STRINGSTRING
PV10_05073 PV10_05073 SLX1 SLX1 PV10_08081 PV10_08081 PV10_06269 PV10_06269 PV10_00207 PV10_00207 B0A52_04315 B0A52_04315 PV10_05994 PV10_05994 PV10_06521 PV10_06521 PV10_03207 PV10_03207 PV10_09167 PV10_09167 PV10_08689 PV10_08689 PV10_03795 PV10_03795 PV10_02564 PV10_02564 PV10_03098 PV10_03098 PV10_02860 PV10_02860 PV10_03643 PV10_03643 B0A52_00659 B0A52_00659 PV10_06819 PV10_06819 PV10_00814 PV10_00814 PV10_07844 PV10_07844 PV10_05118 PV10_05118 PV10_00249 PV10_00249
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PV10_05073Protein kinase domain-containing protein. (755 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (399 aa)
PV10_08081DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (625 aa)
PV10_06269zf-GRF domain-containing protein. (360 aa)
PV10_00207Rad51 domain-containing protein. (403 aa)
B0A52_04315DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (350 aa)
PV10_05994Protein kinase domain-containing protein. (531 aa)
PV10_06521Uncharacterized protein. (1608 aa)
PV10_03207Polyubiquitin. (229 aa)
PV10_09167RECA_2 domain-containing protein. (481 aa)
PV10_08689BZIP domain-containing protein. (291 aa)
PV10_03795ERCC4 domain-containing protein. (651 aa)
PV10_02564Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (413 aa)
PV10_03098Asparagine-tRNA ligase. (572 aa)
PV10_02860Uncharacterized protein. (746 aa)
PV10_03643Protein kinase domain-containing protein. (527 aa)
B0A52_00659Ubiquitin-40S ribosomal protein S27a. (154 aa)
PV10_06819RECA_2 domain-containing protein. (564 aa)
PV10_00814ERCC4 domain-containing protein. (612 aa)
PV10_07844Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (607 aa)
PV10_05118Uncharacterized protein. (226 aa)
PV10_00249DUF1767 domain-containing protein. (290 aa)
Your Current Organism:
Exophiala mesophila
NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila
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