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PV10_08526 PV10_08526 PV10_08738 PV10_08738 PV10_06898 PV10_06898 PV10_06955 PV10_06955 B0A52_06827 B0A52_06827 PV10_05356 PV10_05356 PV10_05731 PV10_05731 PV10_05896 PV10_05896 B0A52_05137 B0A52_05137 PV10_06411 PV10_06411 PV10_06441 PV10_06441 PV10_06717 PV10_06717 PV10_01563 PV10_01563 PV10_03923 PV10_03923 PV10_04051 PV10_04051 PV10_04234 PV10_04234 PV10_04383 PV10_04383 PV10_04491 PV10_04491 PV10_04711 PV10_04711 PV10_04895 PV10_04895 PV10_02271 PV10_02271 PV10_02429 PV10_02429 PV10_02453 PV10_02453 PV10_02507 PV10_02507 PV10_02851 PV10_02851 PV10_03026 PV10_03026 PV10_03152 PV10_03152 PV10_03515 PV10_03515 PV10_00130 PV10_00130 PV10_00315 PV10_00315 PV10_00418 PV10_00418 PV10_01077 PV10_01077 PV10_01226 PV10_01226 PV10_01572 PV10_01572 PV10_01769 PV10_01769 PV10_01782 PV10_01782 PV10_07976 PV10_07976 PV10_08037 PV10_08037 PV10_08178 PV10_08178 DRE2 DRE2 PV10_08459 PV10_08459 PV10_08635 PV10_08635 PV10_06951 PV10_06951 PV10_07154 PV10_07154 PV10_07288 PV10_07288 PV10_07467 PV10_07467 PV10_07700 PV10_07700 PV10_01571 PV10_01571 PV10_01589 PV10_01589 PV10_01708 PV10_01708 PV10_01849 PV10_01849 PV10_01876 PV10_01876 PV10_05780 PV10_05780 PV10_06810 PV10_06810 PV10_04232 PV10_04232 PV10_04268 PV10_04268 PV10_04308 PV10_04308 PV10_04743 PV10_04743 PV10_02619 PV10_02619 PV10_02961 PV10_02961 PV10_00056 PV10_00056 PV10_00300 PV10_00300 PV10_00328 PV10_00328 PV10_00450 PV10_00450 PV10_00481 PV10_00481 PV10_01204 PV10_01204 PV10_01491 PV10_01491 PV10_01538 PV10_01538 PV10_01603 PV10_01603 PV10_01635 PV10_01635 PV10_01724 PV10_01724 PV10_01882 PV10_01882 PV10_09056 PV10_09056 PV10_08045 PV10_08045 PV10_08276 PV10_08276 PV10_07142 PV10_07142 PV10_07500 PV10_07500 PV10_08852 PV10_08852 PV10_07701 PV10_07701 B0A52_09313 B0A52_09313 PV10_07721 PV10_07721 PV10_07873 PV10_07873 PV10_07186 PV10_07186 PV10_07205 PV10_07205 PV10_07590 PV10_07590 PV10_05842 PV10_05842 PV10_05654 PV10_05654 PV10_05786 PV10_05786 PV10_06739 PV10_06739 PV10_03749 PV10_03749 PV10_06280 PV10_06280 PV10_03828 PV10_03828 PV10_04136 PV10_04136 PV10_06625 PV10_06625 PV10_06648 PV10_06648 PV10_01350 PV10_01350 COQ5 COQ5 PV10_04213 PV10_04213 PV10_06696 PV10_06696 PV10_04240 PV10_04240 PV10_04366 PV10_04366 PV10_04442 PV10_04442 B0A52_09673 B0A52_09673 PV10_03971 PV10_03971 PV10_04975 PV10_04975 cprA cprA PV10_04468 PV10_04468 PV10_02014 PV10_02014 PV10_04695 PV10_04695 PV10_02175 PV10_02175 PV10_05084 PV10_05084 PV10_01983 PV10_01983 PV10_02327 PV10_02327 PV10_05337 PV10_05337 PV10_05357 PV10_05357 PV10_05717 PV10_05717 PV10_06084 PV10_06084 PV10_03963 PV10_03963 PV10_04042 PV10_04042 B0A52_04890 B0A52_04890 PV10_04399 PV10_04399 PV10_02264 PV10_02264 PV10_02445 PV10_02445 PV10_02498 PV10_02498 PV10_02553 PV10_02553 PV10_02793 PV10_02793 PV10_03045 PV10_03045 PV10_00193 PV10_00193 PV10_00336 PV10_00336 PV10_00627 PV10_00627 PV10_00919 PV10_00919 PV10_01275 PV10_01275 B0A52_07543 B0A52_07543 PV10_03219 PV10_03219 PV10_03171 PV10_03171 PV10_03244 PV10_03244 PV10_08248 PV10_08248 PV10_00337 PV10_00337 PV10_00384 PV10_00384 PV10_00420 PV10_00420 PV10_08559 PV10_08559 PV10_00659 PV10_00659 PV10_00230 PV10_00230 PV10_01023 PV10_01023 PV10_06848 PV10_06848 PV10_07089 PV10_07089 PV10_00722 PV10_00722 PV10_07285 PV10_07285 PV10_00879 PV10_00879 PV10_07411 PV10_07411 PV10_07430 PV10_07430 PV10_07567 PV10_07567 PV10_01771 PV10_01771 PV10_07687 PV10_07687 PV10_07921 PV10_07921 PV10_08990 PV10_08990
