28 items (Exophiala mesophila) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV10_01860	Rhodanese domain-containing protein. (199 aa)
	PV10_07975	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (304 aa)
	PV10_08415	Uncharacterized protein. (358 aa)
	PV10_08429	Hcy-binding domain-containing protein. (331 aa)
	ADI1	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (171 aa)
	PV10_07105	Uncharacterized protein. (464 aa)
	PV10_06281	Adenosylhomocysteinase. (449 aa)
	PV10_04407	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (312 aa)
	PV10_03410	Uncharacterized protein. (438 aa)
	PV10_06382	Uncharacterized protein. (443 aa)
	PV10_03914	Cytochrome b5 heme-binding domain-containing protein. (555 aa)
	PV10_04624	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (392 aa)
	PV10_02188	Uncharacterized protein. (336 aa)
	PV10_00453	Lactamase_B domain-containing protein. (396 aa)
	PV10_08470	Uncharacterized protein. (581 aa)
	PV10_09040	Cysteine dioxygenase. (241 aa)
	PV10_07533	FAD-binding FR-type domain-containing protein. (692 aa)
	PV10_06609	O-acetylhomoserine (Thiol)-lyase. (461 aa)
	PV10_04447	Uncharacterized protein. (576 aa)
	PV10_00454	Pyr_redox_2 domain-containing protein. (596 aa)
	PV10_00061	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (568 aa)
	PV10_01005	Uncharacterized protein. (380 aa)
	PV10_00502	Uncharacterized protein. (618 aa)
	PV10_07072	Cystathionine beta-lyase. (464 aa)
	PV10_01582	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (314 aa)
	PV10_01261	Uncharacterized protein. (286 aa)
	MRI1	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (393 aa)
	PV10_00455	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (237 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADI1	MRI1	A0A0D1WK21	A0A0D2A5A7	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.	0.769
ADI1	PV10_00502	A0A0D1WK21	A0A0D1ZRS9	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Uncharacterized protein.	0.401
ADI1	PV10_03410	A0A0D1WK21	A0A0D1X1Z1	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Uncharacterized protein.	0.401
ADI1	PV10_04407	A0A0D1WK21	A0A0D1WV29	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.631
ADI1	PV10_04624	A0A0D1WK21	A0A0D1XYV3	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.497
ADI1	PV10_06382	A0A0D1WK21	A0A0D1XUK8	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Uncharacterized protein.	0.403
ADI1	PV10_06609	A0A0D1WK21	A0A0D1ZBS0	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	O-acetylhomoserine (Thiol)-lyase.	0.401
ADI1	PV10_07072	A0A0D1WK21	A0A0D1ZSB5	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Cystathionine beta-lyase.	0.403
ADI1	PV10_08429	A0A0D1WK21	A0A0D1WIU3	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Hcy-binding domain-containing protein.	0.714
MRI1	ADI1	A0A0D2A5A7	A0A0D1WK21	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	0.769
MRI1	PV10_04407	A0A0D2A5A7	A0A0D1WV29	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.903
MRI1	PV10_04624	A0A0D2A5A7	A0A0D1XYV3	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.570
MRI1	PV10_08429	A0A0D2A5A7	A0A0D1WIU3	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.	Hcy-binding domain-containing protein.	0.699
PV10_00061	PV10_00454	A0A0D1ZQB5	A0A0D1ZPT9	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	Pyr_redox_2 domain-containing protein.	0.812
PV10_00061	PV10_00502	A0A0D1ZQB5	A0A0D1ZRS9	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	Uncharacterized protein.	0.949
PV10_00061	PV10_01005	A0A0D1ZQB5	A0A0D1ZRJ4	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	Uncharacterized protein.	0.512
PV10_00061	PV10_01261	A0A0D1ZQB5	A0A0D1ZUD3	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	Uncharacterized protein.	0.833
PV10_00061	PV10_01860	A0A0D1ZQB5	A0A0D1ZUH4	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	Rhodanese domain-containing protein.	0.765
PV10_00061	PV10_02188	A0A0D1ZQB5	A0A0D1Y1K0	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	Uncharacterized protein.	0.833
PV10_00061	PV10_03410	A0A0D1ZQB5	A0A0D1X1Z1	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	Uncharacterized protein.	0.948