(12 nodes) C2 domain network (Exophiala mesophila)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV10_02465	C2 domain-containing protein. (671 aa)
	PV10_00994	Phosphoinositide phospholipase C. (1136 aa)
	PV10_03514	Uncharacterized protein. (1493 aa)
	PSD2	Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily. (1106 aa)
	PV10_02826	Non-specific serine/threonine protein kinase. (894 aa)
	PV10_00403	Phosphoinositide phospholipase C. (595 aa)
	PV10_03458	Uncharacterized protein. (1372 aa)
	PV10_08363	E3 ubiquitin-protein ligase. (808 aa)
	PV10_00168	C2 domain-containing protein. (935 aa)
	PV10_01831	Uncharacterized protein. (1237 aa)
	PV10_01981	Uncharacterized protein. (1360 aa)
	PV10_05051	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1156 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PSD2	PV10_01831	A0A0D1ZL29	A0A0D1YBV6	Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.	Uncharacterized protein.	0.535
PSD2	PV10_01981	A0A0D1ZL29	A0A0D1ZHU4	Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.	Uncharacterized protein.	0.535
PSD2	PV10_03514	A0A0D1ZL29	A0A0D1ZPN3	Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.	Uncharacterized protein.	0.535
PV10_00403	PV10_05051	A0A0D2ACA9	A0A0D1ZIV8	Phosphoinositide phospholipase C.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.676
PV10_00994	PV10_05051	A0A0D2AE90	A0A0D1ZIV8	Phosphoinositide phospholipase C.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.676
PV10_01831	PSD2	A0A0D1YBV6	A0A0D1ZL29	Uncharacterized protein.	Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.	0.535
PV10_01981	PSD2	A0A0D1ZHU4	A0A0D1ZL29	Uncharacterized protein.	Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.	0.535
PV10_02826	PV10_08363	A0A0D1ZKJ3	A0A0D1WIM7	Non-specific serine/threonine protein kinase.	E3 ubiquitin-protein ligase.	0.682
PV10_03514	PSD2	A0A0D1ZPN3	A0A0D1ZL29	Uncharacterized protein.	Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.	0.535
PV10_05051	PV10_00403	A0A0D1ZIV8	A0A0D2ACA9	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Phosphoinositide phospholipase C.	0.676
PV10_05051	PV10_00994	A0A0D1ZIV8	A0A0D2AE90	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Phosphoinositide phospholipase C.	0.676
PV10_08363	PV10_02826	A0A0D1WIM7	A0A0D1ZKJ3	E3 ubiquitin-protein ligase.	Non-specific serine/threonine protein kinase.	0.682