79 items (Exophiala mesophila) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV10_00589	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (460 aa)
	PV10_06015	Uncharacterized protein. (211 aa)
	B0A52_02604	Putative cytochrome b5; Belongs to the cytochrome b5 family. (84 aa)
	PV10_04938	Abhydrolase_3 domain-containing protein. (357 aa)
	PV10_02082	Uncharacterized protein. (313 aa)
	PV10_02305	Uncharacterized protein. (348 aa)
	PV10_03460	Uncharacterized protein. (287 aa)
	PV10_03562	3-hydroxy-3-methylglutaryl coenzyme A reductase. (1150 aa)
	PV10_00251	Uncharacterized protein. (774 aa)
	PV10_00292	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (384 aa)
	PV10_00421	PH domain-containing protein. (1453 aa)
	PV10_00834	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (408 aa)
	PV10_01765	Uncharacterized protein. (446 aa)
	PV10_08971	O-acyltransferase. (547 aa)
	PV10_07716	Uncharacterized protein. (307 aa)
	PV10_05303	S5A_REDUCTASE domain-containing protein. (264 aa)
	PV10_05418	SE domain-containing protein. (491 aa)
	PV10_05836	FAD-binding FR-type domain-containing protein. (423 aa)
	PV10_05916	Uncharacterized protein. (605 aa)
	PV10_06603	Uncharacterized protein. (388 aa)
	PV10_06670	Glyco_transf_28 domain-containing protein. (1089 aa)
	PV10_06689	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (740 aa)
	PV10_04428	Uncharacterized protein. (196 aa)
	PV10_04891	Uncharacterized protein; Belongs to the cytochrome P450 family. (520 aa)
	PV10_02396	Farnesyl-diphosphate farnesyltransferase. (489 aa)
	PV10_00680	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (333 aa)
	PV10_01308	Epimerase domain-containing protein. (397 aa)
	PV10_09029	Uncharacterized protein. (485 aa)
	PV10_09139	Glyco_transf_28 domain-containing protein. (987 aa)
	PV10_08083	Uncharacterized protein. (366 aa)
	PV10_07974	Zn(2)-C6 fungal-type domain-containing protein. (748 aa)
	PV10_08749	Uncharacterized protein. (789 aa)
	PV10_08205	Uncharacterized protein. (233 aa)
	PV10_06882	Glyco_transf_28 domain-containing protein. (1340 aa)
	PV10_07257	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (297 aa)
	PV10_07632	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (136 aa)
	PV10_06825	Uncharacterized protein. (146 aa)
	PV10_05612	AlcB domain-containing protein. (454 aa)
	PV10_05301	ABM domain-containing protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
	PV10_05618	Uncharacterized protein. (2021 aa)
	PV10_06506	3Beta_HSD domain-containing protein. (429 aa)
	PV10_06749	Uncharacterized protein. (304 aa)
	PV10_06155	AB hydrolase-1 domain-containing protein. (696 aa)
	PV10_06227	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (413 aa)
	PV10_04126	Uncharacterized protein. (355 aa)
	PV10_06729	Uncharacterized protein; Belongs to the cytochrome P450 family. (523 aa)
	PV10_06781	Uncharacterized protein. (587 aa)
	cprA	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (691 aa)
	PV10_04259	Fungal_trans domain-containing protein. (654 aa)
	PV10_05185	Uncharacterized protein. (264 aa)
	PV10_05058	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family. (340 aa)
	PV10_05192	Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (530 aa)
	PV10_02651	Uncharacterized protein. (403 aa)
	PV10_02085	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (502 aa)
	PV10_00064	FAD-binding PCMH-type domain-containing protein. (533 aa)
	PV10_03289	Abhydro_lipase domain-containing protein. (698 aa)
	PV10_08263	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (461 aa)
	PV10_00466	Uncharacterized protein. (395 aa)
	PV10_01064	Uncharacterized protein; Belongs to the cytochrome P450 family. (276 aa)
	PV10_07420	EXPERA domain-containing protein. (260 aa)
	PV10_01812	Uncharacterized protein. (813 aa)
	PV10_01368	EXPERA domain-containing protein. (262 aa)
	PV10_01654	Uncharacterized protein; Belongs to the cytochrome P450 family. (532 aa)
