STRINGSTRING
PV10_06149 PV10_06149 PV10_07947 PV10_07947 PV10_08211 PV10_08211 PV10_08668 PV10_08668 PV10_07313 PV10_07313 PV10_05603 PV10_05603 PV10_02096 PV10_02096 MCM7 MCM7 PV10_02301 PV10_02301 PV10_03009 PV10_03009 PV10_03092 PV10_03092 PV10_03455 PV10_03455 SLX4 SLX4 PV10_03496 PV10_03496 PV10_00523 PV10_00523 PV10_01221 PV10_01221 PV10_01307 PV10_01307 PV10_01595 PV10_01595 PV10_08324 PV10_08324 PV10_08625 PV10_08625 B0A52_04315 B0A52_04315 PV10_08739 PV10_08739 PV10_06885 PV10_06885 PV10_07012 PV10_07012 PV10_07087 PV10_07087 PV10_07517 PV10_07517 PV10_07753 PV10_07753 PV10_05490 PV10_05490 PV10_06115 PV10_06115 PV10_04096 PV10_04096 PV10_04192 PV10_04192 PV10_04235 PV10_04235 PV10_04251 PV10_04251 PV10_04957 PV10_04957 PV10_02436 PV10_02436 PV10_03089 PV10_03089 PV10_03497 PV10_03497 B0A52_06663 B0A52_06663 PV10_00667 PV10_00667 PV10_00690 PV10_00690 PV10_01681 PV10_01681 PV10_01821 PV10_01821 PV10_08035 PV10_08035 PV10_08147 PV10_08147 PV10_07047 PV10_07047 B0A52_03640 B0A52_03640 PV10_08948 PV10_08948 PV10_07039 PV10_07039 PV10_07563 PV10_07563 PV10_05940 PV10_05940 PV10_06230 PV10_06230 PV10_05574 PV10_05574 PV10_06358 PV10_06358 PV10_06387 PV10_06387 SLX1 SLX1 PV10_06251 PV10_06251 PV10_06514 PV10_06514 PV10_03991 PV10_03991 PV10_04813 PV10_04813 PV10_04857 PV10_04857 PV10_04953 PV10_04953 PV10_04996 PV10_04996 PV10_02798 PV10_02798 PV10_02922 PV10_02922 PV10_03624 PV10_03624 PV10_03095 PV10_03095 PV10_03156 PV10_03156 PV10_08151 PV10_08151 PV10_07084 PV10_07084 PV10_01305 PV10_01305 PV10_01710 PV10_01710 PV10_01743 PV10_01743 PV10_01793 PV10_01793 PV10_07844 PV10_07844 PV10_01469 PV10_01469 PV10_01777 PV10_01777 PV10_01881 PV10_01881 PV10_05932 PV10_05932 PV10_06044 PV10_06044 PV10_06691 PV10_06691 PV10_03975 PV10_03975 PV10_04167 PV10_04167 B0A52_04834 B0A52_04834 PV10_04499 PV10_04499 PV10_02294 PV10_02294 PV10_02331 PV10_02331 PV10_02657 PV10_02657 PV10_03424 PV10_03424 PV10_00432 PV10_00432 PV10_01287 PV10_01287 PV10_01372 PV10_01372
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PV10_06149PHD domain-containing protein. (564 aa)
PV10_07947RXT2_N domain-containing protein. (478 aa)
PV10_08211Sld5 domain-containing protein. (236 aa)
PV10_08668WD_REPEATS_REGION domain-containing protein. (316 aa)
PV10_07313SET domain-containing protein. (944 aa)
PV10_05603Checkpoint protein; Belongs to the HUS1 family. (351 aa)
PV10_02096Uncharacterized protein. (1391 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (808 aa)
PV10_02301Uncharacterized protein. (801 aa)
PV10_03009Zn(2)-C6 fungal-type domain-containing protein. (725 aa)
PV10_03092Uncharacterized protein. (744 aa)
PV10_03455AAA_23 domain-containing protein. (1306 aa)
SLX4Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (919 aa)
PV10_03496Uncharacterized protein. (1510 aa)
PV10_00523DNA primase; Belongs to the eukaryotic-type primase small subunit family. (530 aa)
PV10_01221Uncharacterized protein. (714 aa)
PV10_01307Vezatin domain-containing protein. (585 aa)
PV10_01595Sld5 domain-containing protein. (182 aa)
PV10_08324SANT_DAMP1_like domain-containing protein. (858 aa)
PV10_08625ING domain-containing protein. (827 aa)
B0A52_04315DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (350 aa)
PV10_08739Uncharacterized protein. (1665 aa)
PV10_06885Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family. (723 aa)
PV10_07012DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (452 aa)
PV10_07087DNA polymerase. (1453 aa)
PV10_07517Uncharacterized protein; Belongs to the actin family. (476 aa)
PV10_07753DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (507 aa)
PV10_05490UmuC domain-containing protein. (652 aa)
