36 items (Exophiala mesophila) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	PV10_02098	RING-type domain-containing protein. (269 aa)
	B0A52_01655	26S protease regulatory subunit 8 A; Belongs to the AAA ATPase family. (389 aa)
	PV10_07274	Uncharacterized protein. (1195 aa)
	PV10_05603	Checkpoint protein; Belongs to the HUS1 family. (351 aa)
	B0A52_02785	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (393 aa)
	PV10_02985	Uncharacterized protein. (642 aa)
	PV10_03105	DNA ligase. (855 aa)
	PV10_06162	UV excision repair protein Rad23. (398 aa)
	PV10_06413	DNA repair protein. (364 aa)
	PV10_04578	CULLIN_2 domain-containing protein; Belongs to the cullin family. (896 aa)
	PV10_02203	WD_REPEATS_REGION domain-containing protein. (521 aa)
	PV10_02986	Uncharacterized protein. (988 aa)
	PV10_03580	Uncharacterized protein. (1124 aa)
	PV10_00274	Plus3 domain-containing protein. (606 aa)
	PV10_00388	Uncharacterized protein. (78 aa)
	NTH1	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (437 aa)
	PV10_06957	Uncharacterized protein. (1110 aa)
	PV10_08487	Uncharacterized protein. (377 aa)
	PV10_05473	ERCC4 domain-containing protein. (948 aa)
	PV10_07520	ENDO3c domain-containing protein. (419 aa)
	PV10_06724	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (130 aa)
	PV10_06426	Uncharacterized protein. (1041 aa)
	PV10_06736	Uncharacterized protein. (846 aa)
	PV10_04035	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (463 aa)
	PV10_04813	DNA polymerase. (1107 aa)
	PV10_05091	Uncharacterized protein. (448 aa)
	PV10_02437	Uncharacterized protein. (1343 aa)
	PV10_02711	DNA repair helicase rad15. (818 aa)
	PV10_00436	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (508 aa)
	PV10_00812	CUE domain-containing protein. (879 aa)
	PV10_07084	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2242 aa)
	PV10_01662	Uncharacterized protein. (634 aa)
	PV10_07844	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (607 aa)
	PV10_04167	Uncharacterized protein. (277 aa)
	PV10_04883	RRM domain-containing protein. (252 aa)
	PV10_04918	Uncharacterized protein. (1151 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A52_01655	B0A52_02785	A0A0D1WLN0	A0A0D1WYY1	26S protease regulatory subunit 8 A; Belongs to the AAA ATPase family.	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	0.999
B0A52_01655	PV10_02711	A0A0D1WLN0	A0A0D1ZKA8	26S protease regulatory subunit 8 A; Belongs to the AAA ATPase family.	DNA repair helicase rad15.	0.546
B0A52_01655	PV10_02985	A0A0D1WLN0	A0A0D1X0L4	26S protease regulatory subunit 8 A; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.405
B0A52_01655	PV10_06162	A0A0D1WLN0	A0A0D1XTY3	26S protease regulatory subunit 8 A; Belongs to the AAA ATPase family.	UV excision repair protein Rad23.	0.967
B0A52_02785	B0A52_01655	A0A0D1WYY1	A0A0D1WLN0	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	26S protease regulatory subunit 8 A; Belongs to the AAA ATPase family.	0.999
B0A52_02785	PV10_02985	A0A0D1WYY1	A0A0D1X0L4	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.439
B0A52_02785	PV10_06162	A0A0D1WYY1	A0A0D1XTY3	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	UV excision repair protein Rad23.	0.901
NTH1	PV10_02437	A0A0D1Y905	A0A0D1ZJ95	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	Uncharacterized protein.	0.662
NTH1	PV10_02711	A0A0D1Y905	A0A0D1ZKA8	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	DNA repair helicase rad15.	0.471
NTH1	PV10_03580	A0A0D1Y905	A0A0D1Y5S0	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	Uncharacterized protein.	0.431
NTH1	PV10_04813	A0A0D1Y905	A0A0D1ZG00	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	DNA polymerase.	0.582
NTH1	PV10_05473	A0A0D1Y905	A0A0D1Z7W0	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	ERCC4 domain-containing protein.	0.635
NTH1	PV10_06162	A0A0D1Y905	A0A0D1XTY3	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	UV excision repair protein Rad23.	0.433
NTH1	PV10_06413	A0A0D1Y905	A0A0D1XUN9	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	DNA repair protein.	0.597
NTH1	PV10_06736	A0A0D1Y905	A0A0D1ZE99	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	Uncharacterized protein.	0.448
NTH1	PV10_07084	A0A0D1Y905	A0A0D1ZSC2	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.549
NTH1	PV10_07274	A0A0D1Y905	A0A0D1WLP0	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	Uncharacterized protein.	0.433
NTH1	PV10_07520	A0A0D1Y905	A0A0D1Z841	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	ENDO3c domain-containing protein.	0.660
NTH1	PV10_08487	A0A0D1Y905	A0A0D1Z4J4	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	Uncharacterized protein.	0.507
PV10_00274	PV10_06724	A0A0D1Y6N2	A0A0D1ZC34	Plus3 domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.927