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birA birA fabZ fabZ ivdG ivdG bioD bioD bioC bioC bioF bioF bioB bioB bioA bioA fabF fabF fabG fabG SO_2813 SO_2813 fabB fabB hydE hydE SO_4380 SO_4380 fabG-2 fabG-2 fabF-2 fabF-2 bioH bioH
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second shell of interactors
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Your Input:
birABifunctional biotin operon repressor/biotin-[acetyl-CoA-carboxylase] ligase BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. (319 aa)
fabZ(3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (154 aa)
ivdG3-hydroxyacyl-CoA dehydrogenase IvdG. (252 aa)
bioDDethiobiotin synthase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (231 aa)
bioCSAM-dependent methylase involved in biotin synthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. (275 aa)
bioF8-amino-7-oxononanoate synthase BioF. (401 aa)
bioBBiotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (350 aa)
bioAAdenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (461 aa)
fabF3-oxoacyl-(acyl-carrier-protein) synthase II FabF; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (412 aa)
fabG3-oxoacyl-(acyl-carrier-protein) reductase FabG; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa)
SO_2813Oxidoreductase short chain dehydrogenase/reductase family. (249 aa)
fabB3-oxoacyl-(acyl-carrier-protein) synthase I FabB; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (411 aa)
hydEFe hydrogenase maturation rSAM protein HydE. (359 aa)
SO_4380Beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (405 aa)
fabG-23-oxoacyl-(acyl-carrier-protein) reductase FabG. (241 aa)
fabF-23-oxoacyl-(acyl-carrier-protein) synthase II FabF; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (420 aa)
bioHBiotin biosynthesis carboxylesterase BioH; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. (263 aa)
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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