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PV10_08526Uncharacterized protein. (79 aa)
PV10_08738Uncharacterized protein. (160 aa)
PV10_06898Triosephosphate isomerase. (306 aa)
PV10_06955Uncharacterized protein. (483 aa)
B0A52_06827Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (295 aa)
PV10_05356Fumarate hydratase, class II. (542 aa)
PV10_05731PKS_ER domain-containing protein. (376 aa)
PV10_05896Uncharacterized protein. (360 aa)
B0A52_05137Electron transfer flavoprotein subunit beta. (255 aa)
PV10_06411Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (704 aa)
PV10_06441Uncharacterized protein. (69 aa)
PV10_06717PKS_ER domain-containing protein. (379 aa)
PV10_01563UCR_hinge domain-containing protein. (133 aa)
PV10_03923Uncharacterized protein. (161 aa)
PV10_04051Uncharacterized protein. (467 aa)
PV10_04234Tafazzin family protein; Belongs to the taffazin family. (458 aa)
PV10_04383NADH-ubiquinone oxidoreductase 78 kDa subunit, mitochondrial; Belongs to the complex I 75 kDa subunit family. (741 aa)
PV10_04491Uncharacterized protein. (463 aa)
PV10_04711Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (244 aa)
PV10_04895Glyceraldehyde-3-phosphate dehydrogenase. (337 aa)
PV10_02271Pyruvate kinase; Belongs to the pyruvate kinase family. (525 aa)
PV10_02429ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (791 aa)
PV10_02453PKS_ER domain-containing protein. (452 aa)
PV10_02507Pyrid_ox_like domain-containing protein. (197 aa)
PV10_02851Uncharacterized protein. (393 aa)
PV10_03026PKS_ER domain-containing protein. (360 aa)
PV10_03152Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (648 aa)
PV10_03515UTP--glucose-1-phosphate uridylyltransferase. (525 aa)
PV10_00130Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (784 aa)
PV10_00315Isocitrate lyase. (537 aa)
PV10_00418Uncharacterized protein. (581 aa)
PV10_01077Uncharacterized protein. (192 aa)
PV10_01226Uncharacterized protein. (113 aa)
PV10_01572Uncharacterized protein. (570 aa)
PV10_01769Cytochrome c oxidase subunit 6A, mitochondrial. (143 aa)
PV10_01782Malate dehydrogenase. (340 aa)
PV10_07976Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (577 aa)
PV10_08037CoA_binding domain-containing protein. (704 aa)
PV10_08178NADH-ubiquinone oxidoreductase 19.3 kDa subunit, mitochondrial; Belongs to the complex I 20 kDa subunit family. (232 aa)
DRE2Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (349 aa)
PV10_08459Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (815 aa)
PV10_08635Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (418 aa)
PV10_06951Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (480 aa)
PV10_07154Uncharacterized protein. (345 aa)
PV10_07288Glucose-6-phosphate isomerase; Belongs to the GPI family. (552 aa)
PV10_07467Uncharacterized protein. (188 aa)
PV10_07700Uncharacterized protein. (239 aa)
PV10_01571Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (111 aa)
PV10_01589Uncharacterized protein. (142 aa)
PV10_01708Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (257 aa)
