STRINGSTRING
PV10_04196 PV10_04196 PV10_07066 PV10_07066 PV10_04388 PV10_04388 PV10_04545 PV10_04545 MDM12 MDM12 PV10_08310 PV10_08310 PV10_06817 PV10_06817 PV10_04470 PV10_04470 PV10_01113 PV10_01113 MMM1 MMM1 PV10_08792 PV10_08792 MDM34 MDM34 B0A52_05815 B0A52_05815 PV10_05421 PV10_05421 MDM10 MDM10 PIF1 PIF1 PV10_07363 PV10_07363 PV10_01602 PV10_01602 PV10_05904 PV10_05904 PV10_04153 PV10_04153 PV10_04719 PV10_04719 PV10_00527 PV10_00527
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PV10_04196Uncharacterized protein. (605 aa)
PV10_07066Mitochondrial genome maintenance protein mgm101, variant 1. (260 aa)
PV10_04388RRM domain-containing protein. (847 aa)
PV10_04545Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (917 aa)
MDM12Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...] (457 aa)
PV10_08310Uncharacterized protein; Belongs to the ClpA/ClpB family. (788 aa)
PV10_06817Chaperone DnaJ. (566 aa)
PV10_04470POLAc domain-containing protein. (1157 aa)
PV10_01113DNA ligase. (870 aa)
MMM1Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] (503 aa)
PV10_08792Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (388 aa)
MDM34Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (607 aa)
B0A52_05815Mitochondrial import inner membrane translocase subunit tim17. (155 aa)
PV10_05421Ydc2-catalyt domain-containing protein. (336 aa)
MDM10Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...] (513 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (825 aa)
PV10_07363DNA_MISMATCH_REPAIR_2 domain-containing protein. (1006 aa)
PV10_01602Uncharacterized protein. (658 aa)
PV10_05904Uncharacterized protein. (139 aa)
PV10_04153DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1162 aa)
PV10_04719Uncharacterized protein. (752 aa)
PV10_00527Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (403 aa)
Your Current Organism:
Exophiala mesophila
NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.