67 items (Exophiala mesophila) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV10_01746	Uncharacterized protein. (1292 aa)
	PV10_00249	DUF1767 domain-containing protein. (290 aa)
	PV10_00133	Uncharacterized protein. (804 aa)
	PV10_02657	Uncharacterized protein. (791 aa)
	PV10_05074	WD_REPEATS_REGION domain-containing protein. (1017 aa)
	PV10_04656	Serine/threonine-protein phosphatase. (448 aa)
	PV10_04479	zf-C2HE domain-containing protein. (273 aa)
	PV10_04167	Uncharacterized protein. (277 aa)
	PV10_06691	TP6A_N domain-containing protein. (370 aa)
	PV10_06154	SAP domain-containing protein. (684 aa)
	PV10_05932	DNA helicase; Belongs to the MCM family. (963 aa)
	PV10_05818	Poly [ADP-ribose] polymerase. (702 aa)
	PV10_01745	Uncharacterized protein. (871 aa)
	PV10_05344	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (513 aa)
	PV10_01567	DNA polymerase. (1698 aa)
	PV10_01469	DNA helicase; Belongs to the MCM family. (915 aa)
	PV10_07844	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (607 aa)
	PV10_01905	Uncharacterized protein. (514 aa)
	PV10_00814	ERCC4 domain-containing protein. (612 aa)
	PV10_00679	Uncharacterized protein. (659 aa)
	PV10_06819	RECA_2 domain-containing protein. (564 aa)
	PV10_00324	Protein kinase domain-containing protein. (573 aa)
	PV10_08866	MAGE domain-containing protein. (396 aa)
	PV10_00213	Uncharacterized protein. (747 aa)
	PV10_03624	Uncharacterized protein. (363 aa)
	PV10_02860	Uncharacterized protein. (746 aa)
	PV10_03287	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (997 aa)
	PV10_03166	SMC_N domain-containing protein. (1198 aa)
	PV10_05128	Sister chromatid cohesion protein. (1758 aa)
	PV10_03795	ERCC4 domain-containing protein. (651 aa)
	PV10_06519	SP-RING-type domain-containing protein. (511 aa)
	PV10_06514	DNA helicase; Belongs to the MCM family. (1004 aa)
	PV10_05940	Uncharacterized protein. (611 aa)
	PV10_05473	ERCC4 domain-containing protein. (948 aa)
	PV10_08755	Uncharacterized protein. (548 aa)
	PV10_08487	Uncharacterized protein. (377 aa)
	PV10_08813	Uncharacterized protein. (1012 aa)
	PV10_08510	Deacetylase sirtuin-type domain-containing protein. (617 aa)
	PV10_08108	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (706 aa)
	PV10_09167	RECA_2 domain-containing protein. (481 aa)
	PV10_01681	DNA helicase; Belongs to the MCM family. (863 aa)
	PV10_01113	DNA ligase. (870 aa)
	PV10_00499	SMC_N domain-containing protein. (1145 aa)
	B0A52_06663	Uncharacterized protein. (77 aa)
	PV10_03291	DRMBL domain-containing protein. (937 aa)
	PV10_04251	DNA helicase; Belongs to the MCM family. (724 aa)
	PV10_04235	Uncharacterized protein. (609 aa)
	PV10_07867	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (693 aa)
	PV10_07753	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (507 aa)
	PV10_06885	Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family. (723 aa)
	B0A52_04315	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (350 aa)
	PV10_08211	Sld5 domain-containing protein. (236 aa)
	PV10_08508	Uncharacterized protein. (667 aa)
	PV10_08517	BRCT domain-containing protein. (714 aa)
	PV10_08634	Uncharacterized protein. (92 aa)
	PV10_08751	Uncharacterized protein. (945 aa)
	PV10_05603	Checkpoint protein; Belongs to the HUS1 family. (351 aa)
	PV10_05702	Uncharacterized protein. (1460 aa)
	PV10_04341	Uncharacterized protein. (716 aa)
	PV10_04946	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (758 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (808 aa)
	PV10_03455	AAA_23 domain-containing protein. (1306 aa)
	PV10_03632	CBM1 domain-containing protein. (328 aa)
	PV10_00207	Rad51 domain-containing protein. (403 aa)
	PV10_01595	Sld5 domain-containing protein. (182 aa)
	PV10_01600	Deacetylase sirtuin-type domain-containing protein. (625 aa)
	PV10_09193	BRCT domain-containing protein. (497 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A52_04315	B0A52_06663	A0A0D1XLL8	A0A0D1Y5X8	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	Uncharacterized protein.	0.767
B0A52_04315	MCM7	A0A0D1XLL8	A0A0D1WY54	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.542
B0A52_04315	PV10_00133	A0A0D1XLL8	A0A0D2ABD5	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	Uncharacterized protein.	0.982
B0A52_04315	PV10_00207	A0A0D1XLL8	A0A0D1X3C6	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	Rad51 domain-containing protein.	0.925
B0A52_04315	PV10_00213	A0A0D1XLL8	A0A0D1ZNW6	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	Uncharacterized protein.	0.986
B0A52_04315	PV10_00249	A0A0D1XLL8	A0A0D2ABR5	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	DUF1767 domain-containing protein.	0.887
B0A52_04315	PV10_00499	A0A0D1XLL8	A0A0D1Y7G7	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	SMC_N domain-containing protein.	0.792
B0A52_04315	PV10_00814	A0A0D1XLL8	A0A0D1ZT10	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	ERCC4 domain-containing protein.	0.967
B0A52_04315	PV10_01113	A0A0D1XLL8	A0A0D1Y9J9	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	DNA ligase.	0.572
B0A52_04315	PV10_01469	A0A0D1XLL8	A0A0D1ZUV0	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	DNA helicase; Belongs to the MCM family.	0.645
B0A52_04315	PV10_01567	A0A0D1XLL8	A0A0D1ZV56	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	DNA polymerase.	0.895
B0A52_04315	PV10_01595	A0A0D1XLL8	A0A0D1X7Q3	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	Sld5 domain-containing protein.	0.411
B0A52_04315	PV10_01681	A0A0D1XLL8	A0A0D1YBK4	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	DNA helicase; Belongs to the MCM family.	0.780
B0A52_04315	PV10_02657	A0A0D1XLL8	A0A0D2A7I5	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	Uncharacterized protein.	0.842
B0A52_04315	PV10_02860	A0A0D1XLL8	A0A0D1ZMH9	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	Uncharacterized protein.	0.823
B0A52_04315	PV10_03166	A0A0D1XLL8	A0A0D1ZLR2	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	SMC_N domain-containing protein.	0.641
B0A52_04315	PV10_03291	A0A0D1XLL8	A0A0D1Y4S8	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	DRMBL domain-containing protein.	0.484
B0A52_04315	PV10_03455	A0A0D1XLL8	A0A0D1X241	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	AAA_23 domain-containing protein.	0.924
B0A52_04315	PV10_03624	A0A0D1XLL8	A0A0D1ZN74	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	Uncharacterized protein.	0.767
B0A52_04315	PV10_03795	A0A0D1XLL8	A0A0D1ZF97	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	ERCC4 domain-containing protein.	0.517