45 items (Exophiala mesophila) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV10_04759	DUF4211 domain-containing protein. (650 aa)
	PV10_05032	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (239 aa)
	PV10_04069	Uncharacterized protein. (776 aa)
	PV10_06374	BTP domain-containing protein. (236 aa)
	PV10_01931	Uncharacterized protein. (451 aa)
	PV10_01824	Uncharacterized protein. (1197 aa)
	PV10_01196	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (705 aa)
	PV10_01662	Uncharacterized protein. (634 aa)
	PV10_07253	CBFD_NFYB_HMF domain-containing protein. (155 aa)
	PV10_00255	CUE domain-containing protein. (680 aa)
	PV10_00436	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (508 aa)
	PV10_03205	Acyl_transf_3 domain-containing protein. (466 aa)
	PV10_02711	DNA repair helicase rad15. (818 aa)
	PV10_02098	RING-type domain-containing protein. (269 aa)
	PV10_05091	Uncharacterized protein. (448 aa)
	PV10_04035	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (463 aa)
	PV10_02041	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (422 aa)
	PV10_03751	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (112 aa)
	PV10_04282	TAFII28 domain-containing protein. (348 aa)
	PV10_06736	Uncharacterized protein. (846 aa)
	PV10_05871	Uncharacterized protein. (215 aa)
	PV10_06482	HTH TFE/IIEalpha-type domain-containing protein. (487 aa)
	PV10_03730	Uncharacterized protein. (267 aa)
	PV10_03752	Uncharacterized protein. (350 aa)
	PV10_01121	Uncharacterized protein. (373 aa)
	PV10_01675	Uncharacterized protein. (903 aa)
	PV10_05897	CYCLIN domain-containing protein; Belongs to the cyclin family. (403 aa)
	PV10_05972	Uncharacterized protein. (283 aa)
	PV10_06645	Uncharacterized protein. (304 aa)
	PV10_04433	DUF3591 domain-containing protein. (1125 aa)
	PV10_03232	AKAP7_NLS domain-containing protein. (400 aa)
	PV10_00388	Uncharacterized protein. (78 aa)
	PV10_00663	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (706 aa)
	PV10_04003	TAF domain-containing protein. (447 aa)
	PV10_06920	Uncharacterized protein. (1309 aa)
	PV10_08543	Uncharacterized protein. (386 aa)
	PV10_06838	TFIID_20kDa domain-containing protein. (599 aa)
	PV10_05519	CBFD_NFYB_HMF domain-containing protein. (292 aa)
	PV10_06158	Uncharacterized protein. (964 aa)
	PV10_06278	Uncharacterized protein. (1097 aa)
	PV10_06310	BZIP domain-containing protein. (318 aa)
	PV10_01772	Uncharacterized protein. (703 aa)
	PV10_01598	TFIIE beta domain-containing protein. (233 aa)
	PV10_06375	TAFII55_N domain-containing protein. (747 aa)
	PV10_00205	TAF8_C domain-containing protein. (323 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV10_00205	PV10_00436	A0A0D2ABM1	A0A0D1ZPS5	TAF8_C domain-containing protein.	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.620
PV10_00205	PV10_00663	A0A0D2ABM1	A0A0D1Y7V8	TAF8_C domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.701
PV10_00205	PV10_01121	A0A0D2ABM1	A0A0D1X6B2	TAF8_C domain-containing protein.	Uncharacterized protein.	0.870
PV10_00205	PV10_01196	A0A0D2ABM1	A0A0D1ZU44	TAF8_C domain-containing protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.863
PV10_00205	PV10_01598	A0A0D2ABM1	A0A0D2AG49	TAF8_C domain-containing protein.	TFIIE beta domain-containing protein.	0.906
PV10_00205	PV10_01662	A0A0D2ABM1	A0A0D1ZTU8	TAF8_C domain-containing protein.	Uncharacterized protein.	0.620
PV10_00205	PV10_02041	A0A0D2ABM1	A0A0D2A5G3	TAF8_C domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.812
PV10_00205	PV10_02098	A0A0D2ABM1	A0A0D1ZK71	TAF8_C domain-containing protein.	RING-type domain-containing protein.	0.620
PV10_00205	PV10_02711	A0A0D2ABM1	A0A0D1ZKA8	TAF8_C domain-containing protein.	DNA repair helicase rad15.	0.620
PV10_00205	PV10_03205	A0A0D2ABM1	A0A0D1ZNP2	TAF8_C domain-containing protein.	Acyl_transf_3 domain-containing protein.	0.966
PV10_00205	PV10_03730	A0A0D2ABM1	A0A0D1WTA1	TAF8_C domain-containing protein.	Uncharacterized protein.	0.997
PV10_00205	PV10_03751	A0A0D2ABM1	A0A0D1ZF02	TAF8_C domain-containing protein.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.875
PV10_00205	PV10_03752	A0A0D2ABM1	A0A0D1WTC1	TAF8_C domain-containing protein.	Uncharacterized protein.	0.875
PV10_00205	PV10_04003	A0A0D2ABM1	A0A0D1ZDF2	TAF8_C domain-containing protein.	TAF domain-containing protein.	0.999
PV10_00205	PV10_04035	A0A0D2ABM1	A0A0D1ZFY4	TAF8_C domain-containing protein.	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	0.611
PV10_00205	PV10_04069	A0A0D2ABM1	A0A0D2A155	TAF8_C domain-containing protein.	Uncharacterized protein.	0.999
PV10_00205	PV10_04282	A0A0D2ABM1	A0A0D1ZEC8	TAF8_C domain-containing protein.	TAFII28 domain-containing protein.	0.977
PV10_00205	PV10_04433	A0A0D2ABM1	A0A0D1XY87	TAF8_C domain-containing protein.	DUF3591 domain-containing protein.	0.992
PV10_00205	PV10_04759	A0A0D2ABM1	A0A0D1ZFT8	TAF8_C domain-containing protein.	DUF4211 domain-containing protein.	0.937
PV10_00205	PV10_05032	A0A0D2ABM1	A0A0D2A4E2	TAF8_C domain-containing protein.	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...]	0.990