85 items (Exophiala mesophila) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV10_05742	Uncharacterized protein. (1739 aa)
	PV10_05758	Uncharacterized protein. (468 aa)
	PV10_06324	Uncharacterized protein. (421 aa)
	PV10_05696	Uncharacterized protein. (1016 aa)
	PV10_07821	TAP-C domain-containing protein. (411 aa)
	PV10_07803	Importin N-terminal domain-containing protein. (1086 aa)
	PV10_07470	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (659 aa)
	PV10_07349	Uncharacterized protein. (1120 aa)
	PV10_05390	Uncharacterized protein. (849 aa)
	PV10_07049	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (745 aa)
	TIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (248 aa)
	PV10_07556	SAP domain-containing protein. (306 aa)
	B0A52_01817	RPOL4c domain-containing protein. (152 aa)
	B0A52_05243	40S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (266 aa)
	PV10_08306	Uncharacterized protein. (575 aa)
	PV10_08034	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (970 aa)
	PV10_01522	ABC transporter ATP-binding protein ARB1. (628 aa)
	PV10_01518	Importin N-terminal domain-containing protein. (1099 aa)
	PV10_06546	Uncharacterized protein. (654 aa)
	PV10_04199	Uncharacterized protein. (652 aa)
	PV10_04262	Uncharacterized protein. (613 aa)
	PV10_04385	Uncharacterized protein. (108 aa)
	PV10_04625	GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (297 aa)
	PV10_04852	Importin N-terminal domain-containing protein. (952 aa)
	PV10_04766	GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (368 aa)
	B0A52_07938	Uncharacterized protein. (272 aa)
	PV10_02426	Uncharacterized protein. (757 aa)
	PV10_02168	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (233 aa)
	PV10_02383	Importin N-terminal domain-containing protein. (1097 aa)
	PV10_02678	Uncharacterized protein. (547 aa)
	PV10_09190	Nup188_C domain-containing protein. (1825 aa)
	PV10_02989	Protein kinase domain-containing protein. (795 aa)
	PV10_08002	Translation initiation factor RLI1. (604 aa)
	PV10_03215	Uncharacterized protein. (315 aa)
	PV10_00520	Uncharacterized protein. (549 aa)
	PV10_00654	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1427 aa)
	PV10_00929	LisH domain-containing protein. (426 aa)
	PV10_00497	Uncharacterized protein. (1274 aa)
	PV10_07156	Uncharacterized protein. (763 aa)
	PV10_00693	PCI domain-containing protein. (462 aa)
	PV10_00747	Importin N-terminal domain-containing protein. (1051 aa)
	B0A52_08726	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (217 aa)
	PV10_01597	TPR_MLP1_2 domain-containing protein. (2027 aa)
	PV10_01373	CP-type G domain-containing protein. (550 aa)
	PV10_07807	Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (1032 aa)
	PV10_01839	Peptidase S59 domain-containing protein. (1954 aa)
	PV10_05757	CP-type G domain-containing protein. (674 aa)
	PV10_06388	Uncharacterized protein. (937 aa)
	PV10_06700	TFIIS N-terminal domain-containing protein. (401 aa)
	PV10_04602	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (429 aa)
	PV10_04844	Importin N-terminal domain-containing protein. (1059 aa)
	PV10_04883	RRM domain-containing protein. (252 aa)
	PV10_04987	DUF775 domain-containing protein. (187 aa)
	B0A52_04130	Nucleoporin GLE2. (362 aa)
	PV10_00254	Xpo1 domain-containing protein. (1268 aa)
	PV10_00295	J domain-containing protein. (447 aa)
	PV10_00501	U3 small nucleolar RNA-associated protein 22. (1140 aa)
	PV10_00579	FHA domain-containing protein. (375 aa)
	PV10_00707	Uncharacterized protein. (242 aa)
	PV10_01003	Importin N-terminal domain-containing protein. (1051 aa)
	PV10_08143	Uncharacterized protein. (1260 aa)
	PV10_08458	Uncharacterized protein. (1323 aa)
