(16 nodes) Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway network (Exophiala mesophila)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	PV10_08363	E3 ubiquitin-protein ligase. (808 aa)
	PV10_08467	Uncharacterized protein. (188 aa)
	PV10_06975	GLUE N-terminal domain-containing protein. (611 aa)
	PV10_07273	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (255 aa)
	PV10_04597	Uncharacterized protein. (288 aa)
	PV10_04882	Uncharacterized protein. (225 aa)
	PV10_02666	Uncharacterized protein. (878 aa)
	PV10_00036	MPN domain-containing protein. (492 aa)
	PV10_03535	Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (245 aa)
	PV10_00656	Uncharacterized protein. (659 aa)
	PV10_00955	Uncharacterized protein. (637 aa)
	PV10_03170	USP domain-containing protein; Belongs to the peptidase C19 family. (1346 aa)
	PV10_08097	Uncharacterized protein. (217 aa)
	B0A52_01973	DOA4-independent degradation protein 4. (221 aa)
	PV10_04550	RING-type domain-containing protein. (781 aa)
	PV10_00715	Uncharacterized protein. (219 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A52_01973	PV10_00036	A0A0D1WW08	A0A0D1ZND1	DOA4-independent degradation protein 4.	MPN domain-containing protein.	0.800
B0A52_01973	PV10_00715	A0A0D1WW08	A0A0D1Y839	DOA4-independent degradation protein 4.	Uncharacterized protein.	0.999
B0A52_01973	PV10_00955	A0A0D1WW08	A0A0D2AE52	DOA4-independent degradation protein 4.	Uncharacterized protein.	0.844
B0A52_01973	PV10_03535	A0A0D1WW08	A0A0D1ZPS1	DOA4-independent degradation protein 4.	Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.857
B0A52_01973	PV10_04882	A0A0D1WW08	A0A0D1ZG70	DOA4-independent degradation protein 4.	Uncharacterized protein.	0.999
B0A52_01973	PV10_06975	A0A0D1WW08	A0A0D1Z6R9	DOA4-independent degradation protein 4.	GLUE N-terminal domain-containing protein.	0.885
B0A52_01973	PV10_07273	A0A0D1WW08	A0A0D1Z7I9	DOA4-independent degradation protein 4.	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	0.890
B0A52_01973	PV10_08097	A0A0D1WW08	A0A0D1XJN0	DOA4-independent degradation protein 4.	Uncharacterized protein.	0.996
B0A52_01973	PV10_08467	A0A0D1WW08	A0A0D1Z4H6	DOA4-independent degradation protein 4.	Uncharacterized protein.	0.891
PV10_00036	B0A52_01973	A0A0D1ZND1	A0A0D1WW08	MPN domain-containing protein.	DOA4-independent degradation protein 4.	0.800
PV10_00036	PV10_00715	A0A0D1ZND1	A0A0D1Y839	MPN domain-containing protein.	Uncharacterized protein.	0.405
PV10_00036	PV10_04882	A0A0D1ZND1	A0A0D1ZG70	MPN domain-containing protein.	Uncharacterized protein.	0.855
PV10_00036	PV10_08363	A0A0D1ZND1	A0A0D1WIM7	MPN domain-containing protein.	E3 ubiquitin-protein ligase.	0.491
PV10_00656	PV10_08363	A0A0D1ZSE3	A0A0D1WIM7	Uncharacterized protein.	E3 ubiquitin-protein ligase.	0.539
PV10_00715	B0A52_01973	A0A0D1Y839	A0A0D1WW08	Uncharacterized protein.	DOA4-independent degradation protein 4.	0.999
PV10_00715	PV10_00036	A0A0D1Y839	A0A0D1ZND1	Uncharacterized protein.	MPN domain-containing protein.	0.405
PV10_00715	PV10_00955	A0A0D1Y839	A0A0D2AE52	Uncharacterized protein.	Uncharacterized protein.	0.852
PV10_00715	PV10_03535	A0A0D1Y839	A0A0D1ZPS1	Uncharacterized protein.	Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.820
PV10_00715	PV10_04882	A0A0D1Y839	A0A0D1ZG70	Uncharacterized protein.	Uncharacterized protein.	0.999
PV10_00715	PV10_06975	A0A0D1Y839	A0A0D1Z6R9	Uncharacterized protein.	GLUE N-terminal domain-containing protein.	0.927