STRINGSTRING
B0A52_01655 B0A52_01655 B0A52_02785 B0A52_02785 PV10_00398 PV10_00398 PV10_08948 PV10_08948 PV10_06358 PV10_06358 PV10_00663 PV10_00663 PV10_03751 PV10_03751 B0A52_00610 B0A52_00610 B0A52_01899 B0A52_01899 PV10_01365 PV10_01365 PV10_00654 PV10_00654
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
B0A52_0165526S protease regulatory subunit 8 A; Belongs to the AAA ATPase family. (389 aa)
B0A52_0278526S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (393 aa)
PV10_00398PC4 domain-containing protein. (187 aa)
PV10_08948Uncharacterized protein. (1891 aa)
PV10_06358FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (568 aa)
PV10_00663Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (706 aa)
PV10_03751Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (112 aa)
B0A52_0061026S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (422 aa)
B0A52_01899CBFD_NFYB_HMF domain-containing protein. (163 aa)
PV10_0136526S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (466 aa)
PV10_00654Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1427 aa)
Your Current Organism:
Exophiala mesophila
NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila
Server load: low (24%) [HD]