(5 nodes) Signal transduction by L1 network (Exophiala mesophila)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV10_00655	Protein kinase domain-containing protein. (546 aa)
	PV10_04854	Protein kinase domain-containing protein. (667 aa)
	PV10_09013	Uncharacterized protein. (197 aa)
	PV10_08963	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (493 aa)
	B0A52_00628	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A52_00628	PV10_00655	A0A0D1ZQG4	A0A0D2AD33	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein kinase domain-containing protein.	0.993
B0A52_00628	PV10_04854	A0A0D1ZQG4	A0A0D1ZID9	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein kinase domain-containing protein.	0.894
B0A52_00628	PV10_08963	A0A0D1ZQG4	A0A0D1WKD4	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.866
B0A52_00628	PV10_09013	A0A0D1ZQG4	A0A0D1ZMU7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.733
PV10_00655	B0A52_00628	A0A0D2AD33	A0A0D1ZQG4	Protein kinase domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.993
PV10_00655	PV10_04854	A0A0D2AD33	A0A0D1ZID9	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.808
PV10_00655	PV10_08963	A0A0D2AD33	A0A0D1WKD4	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.658
PV10_00655	PV10_09013	A0A0D2AD33	A0A0D1ZMU7	Protein kinase domain-containing protein.	Uncharacterized protein.	0.579
PV10_04854	B0A52_00628	A0A0D1ZID9	A0A0D1ZQG4	Protein kinase domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.894
PV10_04854	PV10_00655	A0A0D1ZID9	A0A0D2AD33	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.808
PV10_04854	PV10_08963	A0A0D1ZID9	A0A0D1WKD4	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.580
PV10_04854	PV10_09013	A0A0D1ZID9	A0A0D1ZMU7	Protein kinase domain-containing protein.	Uncharacterized protein.	0.579
PV10_08963	B0A52_00628	A0A0D1WKD4	A0A0D1ZQG4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.866
PV10_08963	PV10_00655	A0A0D1WKD4	A0A0D2AD33	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.658
PV10_08963	PV10_04854	A0A0D1WKD4	A0A0D1ZID9	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.580
PV10_08963	PV10_09013	A0A0D1WKD4	A0A0D1ZMU7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.579
PV10_09013	B0A52_00628	A0A0D1ZMU7	A0A0D1ZQG4	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.733
PV10_09013	PV10_00655	A0A0D1ZMU7	A0A0D2AD33	Uncharacterized protein.	Protein kinase domain-containing protein.	0.579
PV10_09013	PV10_04854	A0A0D1ZMU7	A0A0D1ZID9	Uncharacterized protein.	Protein kinase domain-containing protein.	0.579
PV10_09013	PV10_08963	A0A0D1ZMU7	A0A0D1WKD4	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.579