STRINGSTRING
PV10_00384 PV10_00384 PV10_05906 PV10_05906 PV10_05966 PV10_05966 PV10_03977 PV10_03977 PV10_02271 PV10_02271 PV10_02429 PV10_02429 PV10_00315 PV10_00315 PV10_00418 PV10_00418 PV10_06120 PV10_06120 PV10_03909 PV10_03909 PV10_04042 PV10_04042 PV10_04526 PV10_04526 PV10_04624 PV10_04624 PV10_05065 PV10_05065 PV10_02174 PV10_02174 B0A52_02640 B0A52_02640 PV10_02597 PV10_02597 FEN1 FEN1 PV10_00535 PV10_00535 PV10_00734 PV10_00734 PV10_01851 PV10_01851 PV10_08994 PV10_08994 PV10_08193 PV10_08193 PV10_07701 PV10_07701 PV10_06922 PV10_06922 PV10_07178 PV10_07178 PV10_07259 PV10_07259 PV10_07450 PV10_07450 PV10_07573 PV10_07573 PV10_05530 PV10_05530 PV10_05657 PV10_05657 PV10_05975 PV10_05975 PV10_03733 PV10_03733 PV10_03800 PV10_03800 PV10_04742 PV10_04742 PV10_04318 PV10_04318 PV10_05098 PV10_05098 PV10_03287 PV10_03287 PV10_02952 PV10_02952 PV10_08161 PV10_08161 PV10_00420 PV10_00420 PV10_03569 PV10_03569 B0A52_00628 B0A52_00628 PV10_01023 PV10_01023 PV10_01734 PV10_01734 PV10_01599 PV10_01599 PV10_05475 PV10_05475 PV10_05525 PV10_05525 PV10_04022 PV10_04022 PV10_04931 PV10_04931 PV10_04962 PV10_04962 PV10_02336 PV10_02336 PV10_02814 PV10_02814 PV10_00089 PV10_00089 PV10_00527 PV10_00527 PV10_01080 PV10_01080
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PV10_00384Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (463 aa)
PV10_05906Glutathione synthetase. (548 aa)
PV10_05966Amidophosphoribosyltransferase. (589 aa)
PV10_03977PPM-type phosphatase domain-containing protein. (602 aa)
PV10_02271Pyruvate kinase; Belongs to the pyruvate kinase family. (525 aa)
PV10_02429ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (791 aa)
PV10_00315Isocitrate lyase. (537 aa)
PV10_00418Uncharacterized protein. (581 aa)
PV10_06120Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1548 aa)
PV10_03909Fumarylacetoacetase. (436 aa)
PV10_04042Uncharacterized protein. (584 aa)
PV10_04526Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1573 aa)
PV10_04624S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (392 aa)
PV10_05065Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (714 aa)
PV10_02174Isocitrate lyase. (593 aa)
B0A52_02640Phosphoglucomutase; Belongs to the phosphohexose mutase family. (553 aa)
PV10_02597Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family. (566 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
PV10_00535Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (412 aa)
PV10_00734Inositol-1-monophosphatase. (345 aa)
PV10_01851Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (370 aa)
PV10_08994Fumarylacetoacetase. (436 aa)
PV10_08193Fumarylacetoacetase. (430 aa)
PV10_07701Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (445 aa)
PV10_06922HpcH_HpaI domain-containing protein. (316 aa)
PV10_07178Protein phosphatase; Belongs to the PP2C family. (437 aa)
PV10_07259Inositol-1-monophosphatase. (300 aa)
PV10_07450Fatty acid synthase subunit alpha; Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family. (1866 aa)
PV10_07573Plasma membrane ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. (996 aa)
PV10_05530Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (195 aa)
PV10_05657Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1223 aa)
PV10_05975PPM-type phosphatase domain-containing protein. (456 aa)
PV10_03733tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (317 aa)
PV10_03800Uncharacterized protein. (616 aa)
PV10_04742PPM-type phosphatase domain-containing protein. (520 aa)
PV10_04318Probable acetate kinase. (414 aa)
PV10_05098Fumarylacetoacetase. (426 aa)
PV10_03287Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (997 aa)
PV10_02952Acetolactate synthase. (699 aa)
PV10_08161Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (463 aa)
PV10_00420Uncharacterized protein. (575 aa)
PV10_03569Alkaline phosphatase. (608 aa)
B0A52_00628Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
PV10_01023Uncharacterized protein. (598 aa)
PV10_01734Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1321 aa)
PV10_015993,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (254 aa)
PV10_05475Magnesium transporter. (603 aa)
PV10_05525Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1347 aa)
PV10_04022Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (345 aa)
PV10_04931Protein phosphatase; Belongs to the PP2C family. (502 aa)
PV10_04962Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (684 aa)
PV10_02336Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (526 aa)
PV10_02814Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1357 aa)
PV10_00089Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (427 aa)
PV10_00527Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (403 aa)
PV10_01080Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (607 aa)
Your Current Organism:
Exophiala mesophila
NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila
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