STRINGSTRING
B0A52_03640 B0A52_03640 PV10_08668 PV10_08668 PV10_08793 PV10_08793 PV10_07248 PV10_07248 PV10_05526 PV10_05526 PV10_05871 PV10_05871 PV10_06482 PV10_06482 PV10_03730 PV10_03730 PV10_03752 PV10_03752 PV10_03884 PV10_03884 PV10_04435 PV10_04435 PV10_05059 PV10_05059 MCM7 MCM7 PV10_00216 PV10_00216 PV10_01446 PV10_01446 PV10_01600 PV10_01600 PV10_08324 PV10_08324 PV10_08605 PV10_08605 B0A52_04315 B0A52_04315 PV10_08739 PV10_08739 B0A52_01899 B0A52_01899 PV10_05576 PV10_05576 PV10_05907 PV10_05907 PV10_06115 PV10_06115 PV10_06236 PV10_06236 PV10_06386 PV10_06386 PV10_03866 PV10_03866 PV10_04251 PV10_04251 PV10_04433 PV10_04433 PV10_04578 PV10_04578 PV10_02436 PV10_02436 PV10_03089 PV10_03089 PV10_00663 PV10_00663 PV10_00806 PV10_00806 PV10_01681 PV10_01681 PV10_01821 PV10_01821 PV10_09167 PV10_09167 PV10_08001 PV10_08001 PV10_08510 PV10_08510 PV10_08841 PV10_08841 PV10_08543 PV10_08543 PV10_08755 PV10_08755 PV10_08796 PV10_08796 PV10_06838 PV10_06838 PV10_06985 PV10_06985 B0A52_05764 B0A52_05764 PV10_07129 PV10_07129 PV10_05387 PV10_05387 PV10_06358 PV10_06358 PV10_06251 PV10_06251 PV10_06375 PV10_06375 PV10_04003 PV10_04003 PV10_06514 PV10_06514 PV10_04282 PV10_04282 PV10_03751 PV10_03751 PV10_03883 PV10_03883 PV10_03898 PV10_03898 PV10_04710 PV10_04710 PV10_05216 PV10_05216 PV10_03156 PV10_03156 PV10_03205 PV10_03205 PV10_03389 PV10_03389 PV10_00654 PV10_00654 PV10_00324 PV10_00324 B0A52_00854 B0A52_00854 PV10_06819 PV10_06819 PV10_01045 PV10_01045 PV10_01447 PV10_01447 PV10_01743 PV10_01743 PV10_01377 PV10_01377 PV10_01469 PV10_01469 PV10_01516 PV10_01516 PV10_05849 PV10_05849 PV10_05932 PV10_05932 PV10_06117 PV10_06117 PV10_06755 PV10_06755 B0A52_04834 B0A52_04834 PV10_05032 PV10_05032 PV10_02466 PV10_02466 PV10_02657 PV10_02657 B0A52_07467 B0A52_07467 PV10_00080 PV10_00080 PV10_00432 PV10_00432 PV10_01046 PV10_01046
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
B0A52_03640Uncharacterized protein. (259 aa)
PV10_08668WD_REPEATS_REGION domain-containing protein. (316 aa)
PV10_08793Uncharacterized protein. (309 aa)
PV10_07248AAA domain-containing protein. (1732 aa)
PV10_05526Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (399 aa)
PV10_05871Uncharacterized protein. (215 aa)
PV10_06482HTH TFE/IIEalpha-type domain-containing protein. (487 aa)
PV10_03730Uncharacterized protein. (267 aa)
PV10_03752Uncharacterized protein. (350 aa)
PV10_03884CBFD_NFYB_HMF domain-containing protein. (101 aa)
PV10_04435Peptidylprolyl isomerase. (517 aa)
PV10_05059RNA-dependent RNA polymerase. (1230 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (808 aa)
PV10_00216Uncharacterized protein. (1570 aa)
PV10_01446Stc1 domain-containing protein. (318 aa)
PV10_01600Deacetylase sirtuin-type domain-containing protein. (625 aa)
PV10_08324SANT_DAMP1_like domain-containing protein. (858 aa)
PV10_08605Fungal_trans domain-containing protein. (537 aa)
B0A52_04315DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (350 aa)
PV10_08739Uncharacterized protein. (1665 aa)
B0A52_01899CBFD_NFYB_HMF domain-containing protein. (163 aa)
PV10_05576Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. (303 aa)
PV10_05907Uncharacterized protein. (1860 aa)
PV10_06115Uncharacterized protein. (1674 aa)
PV10_06236Transcription elongation factor S-II, variant. (306 aa)
PV10_06386SHNi-TPR domain-containing protein. (526 aa)
PV10_03866Uncharacterized protein. (647 aa)
