45 items (Exophiala mesophila) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV10_04433	DUF3591 domain-containing protein. (1125 aa)
	PV10_02580	Uncharacterized protein. (621 aa)
	PV10_00274	Plus3 domain-containing protein. (606 aa)
	PV10_01598	TFIIE beta domain-containing protein. (233 aa)
	PV10_00205	TAF8_C domain-containing protein. (323 aa)
	PV10_02041	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (422 aa)
	PV10_05032	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (239 aa)
	PV10_04069	Uncharacterized protein. (776 aa)
	PV10_06374	BTP domain-containing protein. (236 aa)
	PV10_01615	Uncharacterized protein. (372 aa)
	PV10_01196	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (705 aa)
	PV10_01662	Uncharacterized protein. (634 aa)
	PV10_01452	Uncharacterized protein. (523 aa)
	PV10_07024	Uncharacterized protein. (556 aa)
	PV10_00436	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (508 aa)
	PV10_00359	Uncharacterized protein. (422 aa)
	PV10_03205	Acyl_transf_3 domain-containing protein. (466 aa)
	PV10_03006	RNA_pol_L_2 domain-containing protein. (122 aa)
	PV10_04282	TAFII28 domain-containing protein. (348 aa)
	PV10_02098	RING-type domain-containing protein. (269 aa)
	PV10_00388	Uncharacterized protein. (78 aa)
	PV10_05091	Uncharacterized protein. (448 aa)
	PV10_04961	RPOLD domain-containing protein. (337 aa)
	PV10_04035	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (463 aa)
	PV10_04759	DUF4211 domain-containing protein. (650 aa)
	PV10_06736	Uncharacterized protein. (846 aa)
	PV10_03751	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (112 aa)
	PV10_06920	Uncharacterized protein. (1309 aa)
	PV10_08543	Uncharacterized protein. (386 aa)
	PV10_06838	TFIID_20kDa domain-containing protein. (599 aa)
	PV10_06724	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (130 aa)
	PV10_06375	TAFII55_N domain-containing protein. (747 aa)
	PV10_04003	TAF domain-containing protein. (447 aa)
	PV10_05811	Uncharacterized protein. (1242 aa)
	PV10_05897	CYCLIN domain-containing protein; Belongs to the cyclin family. (403 aa)
	PV10_05972	Uncharacterized protein. (283 aa)
	PV10_08668	WD_REPEATS_REGION domain-containing protein. (316 aa)
	PV10_06913	CDC73_C domain-containing protein. (446 aa)
	PV10_05871	Uncharacterized protein. (215 aa)
	PV10_06482	HTH TFE/IIEalpha-type domain-containing protein. (487 aa)
	PV10_03730	Uncharacterized protein. (267 aa)
	PV10_03752	Uncharacterized protein. (350 aa)
	PV10_05212	Uncharacterized protein. (265 aa)
	PV10_01121	Uncharacterized protein. (373 aa)
	PV10_08535	Uncharacterized protein. (487 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV10_00205	PV10_00436	A0A0D2ABM1	A0A0D1ZPS5	TAF8_C domain-containing protein.	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.620
PV10_00205	PV10_01121	A0A0D2ABM1	A0A0D1X6B2	TAF8_C domain-containing protein.	Uncharacterized protein.	0.870
PV10_00205	PV10_01196	A0A0D2ABM1	A0A0D1ZU44	TAF8_C domain-containing protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.863
PV10_00205	PV10_01598	A0A0D2ABM1	A0A0D2AG49	TAF8_C domain-containing protein.	TFIIE beta domain-containing protein.	0.906
PV10_00205	PV10_01662	A0A0D2ABM1	A0A0D1ZTU8	TAF8_C domain-containing protein.	Uncharacterized protein.	0.620
PV10_00205	PV10_02041	A0A0D2ABM1	A0A0D2A5G3	TAF8_C domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.812
PV10_00205	PV10_02098	A0A0D2ABM1	A0A0D1ZK71	TAF8_C domain-containing protein.	RING-type domain-containing protein.	0.620
PV10_00205	PV10_03006	A0A0D2ABM1	A0A0D1ZL15	TAF8_C domain-containing protein.	RNA_pol_L_2 domain-containing protein.	0.812
PV10_00205	PV10_03205	A0A0D2ABM1	A0A0D1ZNP2	TAF8_C domain-containing protein.	Acyl_transf_3 domain-containing protein.	0.966
PV10_00205	PV10_03730	A0A0D2ABM1	A0A0D1WTA1	TAF8_C domain-containing protein.	Uncharacterized protein.	0.997
PV10_00205	PV10_03751	A0A0D2ABM1	A0A0D1ZF02	TAF8_C domain-containing protein.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.875
PV10_00205	PV10_03752	A0A0D2ABM1	A0A0D1WTC1	TAF8_C domain-containing protein.	Uncharacterized protein.	0.875
PV10_00205	PV10_04003	A0A0D2ABM1	A0A0D1ZDF2	TAF8_C domain-containing protein.	TAF domain-containing protein.	0.999
PV10_00205	PV10_04035	A0A0D2ABM1	A0A0D1ZFY4	TAF8_C domain-containing protein.	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	0.611
PV10_00205	PV10_04069	A0A0D2ABM1	A0A0D2A155	TAF8_C domain-containing protein.	Uncharacterized protein.	0.999
PV10_00205	PV10_04282	A0A0D2ABM1	A0A0D1ZEC8	TAF8_C domain-containing protein.	TAFII28 domain-containing protein.	0.977
PV10_00205	PV10_04433	A0A0D2ABM1	A0A0D1XY87	TAF8_C domain-containing protein.	DUF3591 domain-containing protein.	0.992
PV10_00205	PV10_04759	A0A0D2ABM1	A0A0D1ZFT8	TAF8_C domain-containing protein.	DUF4211 domain-containing protein.	0.937
PV10_00205	PV10_04961	A0A0D2ABM1	A0A0D1ZGG2	TAF8_C domain-containing protein.	RPOLD domain-containing protein.	0.864
PV10_00205	PV10_05032	A0A0D2ABM1	A0A0D2A4E2	TAF8_C domain-containing protein.	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...]	0.990