(12 nodes) RNA polymerase II general transcription initiation factor activity network (Exophiala mesophila)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV10_01196	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (705 aa)
	B0A52_07467	TFIIB-type domain-containing protein. (361 aa)
	PV10_00205	TAF8_C domain-containing protein. (323 aa)
	B0A52_06028	TATA-box-binding protein, variant. (257 aa)
	PV10_01598	TFIIE beta domain-containing protein. (233 aa)
	PV10_04433	DUF3591 domain-containing protein. (1125 aa)
	PV10_03216	Uncharacterized protein. (362 aa)
	PV10_00388	Uncharacterized protein. (78 aa)
	PV10_07636	BTB domain-containing protein. (957 aa)
	PV10_04003	TAF domain-containing protein. (447 aa)
	PV10_03751	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (112 aa)
	PV10_03389	CBFD_NFYB_HMF domain-containing protein. (359 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A52_06028	B0A52_07467	A0A0D2AFF2	A0A0D2A8F2	TATA-box-binding protein, variant.	TFIIB-type domain-containing protein.	0.999
B0A52_06028	PV10_00205	A0A0D2AFF2	A0A0D2ABM1	TATA-box-binding protein, variant.	TAF8_C domain-containing protein.	0.995
B0A52_06028	PV10_00388	A0A0D2AFF2	A0A0D1Y777	TATA-box-binding protein, variant.	Uncharacterized protein.	0.863
B0A52_06028	PV10_01196	A0A0D2AFF2	A0A0D1ZU44	TATA-box-binding protein, variant.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.960
B0A52_06028	PV10_01598	A0A0D2AFF2	A0A0D2AG49	TATA-box-binding protein, variant.	TFIIE beta domain-containing protein.	0.951
B0A52_06028	PV10_03389	A0A0D2AFF2	A0A0D1ZP68	TATA-box-binding protein, variant.	CBFD_NFYB_HMF domain-containing protein.	0.985
B0A52_06028	PV10_03751	A0A0D2AFF2	A0A0D1ZF02	TATA-box-binding protein, variant.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.994
B0A52_06028	PV10_04003	A0A0D2AFF2	A0A0D1ZDF2	TATA-box-binding protein, variant.	TAF domain-containing protein.	0.999
B0A52_06028	PV10_04433	A0A0D2AFF2	A0A0D1XY87	TATA-box-binding protein, variant.	DUF3591 domain-containing protein.	0.999
B0A52_07467	B0A52_06028	A0A0D2A8F2	A0A0D2AFF2	TFIIB-type domain-containing protein.	TATA-box-binding protein, variant.	0.999
B0A52_07467	PV10_00205	A0A0D2A8F2	A0A0D2ABM1	TFIIB-type domain-containing protein.	TAF8_C domain-containing protein.	0.892
B0A52_07467	PV10_00388	A0A0D2A8F2	A0A0D1Y777	TFIIB-type domain-containing protein.	Uncharacterized protein.	0.868
B0A52_07467	PV10_01196	A0A0D2A8F2	A0A0D1ZU44	TFIIB-type domain-containing protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.990
B0A52_07467	PV10_01598	A0A0D2A8F2	A0A0D2AG49	TFIIB-type domain-containing protein.	TFIIE beta domain-containing protein.	0.987
B0A52_07467	PV10_03389	A0A0D2A8F2	A0A0D1ZP68	TFIIB-type domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.660
B0A52_07467	PV10_03751	A0A0D2A8F2	A0A0D1ZF02	TFIIB-type domain-containing protein.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.961
B0A52_07467	PV10_04003	A0A0D2A8F2	A0A0D1ZDF2	TFIIB-type domain-containing protein.	TAF domain-containing protein.	0.926
B0A52_07467	PV10_04433	A0A0D2A8F2	A0A0D1XY87	TFIIB-type domain-containing protein.	DUF3591 domain-containing protein.	0.979
B0A52_07467	PV10_07636	A0A0D2A8F2	A0A0D1Z642	TFIIB-type domain-containing protein.	BTB domain-containing protein.	0.972
PV10_00205	B0A52_06028	A0A0D2ABM1	A0A0D2AFF2	TAF8_C domain-containing protein.	TATA-box-binding protein, variant.	0.995