PV10_06115Uncharacterized protein. (1674 aa)
PV10_04096Uncharacterized protein. (583 aa)
PV10_04192NET domain-containing protein. (247 aa)
PV10_04235Uncharacterized protein. (609 aa)
PV10_04251DNA helicase; Belongs to the MCM family. (724 aa)
PV10_04957Uncharacterized protein; Belongs to the actin family. (765 aa)
PV10_02436WD_REPEATS_REGION domain-containing protein. (726 aa)
PV10_03089YL1_C domain-containing protein. (723 aa)
PV10_03497Piwi domain-containing protein. (1065 aa)
B0A52_06663Uncharacterized protein. (77 aa)
PV10_00667MRC1 domain-containing protein. (1394 aa)
PV10_00690Uncharacterized protein. (862 aa)
PV10_01681DNA helicase; Belongs to the MCM family. (863 aa)
PV10_01821RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (457 aa)
PV10_08035Ubiquitin-like domain-containing protein. (101 aa)
PV10_08147Uncharacterized protein. (2029 aa)
PV10_07047DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (245 aa)
B0A52_03640Uncharacterized protein. (259 aa)
PV10_08948Uncharacterized protein. (1891 aa)
PV10_07039NDT80 domain-containing protein. (512 aa)
PV10_07563ORC_WH_C domain-containing protein. (761 aa)
PV10_05940Uncharacterized protein. (611 aa)
PV10_06230Uncharacterized protein. (481 aa)
PV10_05574Uncharacterized protein; Belongs to the argonaute family. (1000 aa)
PV10_06358FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (568 aa)
PV10_06387DNA_pol_E_B domain-containing protein. (856 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (399 aa)
PV10_06251Uncharacterized protein. (436 aa)
PV10_06514DNA helicase; Belongs to the MCM family. (1004 aa)
PV10_03991RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (485 aa)
PV10_04813DNA polymerase. (1107 aa)
PV10_04857Hist_deacetyl domain-containing protein. (716 aa)
PV10_04953YL1_C domain-containing protein. (209 aa)
PV10_04996RING-type domain-containing protein. (449 aa)
PV10_02798Structural maintenance of chromosomes protein. (1205 aa)
PV10_02922Zf-primase domain-containing protein. (781 aa)
PV10_03624Uncharacterized protein. (363 aa)
PV10_03095PHD-type domain-containing protein. (1119 aa)
PV10_03156H15 domain-containing protein. (233 aa)
PV10_08151Uncharacterized protein. (1420 aa)
PV10_07084DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2242 aa)
PV10_01305Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (267 aa)
PV10_01710NDT80 domain-containing protein. (622 aa)
PV10_01743PAPA-1 domain-containing protein. (490 aa)
PV10_01793MRG domain-containing protein. (410 aa)
PV10_07844Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (607 aa)
PV10_01469DNA helicase; Belongs to the MCM family. (915 aa)
PV10_01777Chromatin modification-related protein. (776 aa)
PV10_01881Uncharacterized protein. (906 aa)
PV10_05932DNA helicase; Belongs to the MCM family. (963 aa)
PV10_06044Uncharacterized protein. (560 aa)
PV10_06691TP6A_N domain-containing protein. (370 aa)
PV10_03975WD_REPEATS_REGION domain-containing protein. (864 aa)
PV10_04167Uncharacterized protein. (277 aa)
B0A52_04834Histone H2A; Belongs to the histone H2A family. (139 aa)
PV10_04499DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (654 aa)
PV10_02294Uncharacterized protein. (504 aa)
PV10_02331Uncharacterized protein. (228 aa)
PV10_02657Uncharacterized protein. (791 aa)
PV10_03424Uncharacterized protein. (281 aa)
PV10_00432Uncharacterized protein; Belongs to the actin family. (474 aa)
PV10_01287HORMA domain-containing protein. (207 aa)
PV10_01372CBFD_NFYB_HMF domain-containing protein. (349 aa)
Your Current Organism:
Exophiala mesophila
NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila
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