22 items (Exophiala mesophila) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	PV10_05574	Uncharacterized protein; Belongs to the argonaute family. (1000 aa)
	PV10_05421	Ydc2-catalyt domain-containing protein. (336 aa)
	PV10_05373	Uncharacterized protein. (469 aa)
	PV10_07344	3'-5' exonuclease domain-containing protein. (247 aa)
	PV10_08782	RNase H domain-containing protein. (269 aa)
	PV10_08626	Uncharacterized protein. (780 aa)
	PV10_01004	Uncharacterized protein. (620 aa)
	PV10_00565	HRDC domain-containing protein. (840 aa)
	PV10_03590	Uncharacterized protein. (606 aa)
	PV10_03497	Piwi domain-containing protein. (1065 aa)
	PV10_03031	3'-5' exonuclease domain-containing protein. (147 aa)
	PAN2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1169 aa)
	PV10_04839	Exonuclease domain-containing protein. (317 aa)
	PV10_07087	DNA polymerase. (1453 aa)
	PV10_02579	Exonuclease domain-containing protein. (339 aa)
	PV10_03865	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (338 aa)
	PV10_01310	C2H2-type domain-containing protein. (637 aa)
	PV10_01567	DNA polymerase. (1698 aa)
	PV10_07168	Exonuclease domain-containing protein. (733 aa)
	PV10_07084	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2242 aa)
	PV10_04813	DNA polymerase. (1107 aa)
	PV10_03862	RNase H domain-containing protein. (510 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PAN2	PV10_02579	A0A0D1Y3D7	A0A0D1WZA2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	Exonuclease domain-containing protein.	0.674
PAN2	PV10_03590	A0A0D1Y3D7	A0A0D1Y5V4	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	Uncharacterized protein.	0.442
PAN2	PV10_05373	A0A0D1Y3D7	A0A0D1Z9Q2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	Uncharacterized protein.	0.499
PV10_01310	PV10_02579	A0A0D2AFA4	A0A0D1WZA2	C2H2-type domain-containing protein.	Exonuclease domain-containing protein.	0.913
PV10_01310	PV10_07168	A0A0D2AFA4	A0A0D1ZSI4	C2H2-type domain-containing protein.	Exonuclease domain-containing protein.	0.805
PV10_01567	PV10_03865	A0A0D1ZV56	A0A0D1WTQ2	DNA polymerase.	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.550
PV10_01567	PV10_04813	A0A0D1ZV56	A0A0D1ZG00	DNA polymerase.	DNA polymerase.	0.865
PV10_01567	PV10_07084	A0A0D1ZV56	A0A0D1ZSC2	DNA polymerase.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.881
PV10_01567	PV10_07087	A0A0D1ZV56	A0A0D1XNM2	DNA polymerase.	DNA polymerase.	0.472
PV10_02579	PAN2	A0A0D1WZA2	A0A0D1Y3D7	Exonuclease domain-containing protein.	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	0.674
PV10_02579	PV10_01310	A0A0D1WZA2	A0A0D2AFA4	Exonuclease domain-containing protein.	C2H2-type domain-containing protein.	0.913
PV10_02579	PV10_04839	A0A0D1WZA2	A0A0D1XZF5	Exonuclease domain-containing protein.	Exonuclease domain-containing protein.	0.786
PV10_02579	PV10_07168	A0A0D1WZA2	A0A0D1ZSI4	Exonuclease domain-containing protein.	Exonuclease domain-containing protein.	0.899
PV10_03497	PV10_05373	A0A0D1Y5C9	A0A0D1Z9Q2	Piwi domain-containing protein.	Uncharacterized protein.	0.400
PV10_03590	PAN2	A0A0D1Y5V4	A0A0D1Y3D7	Uncharacterized protein.	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	0.442
PV10_03590	PV10_05373	A0A0D1Y5V4	A0A0D1Z9Q2	Uncharacterized protein.	Uncharacterized protein.	0.409
PV10_03862	PV10_03865	A0A0D1ZFE7	A0A0D1WTQ2	RNase H domain-containing protein.	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.920
PV10_03862	PV10_07084	A0A0D1ZFE7	A0A0D1ZSC2	RNase H domain-containing protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.497
PV10_03865	PV10_01567	A0A0D1WTQ2	A0A0D1ZV56	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	DNA polymerase.	0.550
PV10_03865	PV10_03862	A0A0D1WTQ2	A0A0D1ZFE7	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	RNase H domain-containing protein.	0.920