66 items (Exophiala mesophila) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV10_01726	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria. (885 aa)
	cprA	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (691 aa)
	PV10_05252	GMC_OxRdtase_N domain-containing protein. (611 aa)
	PV10_02915	FAD-binding PCMH-type domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family. (500 aa)
	PV10_00181	Bifunctional cytochrome P450/NADPH--P450 reductase; In the N-terminal section; belongs to the cytochrome P450 family. (1058 aa)
	PV10_08791	Uncharacterized protein. (471 aa)
	PV10_00370	Dihydrolipoyl dehydrogenase. (516 aa)
	PV10_00641	GMC_OxRdtase_N domain-containing protein. (666 aa)
	PV10_01457	Amine oxidase. (493 aa)
	PV10_01652	NADPH:adrenodoxin oxidoreductase, mitochondrial. (524 aa)
	PV10_07617	Amine oxidase. (491 aa)
	PV10_07708	Amine oxidase. (602 aa)
	PV10_05620	Uncharacterized protein. (1105 aa)
	PV10_06518	FAD-binding PCMH-type domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family. (2044 aa)
	PV10_06542	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (311 aa)
	PV10_04415	Amine oxidase. (497 aa)
	PV10_05079	GMC_OxRdtase_N domain-containing protein. (670 aa)
	PV10_03158	Uncharacterized protein. (426 aa)
	COQ6	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (531 aa)
	PV10_03404	Uncharacterized protein. (448 aa)
	PV10_03463	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (507 aa)
	PV10_00645	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (698 aa)
	PV10_00989	Uncharacterized protein. (568 aa)
	PV10_08995	GMC_OxRdtase_N domain-containing protein. (573 aa)
	PV10_08095	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (697 aa)
	PV10_08198	Uncharacterized protein. (440 aa)
	PV10_07932	GMC_OxRdtase_N domain-containing protein. (700 aa)
	B0A52_06985	Isovaleryl-CoA dehydrogenase, mitochondrial. (435 aa)
	PV10_05929	Uncharacterized protein. (454 aa)
	PV10_03769	Uncharacterized protein. (434 aa)
	PV10_04350	Uncharacterized protein. (452 aa)
	PV10_02723	Uncharacterized protein. (404 aa)
	PV10_03114	FAD-binding PCMH-type domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family. (495 aa)
	PV10_03152	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (648 aa)
	PV10_00053	Sulfhydryl oxidase. (206 aa)
	PV10_01728	Uncharacterized protein. (576 aa)
	PV10_01825	Xanthine dehydrogenase. (1359 aa)
	PV10_07202	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (622 aa)
	PV10_07283	Uncharacterized protein. (638 aa)
	PV10_05590	Amine oxidase. (512 aa)
	PV10_05836	FAD-binding FR-type domain-containing protein. (423 aa)
	PV10_06195	Bifunctional cytochrome P450/NADPH--P450 reductase; In the N-terminal section; belongs to the cytochrome P450 family. (1075 aa)
	PV10_06758	GMC_OxRdtase_N domain-containing protein. (605 aa)
	PV10_04413	Amine oxidase. (498 aa)
	PV10_04517	FAD-binding PCMH-type domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family. (618 aa)
	PV10_04866	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (541 aa)
	PV10_05007	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (405 aa)
	PV10_05203	Uncharacterized protein. (535 aa)
	BNA4	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (463 aa)
	PV10_03065	Sulfhydryl oxidase. (218 aa)
	PV10_00680	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (333 aa)
	PV10_01344	Uncharacterized protein. (464 aa)
	PV10_01350	Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (631 aa)
	PV10_01719	GMC_OxRdtase_N domain-containing protein. (559 aa)
