111 items (Exophiala mesophila) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV10_07764	Ubiquitin carboxyl-terminal hydrolase. (730 aa)
	PV10_09064	Uncharacterized protein; Belongs to the DEAD box helicase family. (617 aa)
	B0A52_08533	60S ribosomal protein L16; Belongs to the universal ribosomal protein uL13 family. (201 aa)
	PV10_08910	Uncharacterized protein. (790 aa)
	PV10_08958	Protein kinase domain-containing protein. (1183 aa)
	PV10_07630	Chromo domain-containing protein. (241 aa)
	PV10_07634	Non-specific serine/threonine protein kinase. (871 aa)
	PV10_05706	Uncharacterized protein. (697 aa)
	PV10_06602	Uncharacterized protein. (255 aa)
	PV10_03996	Uncharacterized protein. (390 aa)
	PV10_04104	PUM-HD domain-containing protein. (739 aa)
	PV10_04838	Uncharacterized protein. (352 aa)
	PV10_05020	Protein kinase domain-containing protein. (739 aa)
	PAN3	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...] (639 aa)
	PV10_00498	ATP-dependent RNA helicase DHH1; Belongs to the DEAD box helicase family. (512 aa)
	PV10_01197	PAP-associated domain-containing protein. (1323 aa)
	PV10_01600	Deacetylase sirtuin-type domain-containing protein. (625 aa)
	PV10_01631	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1258 aa)
	PV10_01820	Uncharacterized protein. (725 aa)
	PV10_01896	Uncharacterized protein. (684 aa)
	PV10_07971	Cell differentiation protein rcd1. (415 aa)
	PV10_08216	Rtt106 domain-containing protein. (522 aa)
	PV10_08324	SANT_DAMP1_like domain-containing protein. (858 aa)
	PV10_08664	PUM-HD domain-containing protein. (660 aa)
	PV10_06831	Uncharacterized protein. (432 aa)
	PV10_07141	Endo/exonuclease/phosphatase domain-containing protein. (749 aa)
	B0A52_01899	CBFD_NFYB_HMF domain-containing protein. (163 aa)
	PV10_06162	UV excision repair protein Rad23. (398 aa)
	PV10_06563	W2 domain-containing protein. (428 aa)
	PV10_04896	Uncharacterized protein. (874 aa)
	PV10_02193	Uncharacterized protein. (629 aa)
	PAN2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1169 aa)
	PV10_03134	Uncharacterized protein. (475 aa)
	PV10_03145	Thioredoxin-like_fold domain-containing protein. (210 aa)
	PV10_03314	FAS1 domain-containing protein. (236 aa)
	PV10_03590	Uncharacterized protein. (606 aa)
	PV10_00274	Plus3 domain-containing protein. (606 aa)
	PV10_00565	HRDC domain-containing protein. (840 aa)
	PV10_00663	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (706 aa)
	PV10_01420	RNase_PH domain-containing protein. (272 aa)
	PV10_01438	GFO_IDH_MocA domain-containing protein. (368 aa)
	PV10_09129	Uncharacterized protein. (815 aa)
	PV10_08243	KH_dom_type_1 domain-containing protein. (245 aa)
	PV10_08510	Deacetylase sirtuin-type domain-containing protein. (617 aa)
	PV10_08563	Deacetylase sirtuin-type domain-containing protein. (550 aa)
	PV10_08965	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (355 aa)
	PV10_08386	Uncharacterized protein. (441 aa)
	PV10_08467	Uncharacterized protein. (188 aa)
	B0A52_01817	RPOL4c domain-containing protein. (152 aa)
	PV10_07172	Uncharacterized protein. (700 aa)
	PV10_07628	DUF1752 domain-containing protein. (549 aa)
	PV10_08948	Uncharacterized protein. (1891 aa)
	PV10_07273	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (255 aa)
	PV10_07325	Ribosomal protein L13. (173 aa)
	PV10_05756	RNase_PH domain-containing protein. (367 aa)
	PV10_07826	C2H2-type domain-containing protein. (830 aa)
	PV10_05826	WD_REPEATS_REGION domain-containing protein. (335 aa)
	PV10_05373	Uncharacterized protein. (469 aa)
	PV10_05387	WD_REPEATS_REGION domain-containing protein. (625 aa)
	PV10_06158	Uncharacterized protein. (964 aa)
	PV10_06230	Uncharacterized protein. (481 aa)
	PV10_06278	Uncharacterized protein. (1097 aa)
	PV10_05722	PUM-HD domain-containing protein. (931 aa)
	PV10_06349	WD_REPEATS_REGION domain-containing protein. (635 aa)
	PV10_05800	Non-specific serine/threonine protein kinase. (892 aa)
	PV10_06789	NmrA domain-containing protein. (367 aa)
	PV10_03930	Uncharacterized protein. (488 aa)
	PV10_04026	Uncharacterized protein. (1516 aa)
	PV10_04073	Uncharacterized protein. (586 aa)
	PV10_04097	PUM-HD domain-containing protein. (999 aa)
	PV10_04176	Uncharacterized protein. (112 aa)
	PV10_06673	HECT domain-containing protein. (1960 aa)
	PV10_04484	PAT1 domain-containing protein. (808 aa)
	PV10_03942	HDAC_interact domain-containing protein. (1518 aa)
	PV10_04790	Uncharacterized protein. (250 aa)
	PV10_05122	Telo_bind domain-containing protein. (670 aa)
	PV10_05158	Nudix hydrolase domain-containing protein. (864 aa)
