STRINGSTRING
PV10_04364 PV10_04364 PV10_03326 PV10_03326 PV10_03171 PV10_03171 PV10_08075 PV10_08075 PV10_00036 PV10_00036 PV10_03591 PV10_03591 PV10_03032 PV10_03032 B0A52_02850 B0A52_02850 PV10_02163 PV10_02163 PV10_05173 PV10_05173 PV10_02286 PV10_02286 PV10_02171 PV10_02171 B0A52_02140 B0A52_02140 PV10_04837 PV10_04837 PV10_04671 PV10_04671 PV10_04533 PV10_04533 MDM10 MDM10 PV10_05176 PV10_05176 PV10_05149 PV10_05149 B0A52_04953 B0A52_04953 PV10_03790 PV10_03790 B0A52_08886 B0A52_08886 PV10_06769 PV10_06769 B0A52_07298 B0A52_07298 PV10_06335 PV10_06335 PV10_05593 PV10_05593 PV10_06246 PV10_06246 PV10_06181 PV10_06181 PV10_05447 PV10_05447 PV10_05392 PV10_05392 PV10_05912 PV10_05912 PV10_05687 PV10_05687 PV10_07380 PV10_07380 PV10_07273 PV10_07273 PV10_05368 PV10_05368 B0A52_07118 B0A52_07118 PV10_07020 PV10_07020 PV10_06975 PV10_06975 B0A52_05815 B0A52_05815 PV10_07561 PV10_07561 PV10_07513 PV10_07513 B0A52_01466 B0A52_01466 B0A52_09811 B0A52_09811 PV10_07230 PV10_07230 PV10_08467 PV10_08467 B0A52_09275 B0A52_09275 MMM1 MMM1 PV10_09117 PV10_09117 PV10_08221 PV10_08221 PV10_09019 PV10_09019 PV10_09198 PV10_09198 PV10_01392 PV10_01392 PV10_01379 PV10_01379 PV10_01318 PV10_01318 PV10_01217 PV10_01217 PV10_01161 PV10_01161 PV10_00724 PV10_00724 PV10_00484 PV10_00484 PV10_03246 PV10_03246 PV10_02170 PV10_02170 PV10_05108 PV10_05108 PV10_03812 PV10_03812 PV10_06808 PV10_06808 PV10_06313 PV10_06313 PV10_07877 PV10_07877 PV10_07644 PV10_07644 PV10_08091 PV10_08091 PV10_07938 PV10_07938 PV10_01855 PV10_01855 PV10_01535 PV10_01535 B0A52_08325 B0A52_08325 PV10_00447 PV10_00447 PV10_00053 PV10_00053 MDM12 MDM12 PV10_03510 PV10_03510 PV10_02832 PV10_02832 PV10_02395 PV10_02395 PV10_02258 PV10_02258 PV10_04994 PV10_04994 PV10_04860 PV10_04860 PV10_08339 PV10_08339 PV10_04270 PV10_04270 B0A52_03182 B0A52_03182 PV10_03972 PV10_03972 PV10_06683 PV10_06683 B0A52_03437 B0A52_03437 PV10_05782 PV10_05782 B0A52_06876 B0A52_06876 PV10_07828 PV10_07828 PV10_08090 PV10_08090 PV10_00392 PV10_00392 PV10_08441 PV10_08441 PV10_08446 PV10_08446 PV10_00574 PV10_00574 PV10_01242 PV10_01242 PV10_00900 PV10_00900 PV10_01021 PV10_01021 PV10_07835 PV10_07835 PV10_01584 PV10_01584 PV10_05578 PV10_05578 PV10_05643 PV10_05643 PV10_05661 PV10_05661 PV10_05843 PV10_05843 PV10_06009 PV10_06009 PV10_03682 PV10_03682 PV10_04536 PV10_04536 PV10_04760 PV10_04760 PV10_04892 PV10_04892 PV10_04992 PV10_04992 PV10_02550 PV10_02550 PFA4 PFA4 PV10_00280 PV10_00280 PV10_00437 PV10_00437 PV10_00746 PV10_00746 PV10_01085 PV10_01085 PV10_01115 PV10_01115 PV10_01219 PV10_01219 PV10_01342 PV10_01342
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PV10_04364Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (526 aa)
PV10_03326Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (608 aa)
PV10_03171Uncharacterized protein. (205 aa)
PV10_08075Uncharacterized protein. (416 aa)
PV10_00036MPN domain-containing protein. (492 aa)
PV10_03591Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family. (646 aa)
PV10_03032Uncharacterized protein. (173 aa)
B0A52_02850Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (389 aa)
PV10_02163Uncharacterized protein. (1241 aa)
PV10_05173SRP9-21 domain-containing protein. (166 aa)
PV10_02286AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1044 aa)
