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PV10_06913 PV10_06913 B0A52_01655 B0A52_01655 PV10_05522 PV10_05522 B0A52_02785 B0A52_02785 PV10_07971 PV10_07971 PV10_08535 PV10_08535 PV10_00274 PV10_00274 PV10_00663 PV10_00663 PV10_04830 PV10_04830 PV10_00654 PV10_00654 PV10_01196 PV10_01196 PV10_06588 PV10_06588 PV10_02041 PV10_02041
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PV10_06913CDC73_C domain-containing protein. (446 aa)
B0A52_0165526S protease regulatory subunit 8 A; Belongs to the AAA ATPase family. (389 aa)
PV10_05522Serine/threonine-protein kinase bur1. (690 aa)
B0A52_0278526S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (393 aa)
PV10_07971Cell differentiation protein rcd1. (415 aa)
PV10_08535Uncharacterized protein. (487 aa)
PV10_00274Plus3 domain-containing protein. (606 aa)
PV10_00663Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (706 aa)
PV10_04830Prefoldin, alpha subunit. (201 aa)
PV10_00654Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1427 aa)
PV10_01196Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (705 aa)
PV10_06588Protein kinase domain-containing protein. (1038 aa)
PV10_02041Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (422 aa)
Your Current Organism:
Exophiala mesophila
NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila
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