	PV10_05613	Uncharacterized protein. (601 aa)
	PV10_06480	Glyco_transf_28 domain-containing protein. (950 aa)
	PV10_05163	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (463 aa)
	PV10_05186	FAD_binding_2 domain-containing protein. (594 aa)
	PV10_02323	Uncharacterized protein; Belongs to the cytochrome P450 family. (538 aa)
	PV10_02877	Uncharacterized protein. (877 aa)
	PV10_05981	Uncharacterized protein. (288 aa)
	PV10_01139	Uncharacterized protein. (318 aa)
	PV10_01320	Uncharacterized protein; Belongs to the cytochrome P450 family. (558 aa)
	PV10_08530	Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (397 aa)
	PV10_08709	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (457 aa)
	PV10_08920	Uncharacterized protein. (259 aa)
	PV10_07081	Uncharacterized protein. (613 aa)
	PV10_07417	O-acyltransferase. (512 aa)
	PV10_05598	Uncharacterized protein. (267 aa)
	PV10_05650	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (357 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A52_02604	PV10_00680	A0A0D1WRM7	A0A0D1Y7Y8	Putative cytochrome b5; Belongs to the cytochrome b5 family.	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.535
B0A52_02604	PV10_04126	A0A0D1WRM7	A0A0D1ZDS4	Putative cytochrome b5; Belongs to the cytochrome b5 family.	Uncharacterized protein.	0.484
B0A52_02604	PV10_05836	A0A0D1WRM7	A0A0D1XT11	Putative cytochrome b5; Belongs to the cytochrome b5 family.	FAD-binding FR-type domain-containing protein.	0.484
PV10_00064	PV10_00292	A0A0D1ZNF2	A0A0D1X3M6	FAD-binding PCMH-type domain-containing protein.	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.	0.771
PV10_00064	PV10_00834	A0A0D1ZNF2	A0A0D1X5K6	FAD-binding PCMH-type domain-containing protein.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.853
PV10_00064	PV10_01064	A0A0D1ZNF2	A0A0D1ZRR5	FAD-binding PCMH-type domain-containing protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.632
PV10_00064	PV10_01308	A0A0D1ZNF2	A0A0D1YAF1	FAD-binding PCMH-type domain-containing protein.	Epimerase domain-containing protein.	0.459
PV10_00064	PV10_01368	A0A0D1ZNF2	A0A0D1ZUM1	FAD-binding PCMH-type domain-containing protein.	EXPERA domain-containing protein.	0.840
PV10_00064	PV10_01765	A0A0D1ZNF2	A0A0D1X828	FAD-binding PCMH-type domain-containing protein.	Uncharacterized protein.	0.876
PV10_00064	PV10_01812	A0A0D1ZNF2	A0A0D1ZUB8	FAD-binding PCMH-type domain-containing protein.	Uncharacterized protein.	0.406
PV10_00064	PV10_02082	A0A0D1ZNF2	A0A0D1WXW7	FAD-binding PCMH-type domain-containing protein.	Uncharacterized protein.	0.553
PV10_00064	PV10_02085	A0A0D1ZNF2	A0A0D1ZK53	FAD-binding PCMH-type domain-containing protein.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.444
PV10_00064	PV10_02323	A0A0D1ZNF2	A0A0D2A6H8	FAD-binding PCMH-type domain-containing protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.924
PV10_00064	PV10_02396	A0A0D1ZNF2	A0A0D1Y269	FAD-binding PCMH-type domain-containing protein.	Farnesyl-diphosphate farnesyltransferase.	0.530
PV10_00064	PV10_02651	A0A0D1ZNF2	A0A0D1ZK15	FAD-binding PCMH-type domain-containing protein.	Uncharacterized protein.	0.553
PV10_00064	PV10_02877	A0A0D1ZNF2	A0A0D2A888	FAD-binding PCMH-type domain-containing protein.	Uncharacterized protein.	0.553
PV10_00064	PV10_03562	A0A0D1ZNF2	A0A0D1X2I7	FAD-binding PCMH-type domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.551
PV10_00064	PV10_04259	A0A0D1ZNF2	A0A0D1ZGX8	FAD-binding PCMH-type domain-containing protein.	Fungal_trans domain-containing protein.	0.632
PV10_00064	PV10_04891	A0A0D1ZNF2	A0A0D1XZJ9	FAD-binding PCMH-type domain-containing protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.791
PV10_00064	PV10_05058	A0A0D1ZNF2	A0A0D1ZIW9	FAD-binding PCMH-type domain-containing protein.	Methyltransf_11 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.	0.702