41 items (Exophiala mesophila) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	PV10_06602	Uncharacterized protein. (255 aa)
	PV10_05706	Uncharacterized protein. (697 aa)
	PV10_07634	Non-specific serine/threonine protein kinase. (871 aa)
	PV10_07630	Chromo domain-containing protein. (241 aa)
	B0A52_01899	CBFD_NFYB_HMF domain-containing protein. (163 aa)
	PV10_02121	R3H domain-containing protein. (1101 aa)
	PV10_04790	Uncharacterized protein. (250 aa)
	PV10_03942	HDAC_interact domain-containing protein. (1518 aa)
	PV10_04026	Uncharacterized protein. (1516 aa)
	PV10_05800	Non-specific serine/threonine protein kinase. (892 aa)
	PV10_06230	Uncharacterized protein. (481 aa)
	PV10_05387	WD_REPEATS_REGION domain-containing protein. (625 aa)
	PV10_05826	WD_REPEATS_REGION domain-containing protein. (335 aa)
	PV10_07826	C2H2-type domain-containing protein. (830 aa)
	PV10_07628	DUF1752 domain-containing protein. (549 aa)
	PV10_07172	Uncharacterized protein. (700 aa)
	PV10_01722	WD_REPEATS_REGION domain-containing protein. (548 aa)
	PV10_03887	Chromo domain-containing protein. (1126 aa)
	PV10_02304	zf-LYAR domain-containing protein. (539 aa)
	PV10_03489	Hist_deacetyl domain-containing protein. (367 aa)
	PV10_00070	Uncharacterized protein. (184 aa)
	PV10_00654	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1427 aa)
	PV10_01028	Uncharacterized protein. (1077 aa)
	PV10_00890	TPR_REGION domain-containing protein. (798 aa)
	PV10_01689	Nitrogen regulatory protein DAL80. (258 aa)
	PV10_03389	CBFD_NFYB_HMF domain-containing protein. (359 aa)
	PV10_08386	Uncharacterized protein. (441 aa)
	PV10_08563	Deacetylase sirtuin-type domain-containing protein. (550 aa)
	PV10_08510	Deacetylase sirtuin-type domain-containing protein. (617 aa)
	PV10_01438	GFO_IDH_MocA domain-containing protein. (368 aa)
	PV10_00663	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (706 aa)
	PV10_00274	Plus3 domain-containing protein. (606 aa)
	PV10_03314	FAS1 domain-containing protein. (236 aa)
	PV10_03145	Thioredoxin-like_fold domain-containing protein. (210 aa)
	PV10_03134	Uncharacterized protein. (475 aa)
	PV10_04896	Uncharacterized protein. (874 aa)
	PV10_06162	UV excision repair protein Rad23. (398 aa)
	PV10_08324	SANT_DAMP1_like domain-containing protein. (858 aa)
	PV10_08216	Rtt106 domain-containing protein. (522 aa)
	PV10_01820	Uncharacterized protein. (725 aa)
	PV10_01600	Deacetylase sirtuin-type domain-containing protein. (625 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A52_01899	PV10_03389	A0A0D1XQK4	A0A0D1ZP68	CBFD_NFYB_HMF domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.990
B0A52_01899	PV10_05387	A0A0D1XQK4	A0A0D1Z9T5	CBFD_NFYB_HMF domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.780
PV10_00274	PV10_00654	A0A0D1Y6N2	A0A0D1ZQE5	Plus3 domain-containing protein.	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	0.958
PV10_00274	PV10_00663	A0A0D1Y6N2	A0A0D1Y7V8	Plus3 domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.720
PV10_00274	PV10_00890	A0A0D1Y6N2	A0A0D1ZT70	Plus3 domain-containing protein.	TPR_REGION domain-containing protein.	0.574
PV10_00654	PV10_00274	A0A0D1ZQE5	A0A0D1Y6N2	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	Plus3 domain-containing protein.	0.958
PV10_00654	PV10_00663	A0A0D1ZQE5	A0A0D1Y7V8	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.725
PV10_00654	PV10_00890	A0A0D1ZQE5	A0A0D1ZT70	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	TPR_REGION domain-containing protein.	0.409
PV10_00654	PV10_05387	A0A0D1ZQE5	A0A0D1Z9T5	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	WD_REPEATS_REGION domain-containing protein.	0.469
PV10_00654	PV10_08324	A0A0D1ZQE5	A0A0D1XKD1	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	SANT_DAMP1_like domain-containing protein.	0.499
PV10_00663	PV10_00274	A0A0D1Y7V8	A0A0D1Y6N2	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Plus3 domain-containing protein.	0.720
PV10_00663	PV10_00654	A0A0D1Y7V8	A0A0D1ZQE5	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	0.725
PV10_00663	PV10_00890	A0A0D1Y7V8	A0A0D1ZT70	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	TPR_REGION domain-containing protein.	0.564
PV10_00663	PV10_06162	A0A0D1Y7V8	A0A0D1XTY3	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	UV excision repair protein Rad23.	0.594
PV10_00663	PV10_06230	A0A0D1Y7V8	A0A0D1ZAJ1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.480
PV10_00890	PV10_00274	A0A0D1ZT70	A0A0D1Y6N2	TPR_REGION domain-containing protein.	Plus3 domain-containing protein.	0.574
PV10_00890	PV10_00654	A0A0D1ZT70	A0A0D1ZQE5	TPR_REGION domain-containing protein.	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	0.409
PV10_00890	PV10_00663	A0A0D1ZT70	A0A0D1Y7V8	TPR_REGION domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.564
PV10_00890	PV10_01722	A0A0D1ZT70	A0A0D1ZVN3	TPR_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.555
PV10_00890	PV10_05387	A0A0D1ZT70	A0A0D1Z9T5	TPR_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.990