63 items (Exophiala mesophila) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV10_04760	Uncharacterized protein. (152 aa)
	PV10_08689	BZIP domain-containing protein. (291 aa)
	PV10_07387	AMPK1_CBM domain-containing protein. (274 aa)
	MDM34	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (607 aa)
	PV10_07864	Uncharacterized protein. (153 aa)
	PV10_07904	Uncharacterized protein. (526 aa)
	PV10_05392	Uncharacterized protein. (361 aa)
	B0A52_07298	Ubiquitin-conjugating enzyme E2 13; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
	PV10_05914	Uncharacterized protein. (662 aa)
	PV10_08068	Uncharacterized protein. (134 aa)
	PV10_04471	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2922 aa)
	PV10_04882	Uncharacterized protein. (225 aa)
	PV10_04869	Phosphatidylinositol 3-kinase VPS34. (936 aa)
	PV10_05010	Uncharacterized protein. (433 aa)
	PV10_02455	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (312 aa)
	PV10_02642	ATG11 domain-containing protein. (1393 aa)
	PV10_07952	Non-specific serine/threonine protein kinase. (1065 aa)
	PV10_00392	Uncharacterized protein. (618 aa)
	PV10_00397	Non-specific serine/threonine protein kinase. (912 aa)
	PV10_00074	AMPK1_CBM domain-containing protein. (578 aa)
	B0A52_00659	Ubiquitin-40S ribosomal protein S27a. (154 aa)
	PV10_08688	Zn(2)-C6 fungal-type domain-containing protein. (754 aa)
	PV10_08837	AMPKBI domain-containing protein. (483 aa)
	PV10_01679	Magnesium-dependent phosphatase-1. (259 aa)
	PV10_06009	Autophagy-related protein 3. (371 aa)
	PV10_06471	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. (163 aa)
	PV10_04738	Uncharacterized protein. (641 aa)
	B0A52_01786	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (334 aa)
	PV10_04992	Uncharacterized protein. (172 aa)
	PV10_02432	Protein kinase domain-containing protein. (859 aa)
	PV10_00333	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. (515 aa)
	PV10_08091	UBIQUITIN_CONJUGAT_2 domain-containing protein. (139 aa)
	B0A52_09800	Autophagy-related protein. (118 aa)
	PV10_05374	Uncharacterized protein. (407 aa)
	B0A52_06876	Uncharacterized protein. (54 aa)
	B0A52_06507	Uncharacterized protein. (220 aa)
	PV10_06626	Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily. (936 aa)
	B0A52_07412	DJ-1_PfpI domain-containing protein. (288 aa)
	B0A52_01973	DOA4-independent degradation protein 4. (221 aa)
	PV10_02325	Protein kinase domain-containing protein. (1006 aa)
	PV10_03080	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (741 aa)
	PV10_00447	Uncharacterized protein. (826 aa)
	PV10_01835	Uncharacterized protein. (244 aa)
	PV10_09001	Zn(2)-C6 fungal-type domain-containing protein. (728 aa)
	PV10_09023	Fungal_trans domain-containing protein. (842 aa)
	PV10_09046	Myotubularin phosphatase domain-containing protein. (896 aa)
	PV10_04497	Uncharacterized protein. (517 aa)
	PV10_04741	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (941 aa)
	PV10_03207	Polyubiquitin. (229 aa)
	PV10_00154	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (954 aa)
	PV10_00648	Uncharacterized protein. (219 aa)
	PV10_00658	Uncharacterized protein; Involved in DNA replication and cell separation. Belongs to the SDS23 family. (545 aa)