	PV10_08634	Uncharacterized protein. (92 aa)
	B0A52_09281	40S ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (215 aa)
	PV10_06133	Uncharacterized protein. (2337 aa)
	PV10_06239	Uncharacterized protein. (424 aa)
	PV10_04191	RanBD1 domain-containing protein. (263 aa)
	PV10_05165	NTF2 domain-containing protein. (125 aa)
	PV10_02173	Uncharacterized protein. (1117 aa)
	PV10_02999	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (580 aa)
	PV10_03245	RRM domain-containing protein. (427 aa)
	PV10_01245	Uncharacterized protein; Belongs to the DEAD box helicase family. (516 aa)
	PV10_08406	WD_REPEATS_REGION domain-containing protein. (347 aa)
	PV10_08444	Uncharacterized protein. (809 aa)
	PV10_07229	Uncharacterized protein. (1365 aa)
	PV10_05513	Importin N-terminal domain-containing protein. (959 aa)
	PV10_06632	Uncharacterized protein. (433 aa)
	PV10_04930	Importin N-terminal domain-containing protein. (974 aa)
	PV10_05121	Importin subunit alpha; Belongs to the importin alpha family. (552 aa)
	PV10_05223	Uncharacterized protein. (336 aa)
	PV10_02459	Uncharacterized protein. (214 aa)
	PV10_00131	C2H2-type domain-containing protein. (118 aa)
	PV10_00137	Uncharacterized protein. (487 aa)
	PV10_00608	Nsp1_C domain-containing protein. (694 aa)
	PV10_00863	Importin N-terminal domain-containing protein. (873 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A52_01817	B0A52_08726	A0A0D1Z4K7	A0A0D1ZT38	RPOL4c domain-containing protein.	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.657
B0A52_01817	PV10_00137	A0A0D1Z4K7	A0A0D1Y6D3	RPOL4c domain-containing protein.	Uncharacterized protein.	0.663
B0A52_01817	PV10_00654	A0A0D1Z4K7	A0A0D1ZQE5	RPOL4c domain-containing protein.	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	0.958
B0A52_01817	PV10_00929	A0A0D1Z4K7	A0A0D1ZRB7	RPOL4c domain-containing protein.	LisH domain-containing protein.	0.489
B0A52_01817	PV10_03245	A0A0D1Z4K7	A0A0D1X1H6	RPOL4c domain-containing protein.	RRM domain-containing protein.	0.663
B0A52_01817	PV10_04262	A0A0D1Z4K7	A0A0D1ZEB3	RPOL4c domain-containing protein.	Uncharacterized protein.	0.721
B0A52_01817	PV10_04625	A0A0D1Z4K7	A0A0D1ZF91	RPOL4c domain-containing protein.	GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	0.715
B0A52_01817	PV10_06133	A0A0D1Z4K7	A0A0D1WR75	RPOL4c domain-containing protein.	Uncharacterized protein.	0.486
B0A52_01817	PV10_06700	A0A0D1Z4K7	A0A0D1ZZH2	RPOL4c domain-containing protein.	TFIIS N-terminal domain-containing protein.	0.666
B0A52_04130	B0A52_08726	A0A0D2A9U4	A0A0D1ZT38	Nucleoporin GLE2.	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.702
B0A52_04130	PV10_00137	A0A0D2A9U4	A0A0D1Y6D3	Nucleoporin GLE2.	Uncharacterized protein.	0.430
B0A52_04130	PV10_00254	A0A0D2A9U4	A0A0D2ABS1	Nucleoporin GLE2.	Xpo1 domain-containing protein.	0.473
B0A52_04130	PV10_00497	A0A0D2A9U4	A0A0D1ZRS5	Nucleoporin GLE2.	Uncharacterized protein.	0.640
B0A52_04130	PV10_00608	A0A0D2A9U4	A0A0D1Y7P8	Nucleoporin GLE2.	Nsp1_C domain-containing protein.	0.926
B0A52_04130	PV10_00693	A0A0D2A9U4	A0A0D1ZSI6	Nucleoporin GLE2.	PCI domain-containing protein.	0.527
B0A52_04130	PV10_00863	A0A0D2A9U4	A0A0D1Y8U2	Nucleoporin GLE2.	Importin N-terminal domain-containing protein.	0.670
B0A52_04130	PV10_01003	A0A0D2A9U4	A0A0D2AE98	Nucleoporin GLE2.	Importin N-terminal domain-containing protein.	0.654
B0A52_04130	PV10_01245	A0A0D2A9U4	A0A0D1X6P9	Nucleoporin GLE2.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.528
B0A52_04130	PV10_01518	A0A0D2A9U4	A0A0D1YAZ6	Nucleoporin GLE2.	Importin N-terminal domain-containing protein.	0.642
B0A52_04130	PV10_01597	A0A0D2A9U4	A0A0D1ZTJ6	Nucleoporin GLE2.	TPR_MLP1_2 domain-containing protein.	0.989