	PV10_08744	Thioredoxin reductase. (363 aa)
	PV10_08827	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (312 aa)
	PV10_08391	GMC_OxRdtase_N domain-containing protein. (584 aa)
	PV10_08872	Xanthine dehydrogenase, molybdopterin binding subunit. (1483 aa)
	TAH18	NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of DRE2. Positively controls H(2)O(2)-induced cell death; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (651 aa)
	PV10_07404	Amine oxidase. (487 aa)
	PV10_05688	GMC_OxRdtase_N domain-containing protein. (609 aa)
	PV10_06443	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (697 aa)
	PV10_06051	Amine oxidase. (500 aa)
	PV10_06165	DAO domain-containing protein. (362 aa)
	PV10_03984	DAO domain-containing protein. (354 aa)
	PV10_06580	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (729 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A52_06985	PV10_00370	A0A0D1WPA4	A0A0D1ZRG9	Isovaleryl-CoA dehydrogenase, mitochondrial.	Dihydrolipoyl dehydrogenase.	0.434
B0A52_06985	PV10_00645	A0A0D1WPA4	A0A0D2AD18	Isovaleryl-CoA dehydrogenase, mitochondrial.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.478
B0A52_06985	PV10_01344	A0A0D1WPA4	A0A0D1YAH5	Isovaleryl-CoA dehydrogenase, mitochondrial.	Uncharacterized protein.	0.595
B0A52_06985	PV10_01350	A0A0D1WPA4	A0A0D1YAH6	Isovaleryl-CoA dehydrogenase, mitochondrial.	Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.	0.405
B0A52_06985	PV10_01726	A0A0D1WPA4	A0A0D2AGK6	Isovaleryl-CoA dehydrogenase, mitochondrial.	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	0.794
B0A52_06985	PV10_02723	A0A0D1WPA4	A0A0D1WZV9	Isovaleryl-CoA dehydrogenase, mitochondrial.	Uncharacterized protein.	0.783
B0A52_06985	PV10_03158	A0A0D1WPA4	A0A0D2A998	Isovaleryl-CoA dehydrogenase, mitochondrial.	Uncharacterized protein.	0.638
B0A52_06985	PV10_03404	A0A0D1WPA4	A0A0D2AA11	Isovaleryl-CoA dehydrogenase, mitochondrial.	Uncharacterized protein.	0.618
B0A52_06985	PV10_04350	A0A0D1WPA4	A0A0D1WUY8	Isovaleryl-CoA dehydrogenase, mitochondrial.	Uncharacterized protein.	0.493
B0A52_06985	PV10_04866	A0A0D1WPA4	A0A0D1XZH4	Isovaleryl-CoA dehydrogenase, mitochondrial.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.402
B0A52_06985	PV10_05203	A0A0D1WPA4	A0A0D1Y0P3	Isovaleryl-CoA dehydrogenase, mitochondrial.	Uncharacterized protein.	0.434
B0A52_06985	PV10_05620	A0A0D1WPA4	A0A0D1ZW93	Isovaleryl-CoA dehydrogenase, mitochondrial.	Uncharacterized protein.	0.794
B0A52_06985	PV10_05929	A0A0D1WPA4	A0A0D1WQL1	Isovaleryl-CoA dehydrogenase, mitochondrial.	Uncharacterized protein.	0.800
B0A52_06985	PV10_08095	A0A0D1WPA4	A0A0D1WHW6	Isovaleryl-CoA dehydrogenase, mitochondrial.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.478
B0A52_06985	PV10_08791	A0A0D1WPA4	A0A0D1ZQZ0	Isovaleryl-CoA dehydrogenase, mitochondrial.	Uncharacterized protein.	0.800
BNA4	PV10_01726	A0A0D1Y126	A0A0D2AGK6	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	0.433
BNA4	PV10_05620	A0A0D1Y126	A0A0D1ZW93	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Uncharacterized protein.	0.433
COQ6	PV10_01652	A0A0D2A9C5	A0A0D1ZTT3	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	NADPH:adrenodoxin oxidoreductase, mitochondrial.	0.445
PV10_00053	PV10_01728	A0A0D1X310	A0A0D1X812	Sulfhydryl oxidase.	Uncharacterized protein.	0.427
PV10_00181	PV10_00645	A0A0D1ZQN4	A0A0D2AD18	Bifunctional cytochrome P450/NADPH--P450 reductase; In the N-terminal section; belongs to the cytochrome P450 family.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.448