	PV10_00715	Uncharacterized protein. (219 aa)
	PV10_01591	Zn(2)-C6 fungal-type domain-containing protein. (757 aa)
	PV10_07946	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (272 aa)
	PV10_08687	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (460 aa)
	PV10_08080	Uncharacterized protein. (422 aa)
	PV10_04182	ATG16 domain-containing protein. (207 aa)
	PV10_04120	DJ-1_PfpI domain-containing protein. (278 aa)
	PV10_03812	Uncharacterized protein. (1662 aa)
	PV10_06348	Uncharacterized protein. (175 aa)
	PV10_07644	TPR_REGION domain-containing protein. (649 aa)
	PV10_08097	Uncharacterized protein. (217 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A52_00659	B0A52_01973	A0A0D1ZQI9	A0A0D1WW08	Ubiquitin-40S ribosomal protein S27a.	DOA4-independent degradation protein 4.	0.667
B0A52_00659	B0A52_07298	A0A0D1ZQI9	A0A0D1ZB41	Ubiquitin-40S ribosomal protein S27a.	Ubiquitin-conjugating enzyme E2 13; Belongs to the ubiquitin-conjugating enzyme family.	0.957
B0A52_00659	B0A52_07412	A0A0D1ZQI9	A0A0D1WSZ7	Ubiquitin-40S ribosomal protein S27a.	DJ-1_PfpI domain-containing protein.	0.654
B0A52_00659	B0A52_09800	A0A0D1ZQI9	A0A0D1WJD1	Ubiquitin-40S ribosomal protein S27a.	Autophagy-related protein.	0.720
B0A52_00659	PV10_00447	A0A0D1ZQI9	A0A0D1X4B0	Ubiquitin-40S ribosomal protein S27a.	Uncharacterized protein.	0.851
B0A52_00659	PV10_00715	A0A0D1ZQI9	A0A0D1Y839	Ubiquitin-40S ribosomal protein S27a.	Uncharacterized protein.	0.686
B0A52_00659	PV10_01835	A0A0D1ZQI9	A0A0D1X860	Ubiquitin-40S ribosomal protein S27a.	Uncharacterized protein.	0.666
B0A52_00659	PV10_02642	A0A0D1ZQI9	A0A0D1ZJZ0	Ubiquitin-40S ribosomal protein S27a.	ATG11 domain-containing protein.	0.470
B0A52_00659	PV10_03080	A0A0D1ZQI9	A0A0D1X0W2	Ubiquitin-40S ribosomal protein S27a.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	0.772
B0A52_00659	PV10_03207	A0A0D1ZQI9	A0A0D1Y4J0	Ubiquitin-40S ribosomal protein S27a.	Polyubiquitin.	0.969
B0A52_00659	PV10_04120	A0A0D1ZQI9	A0A0D1XX96	Ubiquitin-40S ribosomal protein S27a.	DJ-1_PfpI domain-containing protein.	0.654
B0A52_00659	PV10_04741	A0A0D1ZQI9	A0A0D1XZ90	Ubiquitin-40S ribosomal protein S27a.	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.731
B0A52_00659	PV10_07644	A0A0D1ZQI9	A0A0D1XQF0	Ubiquitin-40S ribosomal protein S27a.	TPR_REGION domain-containing protein.	0.736
B0A52_00659	PV10_08091	A0A0D1ZQI9	A0A0D1XJM7	Ubiquitin-40S ribosomal protein S27a.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.947
B0A52_01786	PV10_01591	A0A0D1Z4M9	A0A0D1YB81	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.	Zn(2)-C6 fungal-type domain-containing protein.	0.846
B0A52_01786	PV10_04741	A0A0D1Z4M9	A0A0D1XZ90	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.523
B0A52_01786	PV10_07946	A0A0D1Z4M9	A0A0D1Z2U0	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.999
B0A52_01786	PV10_08687	A0A0D1Z4M9	A0A0D1Z2U5	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.985
B0A52_01786	PV10_08688	A0A0D1Z4M9	A0A0D1ZQP2	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.	Zn(2)-C6 fungal-type domain-containing protein.	0.846
B0A52_01786	PV10_09001	A0A0D1Z4M9	A0A0D1XIT5	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.	Zn(2)-C6 fungal-type domain-containing protein.	0.846