25 items (Exophiala mesophila) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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Predicted Interactions

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Your Input:
	PV10_06482	HTH TFE/IIEalpha-type domain-containing protein. (487 aa)
	PV10_01121	Uncharacterized protein. (373 aa)
	PV10_05897	CYCLIN domain-containing protein; Belongs to the cyclin family. (403 aa)
	B0A52_02609	S1 domain-containing protein. (169 aa)
	PV10_01985	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1083 aa)
	PV10_03603	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1262 aa)
	PV10_00388	Uncharacterized protein. (78 aa)
	B0A52_01817	RPOL4c domain-containing protein. (152 aa)
	PV10_08543	Uncharacterized protein. (386 aa)
	PV10_06724	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (130 aa)
	PV10_06736	Uncharacterized protein. (846 aa)
	PV10_03751	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (112 aa)
	PV10_04035	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (463 aa)
	PV10_04961	RPOLD domain-containing protein. (337 aa)
	PV10_05091	Uncharacterized protein. (448 aa)
	PV10_02098	RING-type domain-containing protein. (269 aa)
	PV10_02711	DNA repair helicase rad15. (818 aa)
	PV10_03006	RNA_pol_L_2 domain-containing protein. (122 aa)
	PV10_03478	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1761 aa)
	PV10_00436	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (508 aa)
	PV10_01662	Uncharacterized protein. (634 aa)
	PV10_01196	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (705 aa)
	PV10_02041	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (422 aa)
	B0A52_07467	TFIIB-type domain-containing protein. (361 aa)
	PV10_01598	TFIIE beta domain-containing protein. (233 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A52_01817	B0A52_02609	A0A0D1Z4K7	A0A0D1XUD0	RPOL4c domain-containing protein.	S1 domain-containing protein.	0.999
B0A52_01817	B0A52_07467	A0A0D1Z4K7	A0A0D2A8F2	RPOL4c domain-containing protein.	TFIIB-type domain-containing protein.	0.989
B0A52_01817	PV10_00388	A0A0D1Z4K7	A0A0D1Y777	RPOL4c domain-containing protein.	Uncharacterized protein.	0.867
B0A52_01817	PV10_00436	A0A0D1Z4K7	A0A0D1ZPS5	RPOL4c domain-containing protein.	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.971
B0A52_01817	PV10_01121	A0A0D1Z4K7	A0A0D1X6B2	RPOL4c domain-containing protein.	Uncharacterized protein.	0.968
B0A52_01817	PV10_01196	A0A0D1Z4K7	A0A0D1ZU44	RPOL4c domain-containing protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.987
B0A52_01817	PV10_01598	A0A0D1Z4K7	A0A0D2AG49	RPOL4c domain-containing protein.	TFIIE beta domain-containing protein.	0.975
B0A52_01817	PV10_01662	A0A0D1Z4K7	A0A0D1ZTU8	RPOL4c domain-containing protein.	Uncharacterized protein.	0.974
B0A52_01817	PV10_01985	A0A0D1Z4K7	A0A0D1Y107	RPOL4c domain-containing protein.	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.996
B0A52_01817	PV10_02041	A0A0D1Z4K7	A0A0D2A5G3	RPOL4c domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.935
B0A52_01817	PV10_02098	A0A0D1Z4K7	A0A0D1ZK71	RPOL4c domain-containing protein.	RING-type domain-containing protein.	0.983
B0A52_01817	PV10_02711	A0A0D1Z4K7	A0A0D1ZKA8	RPOL4c domain-containing protein.	DNA repair helicase rad15.	0.978
B0A52_01817	PV10_03006	A0A0D1Z4K7	A0A0D1ZL15	RPOL4c domain-containing protein.	RNA_pol_L_2 domain-containing protein.	0.999
B0A52_01817	PV10_03478	A0A0D1Z4K7	A0A0D1ZMK2	RPOL4c domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
B0A52_01817	PV10_03603	A0A0D1Z4K7	A0A0D1Y5W5	RPOL4c domain-containing protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
B0A52_01817	PV10_03751	A0A0D1Z4K7	A0A0D1ZF02	RPOL4c domain-containing protein.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.934
B0A52_01817	PV10_04035	A0A0D1Z4K7	A0A0D1ZFY4	RPOL4c domain-containing protein.	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	0.976
B0A52_01817	PV10_04961	A0A0D1Z4K7	A0A0D1ZGG2	RPOL4c domain-containing protein.	RPOLD domain-containing protein.	0.999
B0A52_01817	PV10_05091	A0A0D1Z4K7	A0A0D1ZGV8	RPOL4c domain-containing protein.	Uncharacterized protein.	0.973
B0A52_01817	PV10_05897	A0A0D1Z4K7	A0A0D1XT79	RPOL4c domain-containing protein.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.928