13 items (Exophiala mesophila) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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Predicted Interactions

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Your Input:
	PV10_06913	CDC73_C domain-containing protein. (446 aa)
	B0A52_01655	26S protease regulatory subunit 8 A; Belongs to the AAA ATPase family. (389 aa)
	PV10_05522	Serine/threonine-protein kinase bur1. (690 aa)
	B0A52_02785	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (393 aa)
	PV10_07971	Cell differentiation protein rcd1. (415 aa)
	PV10_08535	Uncharacterized protein. (487 aa)
	PV10_00274	Plus3 domain-containing protein. (606 aa)
	PV10_00663	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (706 aa)
	PV10_04830	Prefoldin, alpha subunit. (201 aa)
	PV10_00654	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1427 aa)
	PV10_01196	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (705 aa)
	PV10_06588	Protein kinase domain-containing protein. (1038 aa)
	PV10_02041	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (422 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A52_01655	B0A52_02785	A0A0D1WLN0	A0A0D1WYY1	26S protease regulatory subunit 8 A; Belongs to the AAA ATPase family.	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	0.999
B0A52_01655	PV10_00663	A0A0D1WLN0	A0A0D1Y7V8	26S protease regulatory subunit 8 A; Belongs to the AAA ATPase family.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.695
B0A52_02785	B0A52_01655	A0A0D1WYY1	A0A0D1WLN0	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	26S protease regulatory subunit 8 A; Belongs to the AAA ATPase family.	0.999
B0A52_02785	PV10_00663	A0A0D1WYY1	A0A0D1Y7V8	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.644
B0A52_02785	PV10_08535	A0A0D1WYY1	A0A0D1XL37	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.419
PV10_00274	PV10_00654	A0A0D1Y6N2	A0A0D1ZQE5	Plus3 domain-containing protein.	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	0.958
PV10_00274	PV10_00663	A0A0D1Y6N2	A0A0D1Y7V8	Plus3 domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.720
PV10_00274	PV10_05522	A0A0D1Y6N2	A0A0D1WPD8	Plus3 domain-containing protein.	Serine/threonine-protein kinase bur1.	0.485
PV10_00274	PV10_06588	A0A0D1Y6N2	A0A0D1ZZ58	Plus3 domain-containing protein.	Protein kinase domain-containing protein.	0.488
PV10_00274	PV10_06913	A0A0D1Y6N2	A0A0D1WKQ9	Plus3 domain-containing protein.	CDC73_C domain-containing protein.	0.995
PV10_00274	PV10_08535	A0A0D1Y6N2	A0A0D1XL37	Plus3 domain-containing protein.	Uncharacterized protein.	0.999
PV10_00654	PV10_00274	A0A0D1ZQE5	A0A0D1Y6N2	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	Plus3 domain-containing protein.	0.958
PV10_00654	PV10_00663	A0A0D1ZQE5	A0A0D1Y7V8	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.725
PV10_00654	PV10_05522	A0A0D1ZQE5	A0A0D1WPD8	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	Serine/threonine-protein kinase bur1.	0.597
PV10_00654	PV10_06588	A0A0D1ZQE5	A0A0D1ZZ58	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	Protein kinase domain-containing protein.	0.490
PV10_00654	PV10_06913	A0A0D1ZQE5	A0A0D1WKQ9	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	CDC73_C domain-containing protein.	0.960
PV10_00654	PV10_08535	A0A0D1ZQE5	A0A0D1XL37	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	Uncharacterized protein.	0.994
PV10_00663	B0A52_01655	A0A0D1Y7V8	A0A0D1WLN0	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	26S protease regulatory subunit 8 A; Belongs to the AAA ATPase family.	0.695
PV10_00663	B0A52_02785	A0A0D1Y7V8	A0A0D1WYY1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	0.644
PV10_00663	PV10_00274	A0A0D1Y7V8	A0A0D1Y6N2	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Plus3 domain-containing protein.	0.720