PV10_01849Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (895 aa)
PV10_01876Uncharacterized protein. (3242 aa)
PV10_05780PKS_ER domain-containing protein. (406 aa)
PV10_06810Succinate dehydrogenase, cytochrome b556 subunit. (223 aa)
PV10_04232Phosphotransferase. (489 aa)
PV10_04268zf-CHCC domain-containing protein. (243 aa)
PV10_04308Fumarate hydratase, class II. (468 aa)
PV10_04743Pyr_redox_2 domain-containing protein. (586 aa)
PV10_02619NAD(P)(+) transhydrogenase (AB-specific), alpha subunit. (1102 aa)
PV10_02961Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (360 aa)
PV10_000562,3-bisphosphoglycerate-independent phosphoglycerate mutase. (532 aa)
PV10_00300NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial. (228 aa)
PV10_00328Pyr_redox_2 domain-containing protein. (366 aa)
PV10_00450Uncharacterized protein. (344 aa)
PV10_00481Succinate dehydrogenase [ubiquinone] cytochrome b small subunit. (219 aa)
PV10_01204Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (427 aa)
PV10_01491Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. (1049 aa)
PV10_01538Pyruvate carboxyltransferase domain-containing protein. (367 aa)
PV10_01603Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (383 aa)
PV10_01635Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (502 aa)
PV10_01724Uncharacterized protein. (314 aa)
PV10_01882NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (508 aa)
PV10_09056Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (330 aa)
PV10_08045PKS_ER domain-containing protein. (317 aa)
PV10_08276Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (123 aa)
PV10_07142Uncharacterized protein; Belongs to the complex I LYR family. (81 aa)
PV10_075006-phosphogluconate dehydrogenase, decarboxylating; Belongs to the 6-phosphogluconate dehydrogenase family. (528 aa)
PV10_08852Uncharacterized protein. (548 aa)
PV10_07701Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (445 aa)
B0A52_09313Uncharacterized protein. (103 aa)
PV10_07721Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (548 aa)
PV10_07873Uncharacterized protein. (271 aa)
PV10_07186Uncharacterized protein. (397 aa)
PV10_07205Phosphotransferase. (524 aa)
PV10_07590NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial; Belongs to the complex I 49 kDa subunit family. (480 aa)
PV10_05842Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (324 aa)
PV10_05654Malate dehydrogenase. (341 aa)
PV10_05786Uncharacterized protein. (767 aa)
PV10_06739PKS_ER domain-containing protein. (358 aa)
PV10_03749Phosphotransferase. (586 aa)
PV10_06280ATP synthase F1, delta subunit. (224 aa)
PV10_03828Pyr_redox_2 domain-containing protein. (415 aa)
PV10_04136Uncharacterized protein. (458 aa)
PV10_06625NADH-ubiquinone oxidoreductase 30.4 kDa subunit, mitochondrial; Belongs to the complex I 30 kDa subunit family. (301 aa)
PV10_06648Zn(2)-C6 fungal-type domain-containing protein. (712 aa)
PV10_01350Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (631 aa)
COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (305 aa)
PV10_04213Pyr_redox_2 domain-containing protein. (437 aa)
PV10_06696NADH-ubiquinone oxidoreductase; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (158 aa)
PV10_04240Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. (311 aa)
