO_4427 SO_4445 SO_4445 glnL glnL cpxA cpxA SO_4488 SO_4488 SO_4622 SO_4622 envZ envZ SO_4638 SO_4638 SO_4648 SO_4648 SO_4717 SO_4717 gyrB gyrB kdpD kdpD SO_0352 SO_0352 SO_0544 SO_0544 mutL mutL SO_0621 SO_0621 SO_0859 SO_0859 torS torS SO_1417 SO_1417 phoR phoR phoQ phoQ htpG htpG qseC qseC SO_2119 SO_2119 cheA cheA SO_2145 SO_2145 SO_2192 SO_2192 SO_2543 SO_2543 SO_2544 SO_2544
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
parEDNA topoisomerase IV B subunit ParE; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (628 aa)
SO_2545Two component signal transduction system histidine kinase with PAS sensory domain. (429 aa)
prlSProline-responsive two component signal transduction system hybrid histidine kinase/resposne regulator PrlS. (1145 aa)
yehUTwo component signal transduction system histidine kinase with GAF sensory domain YehU. (560 aa)
SO_2889Two component signal transduction system histidine kinase with Cache_1 and PAS sensory domains. (869 aa)
SO_3162Two component signal transduction system histidine kinase with GAF sensory domain. (453 aa)
cheA-2Chemotaxis signal transduction system histidine kinase CheA. (758 aa)
flrBTwo-component system, sensor histidine kinase FlrB; Two component signal transduction system controlling flagellar biosynthesis histidine kinase with PAS sensory domain FlrB. (360 aa)
SO_3306Two component signal transduction system hybrid histidine kinase. (1171 aa)
barAHistidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. (935 aa)
rstBTwo component signal transduction system histidine kinase RstB. (422 aa)
SO_3688Two component signal transduction system histidine kinase. (555 aa)
SO_3894Two component signal transduction system histidine kinase. (543 aa)
narQNitrate/nitrite-responsive two component signal transduction system histidine kinase NarQ. (598 aa)
SO_4002Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. (1702 aa)
ttrSThiosulfate/tetrathionate-responsive two component signal transduction system histidine kinase TtrS. (601 aa)
prrBTwo-component system, sensor histidine kinase RegB; Oxygen-responsive two component signal transduction system controlling redox affected systems histidine kinase PrrB. (427 aa)
SO_4427Two component signal transduction system histidine kinase. (418 aa)
SO_4445Two component signal transduction system hybrid histidine kinase/response regulator. (1141 aa)
glnLNitrogen-responsive two component signal transduction system histidine kinase with PAS sensory domain GlnL. (348 aa)
cpxAPeriplasmic stress-responsive two component signal transduction system histidine kinase CpxA. (449 aa)
SO_4488Two component signal transduction system histidine kinase. (438 aa)
SO_4622Two component signal transduction system histidine kinase. (413 aa)
envZOsmolarity-responsive two component signal transduction system histidine kinase EnvZ. (438 aa)
SO_4638Two component signal transduction system histidine kinase. (430 aa)
SO_4648Two component signal transduction system histidine kinase. (454 aa)
SO_4717Tungstate-responsive two component signal transduction system histidine kinase. (709 aa)
gyrBDNA gyrase B subunit GyrB; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (805 aa)
kdpDTwo component signal transduction system controlling the osmosenstive K+ channel histidine kinase KdpD. (348 aa)
SO_0352Two component signal transduction system histidine kinase. (359 aa)
SO_0544Two component signal transduction system histidine kinase with CHASE and PAS sensory domains. (717 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (631 aa)
SO_0621Two component signal transduction system histidine kinase. (442 aa)
SO_0859Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. (1765 aa)
torSHistidine kinase; TMAO-responsive two component signal transduction system hybrid histidine kinase/response regulator TorS. (1025 aa)
SO_1417Two component signal transduction system histidine kinase. (601 aa)
phoRTwo-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR; Phosphate-responsive two component signal transduction system histidine kinase with PAS and DUF3329 domains PhoR. (432 aa)
phoQTwo component signal transduction system histidine kinase PhoQ. (449 aa)
htpGHeat shock chaperone HtpG; Molecular chaperone. Has ATPase activity. (637 aa)
qseCAI-3-responsive two component signal transduction system histidine kinase QseC. (464 aa)
SO_2119Protein phosphatase with response regulator reciever modulation. (565 aa)
cheAChemotaxis signal transduction system histidine kinase CheA. (702 aa)
SO_2145Two component signal transduction system histidine kinase. (311 aa)
SO_2192Two component signal transduction system controlling sortase system histidine kinase. (719 aa)
SO_2543Two component signal transduction system histidine kinase. (460 aa)
SO_2544Two component signal transduction system hybrid histidine kinase/response regulator with Hpt domain. (1019 aa)
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
Server load: low (26%) [HD]