(52 nodes) Pyridoxal phosphate-dependent transferase, major domain network (Exophiala mesophila)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV10_08770	Aminotran_1_2 domain-containing protein. (365 aa)
	PV10_07694	Uncharacterized protein. (566 aa)
	PV10_05314	Phosphoserine transaminase. (436 aa)
	PV10_05924	Ornithine aminotransferase. (435 aa)
	PV10_06470	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (552 aa)
	PV10_04164	Aminotran_1_2 domain-containing protein. (686 aa)
	PV10_03395	Cysteine desulfurase. (420 aa)
	PV10_03410	Uncharacterized protein. (438 aa)
	PV10_00197	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (477 aa)
	PV10_00704	Aminotran_1_2 domain-containing protein. (508 aa)
	PV10_00956	Uncharacterized protein. (574 aa)
	PV10_01555	Aminotran_5 domain-containing protein. (582 aa)
	PV10_01932	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (498 aa)
	BNA5	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (483 aa)
	PV10_07234	Aspartate aminotransferase. (463 aa)
	PV10_06245	Uncharacterized protein. (535 aa)
	PV10_06382	Uncharacterized protein. (443 aa)
	PV10_03711	Aminotran_1_2 domain-containing protein. (508 aa)
	PV10_04394	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (468 aa)
	PV10_02153	Aminotran_1_2 domain-containing protein. (412 aa)
	hxB	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (819 aa)
	PV10_02876	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (486 aa)
	PV10_01938	Aminotran_1_2 domain-containing protein. (398 aa)
	PV10_08699	Aminotran_5 domain-containing protein. (560 aa)
	PV10_07429	Beta_elim_lyase domain-containing protein. (367 aa)
	PV10_06927	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1078 aa)
	BNA5-2	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (461 aa)
	PV10_07254	Aminotran_1_2 domain-containing protein. (557 aa)
	PV10_05551	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (524 aa)
	PV10_06201	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (448 aa)
	PV10_05730	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (521 aa)
	PV10_05772	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (465 aa)
	PV10_06609	O-acetylhomoserine (Thiol)-lyase. (461 aa)
	PV10_06118	5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (609 aa)
	PV10_03712	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (456 aa)
	PV10_06503	Beta_elim_lyase domain-containing protein. (421 aa)
	PV10_04254	Aminotran_1_2 domain-containing protein. (614 aa)
	PV10_02509	Histidinol-phosphate transaminase. (438 aa)
	PV10_02977	Ornithine aminotransferase. (485 aa)
	PV10_03041	Dethiobiotin synthase. (835 aa)
	PV10_03306	Aminotran_1_2 domain-containing protein. (554 aa)
	PV10_03606	Aminotran_1_2 domain-containing protein. (448 aa)
	PV10_00583	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (529 aa)
	PV10_00260	Uncharacterized protein. (579 aa)
	PV10_00923	Cysteine desulfurase, mitochondrial. (564 aa)
	PV10_00502	Uncharacterized protein. (618 aa)
	PV10_07072	Cystathionine beta-lyase. (464 aa)
	PV10_01324	Aspartate aminotransferase. (427 aa)
	PV10_01829	Aminotran_1_2 domain-containing protein. (483 aa)
	PV10_02051	Aspartate aminotransferase. (424 aa)
	PV10_03015	Uncharacterized protein. (394 aa)
	PV10_03042	Aminotran_1_2 domain-containing protein. (428 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BNA5	PV10_01829	A0A0D1XK93	A0A0D1ZVW6	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Aminotran_1_2 domain-containing protein.	0.786
BNA5	PV10_01938	A0A0D1XK93	A0A0D1YC44	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Aminotran_1_2 domain-containing protein.	0.517
BNA5	PV10_02153	A0A0D1XK93	A0A0D1Y1F2	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Aminotran_1_2 domain-containing protein.	0.517
BNA5	PV10_03306	A0A0D1XK93	A0A0D1ZM15	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Aminotran_1_2 domain-containing protein.	0.490
BNA5	PV10_03606	A0A0D1XK93	A0A0D1ZQ22	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Aminotran_1_2 domain-containing protein.	0.544
BNA5	PV10_03711	A0A0D1XK93	A0A0D1XW06	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Aminotran_1_2 domain-containing protein.	0.634
BNA5	PV10_04254	A0A0D1XK93	A0A0D1ZGX3	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Aminotran_1_2 domain-containing protein.	0.544
BNA5	PV10_04394	A0A0D1XK93	A0A0D1XY46	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.445
BNA5	PV10_07254	A0A0D1XK93	A0A0D1Z7H0	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Aminotran_1_2 domain-containing protein.	0.544
BNA5	PV10_08770	A0A0D1XK93	A0A0D1WJW3	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Aminotran_1_2 domain-containing protein.	0.517
BNA5-2	PV10_01829	A0A0D1Z6V1	A0A0D1ZVW6	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Aminotran_1_2 domain-containing protein.	0.786
BNA5-2	PV10_01938	A0A0D1Z6V1	A0A0D1YC44	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Aminotran_1_2 domain-containing protein.	0.517
BNA5-2	PV10_02153	A0A0D1Z6V1	A0A0D1Y1F2	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Aminotran_1_2 domain-containing protein.	0.517
BNA5-2	PV10_03306	A0A0D1Z6V1	A0A0D1ZM15	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Aminotran_1_2 domain-containing protein.	0.490
BNA5-2	PV10_03606	A0A0D1Z6V1	A0A0D1ZQ22	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Aminotran_1_2 domain-containing protein.	0.544
BNA5-2	PV10_03711	A0A0D1Z6V1	A0A0D1XW06	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Aminotran_1_2 domain-containing protein.	0.634
BNA5-2	PV10_04254	A0A0D1Z6V1	A0A0D1ZGX3	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Aminotran_1_2 domain-containing protein.	0.544
BNA5-2	PV10_04394	A0A0D1Z6V1	A0A0D1XY46	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.445
BNA5-2	PV10_07254	A0A0D1Z6V1	A0A0D1Z7H0	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Aminotran_1_2 domain-containing protein.	0.544
BNA5-2	PV10_08770	A0A0D1Z6V1	A0A0D1WJW3	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Aminotran_1_2 domain-containing protein.	0.517