(8 nodes) HDR through Single Strand Annealing (SSA), and DNA replication factor A complex network (Exophiala mesophila)

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second shell of interactors

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Your Input:
	PV10_08081	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (625 aa)
	B0A52_04315	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (350 aa)
	PV10_06521	Uncharacterized protein. (1608 aa)
	PV10_08755	Uncharacterized protein. (548 aa)
	PV10_04133	Uncharacterized protein. (1099 aa)
	PV10_07844	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (607 aa)
	PV10_04167	Uncharacterized protein. (277 aa)
	PV10_00249	DUF1767 domain-containing protein. (290 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A52_04315	PV10_00249	A0A0D1XLL8	A0A0D2ABR5	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	DUF1767 domain-containing protein.	0.887
B0A52_04315	PV10_04133	A0A0D1XLL8	A0A0D1ZGA6	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	Uncharacterized protein.	0.811
B0A52_04315	PV10_04167	A0A0D1XLL8	A0A0D2A1J8	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	Uncharacterized protein.	0.919
B0A52_04315	PV10_06521	A0A0D1XLL8	A0A0D1XUZ4	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	Uncharacterized protein.	0.992
B0A52_04315	PV10_07844	A0A0D1XLL8	A0A0D1ZUU4	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.991
B0A52_04315	PV10_08081	A0A0D1XLL8	A0A0D1WHV3	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.928
B0A52_04315	PV10_08755	A0A0D1XLL8	A0A0D1Z5J6	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	Uncharacterized protein.	0.994
PV10_00249	B0A52_04315	A0A0D2ABR5	A0A0D1XLL8	DUF1767 domain-containing protein.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.887
PV10_00249	PV10_04133	A0A0D2ABR5	A0A0D1ZGA6	DUF1767 domain-containing protein.	Uncharacterized protein.	0.964
PV10_00249	PV10_04167	A0A0D2ABR5	A0A0D2A1J8	DUF1767 domain-containing protein.	Uncharacterized protein.	0.879
PV10_00249	PV10_06521	A0A0D2ABR5	A0A0D1XUZ4	DUF1767 domain-containing protein.	Uncharacterized protein.	0.991
PV10_00249	PV10_07844	A0A0D2ABR5	A0A0D1ZUU4	DUF1767 domain-containing protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.958
PV10_00249	PV10_08081	A0A0D2ABR5	A0A0D1WHV3	DUF1767 domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.972
PV10_00249	PV10_08755	A0A0D2ABR5	A0A0D1Z5J6	DUF1767 domain-containing protein.	Uncharacterized protein.	0.873
PV10_04133	B0A52_04315	A0A0D1ZGA6	A0A0D1XLL8	Uncharacterized protein.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.811
PV10_04133	PV10_00249	A0A0D1ZGA6	A0A0D2ABR5	Uncharacterized protein.	DUF1767 domain-containing protein.	0.964
PV10_04133	PV10_04167	A0A0D1ZGA6	A0A0D2A1J8	Uncharacterized protein.	Uncharacterized protein.	0.805
PV10_04133	PV10_06521	A0A0D1ZGA6	A0A0D1XUZ4	Uncharacterized protein.	Uncharacterized protein.	0.991
PV10_04133	PV10_07844	A0A0D1ZGA6	A0A0D1ZUU4	Uncharacterized protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.979
PV10_04133	PV10_08081	A0A0D1ZGA6	A0A0D1WHV3	Uncharacterized protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.954