(11 nodes) Double-strand break repair via break-induced replication network (Exophiala mesophila)

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second shell of interactors

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Your Input:
	PV10_06514	DNA helicase; Belongs to the MCM family. (1004 aa)
	PV10_02657	Uncharacterized protein. (791 aa)
	PV10_05932	DNA helicase; Belongs to the MCM family. (963 aa)
	PV10_01469	DNA helicase; Belongs to the MCM family. (915 aa)
	PV10_00814	ERCC4 domain-containing protein. (612 aa)
	PV10_00324	Protein kinase domain-containing protein. (573 aa)
	PV10_01681	DNA helicase; Belongs to the MCM family. (863 aa)
	PV10_04251	DNA helicase; Belongs to the MCM family. (724 aa)
	PV10_01595	Sld5 domain-containing protein. (182 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (808 aa)
	PV10_08211	Sld5 domain-containing protein. (236 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCM7	PV10_00324	A0A0D1WY54	A0A0D1ZR79	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Protein kinase domain-containing protein.	0.991
MCM7	PV10_01469	A0A0D1WY54	A0A0D1ZUV0	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PV10_01595	A0A0D1WY54	A0A0D1X7Q3	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Sld5 domain-containing protein.	0.995
MCM7	PV10_01681	A0A0D1WY54	A0A0D1YBK4	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PV10_02657	A0A0D1WY54	A0A0D2A7I5	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Uncharacterized protein.	0.998
MCM7	PV10_04251	A0A0D1WY54	A0A0D1XXT6	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PV10_05932	A0A0D1WY54	A0A0D1ZX42	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PV10_06514	A0A0D1WY54	A0A0D1ZDQ5	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PV10_08211	A0A0D1WY54	A0A0D1WIB0	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Sld5 domain-containing protein.	0.993
PV10_00324	MCM7	A0A0D1ZR79	A0A0D1WY54	Protein kinase domain-containing protein.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.991
PV10_00324	PV10_01469	A0A0D1ZR79	A0A0D1ZUV0	Protein kinase domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.993
PV10_00324	PV10_01595	A0A0D1ZR79	A0A0D1X7Q3	Protein kinase domain-containing protein.	Sld5 domain-containing protein.	0.530
PV10_00324	PV10_01681	A0A0D1ZR79	A0A0D1YBK4	Protein kinase domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.997
PV10_00324	PV10_02657	A0A0D1ZR79	A0A0D2A7I5	Protein kinase domain-containing protein.	Uncharacterized protein.	0.907
PV10_00324	PV10_04251	A0A0D1ZR79	A0A0D1XXT6	Protein kinase domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.994
PV10_00324	PV10_05932	A0A0D1ZR79	A0A0D1ZX42	Protein kinase domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.992
PV10_00324	PV10_06514	A0A0D1ZR79	A0A0D1ZDQ5	Protein kinase domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.996
PV10_00814	PV10_02657	A0A0D1ZT10	A0A0D2A7I5	ERCC4 domain-containing protein.	Uncharacterized protein.	0.477
PV10_00814	PV10_05932	A0A0D1ZT10	A0A0D1ZX42	ERCC4 domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.411
PV10_01469	MCM7	A0A0D1ZUV0	A0A0D1WY54	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999