PV10_02171Uncharacterized protein. (551 aa)
B0A52_02140Uncharacterized protein. (192 aa)
PV10_04837Pex2_Pex12 domain-containing protein. (469 aa)
PV10_04671Mitochondrial inner membrane protease subunit. (213 aa)
PV10_04533Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (830 aa)
MDM10Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...] (513 aa)
PV10_05176Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (579 aa)
PV10_05149Adaptin_N domain-containing protein. (828 aa)
B0A52_04953Uncharacterized protein. (171 aa)
PV10_03790Uncharacterized protein. (447 aa)
B0A52_08886V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (161 aa)
PV10_06769Uncharacterized protein. (143 aa)
B0A52_07298Ubiquitin-conjugating enzyme E2 13; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
PV10_06335Chaperone DnaK; Belongs to the heat shock protein 70 family. (678 aa)
PV10_05593Uncharacterized protein. (541 aa)
PV10_06246Uncharacterized protein. (602 aa)
PV10_06181RING-type domain-containing protein. (398 aa)
PV10_05447Uncharacterized protein. (353 aa)
PV10_05392Uncharacterized protein. (361 aa)
PV10_05912Zn(2)-C6 fungal-type domain-containing protein. (715 aa)
PV10_05687Uncharacterized protein. (350 aa)
PV10_07380AAA domain-containing protein; Belongs to the AAA ATPase family. (417 aa)
PV10_07273Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (255 aa)
PV10_05368WSC domain-containing protein. (406 aa)
B0A52_07118Mitochondrial import inner membrane translocase subunit tim16. (140 aa)
PV10_07020Bac_surface_Ag domain-containing protein. (529 aa)
PV10_06975GLUE N-terminal domain-containing protein. (611 aa)
B0A52_05815Mitochondrial import inner membrane translocase subunit tim17. (155 aa)
PV10_07561Uncharacterized protein. (258 aa)
PV10_07513Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (244 aa)
B0A52_01466Uncharacterized protein. (206 aa)
B0A52_09811Uncharacterized protein. (258 aa)
PV10_07230Uncharacterized membrane protein. (181 aa)
PV10_08467Uncharacterized protein. (188 aa)
B0A52_09275ADP-ribosylation factor-like protein 1; Belongs to the small GTPase superfamily. Arf family. (182 aa)
MMM1Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] (503 aa)
PV10_09117Uncharacterized protein. (108 aa)
PV10_08221Mitochondrial import inner membrane translocase subunit tim14. (107 aa)
PV10_09019Uncharacterized protein. (764 aa)
PV10_09198Uncharacterized protein. (311 aa)
PV10_01392Uncharacterized protein. (623 aa)
PV10_01379V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (163 aa)
PV10_01318Uncharacterized protein. (286 aa)
PV10_01217Mitochondrial inner membrane protease subunit. (457 aa)
PV10_01161Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (121 aa)
PV10_00724Uncharacterized protein. (113 aa)
PV10_00484Mitochondrial-processing peptidase subunit beta; Belongs to the peptidase M16 family. (478 aa)
PV10_03246SH3 domain-containing protein. (480 aa)
PV10_02170Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. (343 aa)
PV10_05108Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256|PROSITE-. (932 aa)
PV10_03812Uncharacterized protein. (1662 aa)
PV10_06808Signal peptidase subunit 3. (260 aa)
PV10_06313Uncharacterized protein. (245 aa)
PV10_07877Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (417 aa)
PV10_07644TPR_REGION domain-containing protein. (649 aa)