	PV10_02121	R3H domain-containing protein. (1101 aa)
	PV10_02813	Uncharacterized protein. (294 aa)
	PV10_00253	Uncharacterized protein. (119 aa)
	PV10_03389	CBFD_NFYB_HMF domain-containing protein. (359 aa)
	PV10_03415	Uncharacterized protein. (255 aa)
	PV10_08295	Uncharacterized protein. (485 aa)
	PV10_08461	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (452 aa)
	PV10_00043	ECR1_N domain-containing protein. (377 aa)
	PV10_00070	Uncharacterized protein. (184 aa)
	PV10_00654	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1427 aa)
	PV10_00730	Uncharacterized protein. (631 aa)
	PV10_08759	Uncharacterized protein. (1132 aa)
	PV10_00787	Uncharacterized protein. (2334 aa)
	PV10_00881	Uncharacterized protein. (284 aa)
	PV10_01028	Uncharacterized protein. (1077 aa)
	PV10_00890	TPR_REGION domain-containing protein. (798 aa)
	PV10_01573	RNase_PH domain-containing protein. (361 aa)
	PV10_01618	Uncharacterized protein. (356 aa)
	PV10_07524	Tr-type G domain-containing protein. (701 aa)
	PV10_05344	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (513 aa)
	PV10_01689	Nitrogen regulatory protein DAL80. (258 aa)
	PV10_01722	WD_REPEATS_REGION domain-containing protein. (548 aa)
	PV10_01824	Uncharacterized protein. (1197 aa)
	PV10_01931	Uncharacterized protein. (451 aa)
	PV10_05909	Uncharacterized protein. (336 aa)
	PV10_03887	Chromo domain-containing protein. (1126 aa)
	B0A52_04813	Guanine nucleotide-binding protein subunit beta-like protein. (316 aa)
	PV10_02304	zf-LYAR domain-containing protein. (539 aa)
	PV10_03067	ATP-dependent RNA helicase ded1, variant; Belongs to the DEAD box helicase family. (684 aa)
	PV10_03489	Hist_deacetyl domain-containing protein. (367 aa)
	PV10_00665	NTP_transf_9 domain-containing protein. (342 aa)
	LSM1	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation. (188 aa)
	PV10_01010	SAM domain-containing protein. (616 aa)
	PV10_01136	Protein kinase domain-containing protein. (676 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A52_01817	PV10_00274	A0A0D1Z4K7	A0A0D1Y6N2	RPOL4c domain-containing protein.	Plus3 domain-containing protein.	0.927
B0A52_01817	PV10_00654	A0A0D1Z4K7	A0A0D1ZQE5	RPOL4c domain-containing protein.	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	0.958
B0A52_01817	PV10_00663	A0A0D1Z4K7	A0A0D1Y7V8	RPOL4c domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.900
B0A52_01817	PV10_00890	A0A0D1Z4K7	A0A0D1ZT70	RPOL4c domain-containing protein.	TPR_REGION domain-containing protein.	0.705
B0A52_01817	PV10_01824	A0A0D1Z4K7	A0A0D1ZVW1	RPOL4c domain-containing protein.	Uncharacterized protein.	0.658
B0A52_01817	PV10_01896	A0A0D1Z4K7	A0A0D1X8A3	RPOL4c domain-containing protein.	Uncharacterized protein.	0.694
B0A52_01817	PV10_01931	A0A0D1Z4K7	A0A0D1ZW60	RPOL4c domain-containing protein.	Uncharacterized protein.	0.658
B0A52_01817	PV10_05344	A0A0D1Z4K7	A0A0D1ZV62	RPOL4c domain-containing protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.732
B0A52_01817	PV10_05387	A0A0D1Z4K7	A0A0D1Z9T5	RPOL4c domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.486
B0A52_01817	PV10_06158	A0A0D1Z4K7	A0A0D1ZAD5	RPOL4c domain-containing protein.	Uncharacterized protein.	0.658
B0A52_01817	PV10_06162	A0A0D1Z4K7	A0A0D1XTY3	RPOL4c domain-containing protein.	UV excision repair protein Rad23.	0.595
B0A52_01817	PV10_06278	A0A0D1Z4K7	A0A0D1ZAR5	RPOL4c domain-containing protein.	Uncharacterized protein.	0.658
B0A52_01817	PV10_06349	A0A0D1Z4K7	A0A0D1ZAZ8	RPOL4c domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.694
B0A52_01899	PV10_03389	A0A0D1XQK4	A0A0D1ZP68	CBFD_NFYB_HMF domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.990
B0A52_01899	PV10_05387	A0A0D1XQK4	A0A0D1Z9T5	CBFD_NFYB_HMF domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.780
B0A52_01899	PV10_08948	A0A0D1XQK4	A0A0D1Z652	CBFD_NFYB_HMF domain-containing protein.	Uncharacterized protein.	0.902
B0A52_04813	B0A52_08533	A0A0D2A1U3	A0A0D1WI58	Guanine nucleotide-binding protein subunit beta-like protein.	60S ribosomal protein L16; Belongs to the universal ribosomal protein uL13 family.	0.998
B0A52_04813	PV10_00730	A0A0D2A1U3	A0A0D1ZQQ2	Guanine nucleotide-binding protein subunit beta-like protein.	Uncharacterized protein.	0.603
B0A52_04813	PV10_02121	A0A0D2A1U3	A0A0D1ZIB0	Guanine nucleotide-binding protein subunit beta-like protein.	R3H domain-containing protein.	0.724
B0A52_04813	PV10_02304	A0A0D2A1U3	A0A0D2A6G7	Guanine nucleotide-binding protein subunit beta-like protein.	zf-LYAR domain-containing protein.	0.749