PV10_04251DNA helicase; Belongs to the MCM family. (724 aa)
PV10_04433DUF3591 domain-containing protein. (1125 aa)
PV10_04578CULLIN_2 domain-containing protein; Belongs to the cullin family. (896 aa)
PV10_02436WD_REPEATS_REGION domain-containing protein. (726 aa)
PV10_03089YL1_C domain-containing protein. (723 aa)
PV10_00663Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (706 aa)
PV10_00806Uncharacterized protein. (936 aa)
PV10_01681DNA helicase; Belongs to the MCM family. (863 aa)
PV10_01821RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (457 aa)
PV10_09167RECA_2 domain-containing protein. (481 aa)
PV10_08001Uncharacterized protein. (1540 aa)
PV10_08510Deacetylase sirtuin-type domain-containing protein. (617 aa)
PV10_08841Myb_DNA-bind_7 domain-containing protein. (662 aa)
PV10_08543Uncharacterized protein. (386 aa)
PV10_08755Uncharacterized protein. (548 aa)
PV10_08796RNA-dependent RNA polymerase. (1375 aa)
PV10_06838TFIID_20kDa domain-containing protein. (599 aa)
PV10_06985Uncharacterized protein. (360 aa)
B0A52_05764Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
PV10_07129Uncharacterized protein. (1005 aa)
PV10_05387WD_REPEATS_REGION domain-containing protein. (625 aa)
PV10_06358FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (568 aa)
PV10_06251Uncharacterized protein. (436 aa)
PV10_06375TAFII55_N domain-containing protein. (747 aa)
PV10_04003TAF domain-containing protein. (447 aa)
PV10_06514DNA helicase; Belongs to the MCM family. (1004 aa)
PV10_04282TAFII28 domain-containing protein. (348 aa)
PV10_03751Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (112 aa)
PV10_03883Uncharacterized protein. (449 aa)
PV10_03898Uncharacterized protein. (613 aa)
PV10_04710CBFD_NFYB_HMF domain-containing protein. (185 aa)
PV10_05216CENP-T_C domain-containing protein. (498 aa)
PV10_03156H15 domain-containing protein. (233 aa)
PV10_03205Acyl_transf_3 domain-containing protein. (466 aa)
PV10_03389CBFD_NFYB_HMF domain-containing protein. (359 aa)
PV10_00654Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1427 aa)
PV10_00324Protein kinase domain-containing protein. (573 aa)
B0A52_00854Histone H2B; Belongs to the histone H2B family. (140 aa)
PV10_06819RECA_2 domain-containing protein. (564 aa)
PV10_01045Uncharacterized protein. (259 aa)
PV10_01447Uncharacterized protein. (748 aa)
PV10_01743PAPA-1 domain-containing protein. (490 aa)
PV10_01377Uncharacterized protein. (296 aa)
PV10_01469DNA helicase; Belongs to the MCM family. (915 aa)
PV10_01516Uncharacterized protein. (429 aa)
PV10_05849Uncharacterized protein. (1065 aa)
PV10_05932DNA helicase; Belongs to the MCM family. (963 aa)
PV10_06117Uncharacterized protein. (478 aa)
PV10_06755Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (330 aa)
B0A52_04834Histone H2A; Belongs to the histone H2A family. (139 aa)
PV10_05032Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (239 aa)
PV10_02466Cell division control protein; Belongs to the CDC6/cdc18 family. (624 aa)
PV10_02657Uncharacterized protein. (791 aa)
B0A52_07467TFIIB-type domain-containing protein. (361 aa)
PV10_00080Zn(2)-C6 fungal-type domain-containing protein. (615 aa)
PV10_00432Uncharacterized protein; Belongs to the actin family. (474 aa)
PV10_01046Zn(2)-C6 fungal-type domain-containing protein. (648 aa)
Your Current Organism:
Exophiala mesophila
NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.