PV10_08091UBIQUITIN_CONJUGAT_2 domain-containing protein. (139 aa)
PV10_07938Uncharacterized protein. (776 aa)
PV10_01855Uncharacterized protein. (410 aa)
PV10_01535Uncharacterized protein. (220 aa)
B0A52_08325Mitochondrial import inner membrane translocase subunit tim10. (98 aa)
PV10_00447Uncharacterized protein. (826 aa)
PV10_00053Sulfhydryl oxidase. (206 aa)
MDM12Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...] (457 aa)
PV10_03510Uncharacterized protein. (591 aa)
PV10_02832Uncharacterized protein. (585 aa)
PV10_02395J domain-containing protein. (510 aa)
PV10_02258Uncharacterized protein. (346 aa)
PV10_04994Uncharacterized protein; Belongs to the GroES chaperonin family. (107 aa)
PV10_04860Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (576 aa)
PV10_08339Uncharacterized protein. (424 aa)
PV10_04270CHY-type domain-containing protein. (122 aa)
B0A52_03182Vacuolar protein sorting-associated protein 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (709 aa)
PV10_03972ATP-dependent Clp protease, ATP-binding subunit ClpX. (626 aa)
PV10_06683DNL-type domain-containing protein. (194 aa)
B0A52_03437Protein transport protein SEC61 subunit alpha; Belongs to the SecY/SEC61-alpha family. (476 aa)
PV10_05782Uncharacterized protein. (102 aa)
B0A52_06876Uncharacterized protein. (54 aa)
PV10_07828Mitochondrial intermediate peptidase. (795 aa)
PV10_08090Uncharacterized protein. (1723 aa)
PV10_00392Uncharacterized protein. (618 aa)
PV10_08441Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (521 aa)
PV10_08446TPR_REGION domain-containing protein. (376 aa)
PV10_00574Uncharacterized protein. (304 aa)
PV10_01242Vacuolar protein sorting-associated protein; May be involved in recycling of membrane proteins between an endocytic compartment and the TGN; Belongs to the VPS13 family. (3177 aa)
PV10_00900Uncharacterized protein. (339 aa)
PV10_01021Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (636 aa)
PV10_07835zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family. (136 aa)
PV10_01584Uncharacterized protein; Belongs to the GrpE family. (268 aa)
PV10_05578Uncharacterized protein. (774 aa)
PV10_05643Erf4 domain-containing protein. (291 aa)
PV10_05661SRP54 domain-containing protein. (654 aa)
PV10_05843Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (577 aa)
PV10_06009Autophagy-related protein 3. (371 aa)
PV10_03682Uncharacterized protein. (779 aa)
PV10_04536Uncharacterized protein; Belongs to the peptidase M16 family. (566 aa)
PV10_04760Uncharacterized protein. (152 aa)
PV10_04892CFEM domain-containing protein. (430 aa)
PV10_04992Uncharacterized protein. (172 aa)
PV10_02550Pex14_N domain-containing protein. (377 aa)
PFA4Palmitoyltransferase PFA4; Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function; Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily. (422 aa)
PV10_00280Uncharacterized protein. (145 aa)
PV10_00437Uncharacterized protein. (1309 aa)
PV10_00746Pex2_Pex12 domain-containing protein. (448 aa)
PV10_01085Uncharacterized protein. (319 aa)
PV10_01115J domain-containing protein. (718 aa)
PV10_01219UBIQUITIN_CONJUGAT_2 domain-containing protein. (258 aa)
PV10_01342WD_REPEATS_REGION domain-containing protein. (341 aa)
Your Current Organism:
Exophiala mesophila
NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.