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dnaN dnaN holA holA dnaG dnaG rnhB rnhB dnaE dnaE dnaX dnaX SO_2204 SO_2204 SO_2245 SO_2245 dnaQ dnaQ rnhA rnhA holB holB SO_2855 SO_2855 ligA ligA holC holC dnaB dnaB ssb ssb polA polA
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
dnaNDNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] (366 aa)
holADNA polymerase III delta subunit HolA. (343 aa)
dnaGDNA primase DnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (574 aa)
rnhBRibonuclease HII RnhB; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (209 aa)
dnaEDNA polymerase III alpha subunit DnaE. (1158 aa)
dnaXDNA polymerase III gamma and tau subunits DnaX. (1002 aa)
SO_2204DNA ligase ATP-dependent. (311 aa)
SO_2245Exonuclease family protein. (212 aa)
dnaQDNA polymerase III epsilon subunit DnaQ; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (242 aa)
rnhARibonuclease HI RnhA; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (158 aa)
holBDNA polymerase III delta' subunit HolB. (318 aa)
SO_2855Exonuclease. (225 aa)
ligADNA ligase NAD-dependent LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (689 aa)
holCDNA polymerase III chi subunit HolC. (154 aa)
dnaBReplicative DNA helicase DnaB; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (468 aa)
ssbSingle-strand binding protein Ssb; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (238 aa)
polADNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (922 aa)
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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