PV10_043662Fe-2S ferredoxin-type domain-containing protein. (213 aa)
PV10_04442Uncharacterized protein. (227 aa)
B0A52_09673Uncharacterized protein. (76 aa)
PV10_039711,4-alpha-glucan-branching enzyme. (699 aa)
PV10_04975Ribose 5-phosphate isomerase A. (296 aa)
cprANADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (691 aa)
PV10_04468Uncharacterized protein. (375 aa)
PV10_02014Uncharacterized protein. (335 aa)
PV10_04695Fungal_trans domain-containing protein. (1196 aa)
PV10_02175Citrate synthase; Belongs to the citrate synthase family. (467 aa)
PV10_05084Triosephosphate isomerase. (249 aa)
PV10_01983Polyketide_cyc domain-containing protein. (202 aa)
PV10_02327Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (387 aa)
PV10_05337Malate synthase; Belongs to the malate synthase family. (542 aa)
PV10_05357Pyr_redox_2 domain-containing protein. (383 aa)
PV10_05717Pyr_redox_2 domain-containing protein. (399 aa)
PV10_06084Phosphotransferase. (496 aa)
PV10_03963Uncharacterized protein. (208 aa)
PV10_04042Uncharacterized protein. (584 aa)
B0A52_04890Citrate synthase; Belongs to the citrate synthase family. (471 aa)
PV10_04399Fe-ADH domain-containing protein. (493 aa)
PV10_02264Glycogen debranching enzyme. (1552 aa)
PV10_02445Enolase. (438 aa)
PV10_02498Uncharacterized protein. (456 aa)
PV10_02553Tartrate dehydrogenase. (364 aa)
PV10_02793Pyr_redox_2 domain-containing protein. (446 aa)
PV10_03045Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (291 aa)
PV10_00193Uncharacterized protein. (103 aa)
PV10_00336Uncharacterized protein; Belongs to the complex I LYR family. (106 aa)
PV10_00627ADH_zinc_N domain-containing protein. (270 aa)
PV10_00919ETF domain-containing protein. (349 aa)
PV10_01275Uncharacterized protein. (435 aa)
B0A52_07543Cytochrome c1, heme protein, mitochondrial. (321 aa)
PV10_03219Uncharacterized protein. (1102 aa)
PV10_03171Uncharacterized protein. (205 aa)
PV10_032446-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (265 aa)
PV10_08248Phosphopyruvate hydratase. (446 aa)
PV10_00337Lipoyl-binding domain-containing protein. (463 aa)
PV10_00384Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (463 aa)
PV10_00420Uncharacterized protein. (575 aa)
PV10_08559Uncharacterized protein. (187 aa)
PV10_00659Haloacid dehalogenase, type II. (234 aa)
PV10_00230Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (524 aa)
PV10_01023Uncharacterized protein. (598 aa)
PV10_06848Uncharacterized protein. (239 aa)
PV10_07089Hydrolase_4 domain-containing protein. (323 aa)
PV10_00722Fumarate hydratase, class II. (513 aa)
PV10_07285Fungal_trans domain-containing protein. (600 aa)
PV10_00879S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (381 aa)
PV10_07411Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (510 aa)
PV10_07430PKS_ER domain-containing protein. (374 aa)
PV10_07567Uncharacterized protein. (188 aa)
PV10_01771CIA30 domain-containing protein. (306 aa)
PV10_07687Pyruvate carboxyltransferase domain-containing protein. (624 aa)
PV10_07921Alternative oxidase. (342 aa)
PV10_08990Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (504 aa)
Your Current Organism:
Exophiala mesophila
NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila
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