38 items (Exophiala mesophila) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B0A52_01643	Uncharacterized protein. (152 aa)
	PV10_06358	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (568 aa)
	PV10_06724	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (130 aa)
	PV10_06302	Uncharacterized protein. (556 aa)
	PV10_06736	Uncharacterized protein. (846 aa)
	PV10_04035	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (463 aa)
	PV10_04961	RPOLD domain-containing protein. (337 aa)
	PV10_05091	Uncharacterized protein. (448 aa)
	PV10_02098	RING-type domain-containing protein. (269 aa)
	PV10_02711	DNA repair helicase rad15. (818 aa)
	PV10_08138	Uncharacterized protein. (425 aa)
	PV10_07724	Uncharacterized protein. (839 aa)
	PV10_05522	Serine/threonine-protein kinase bur1. (690 aa)
	PV10_05645	CFEM domain-containing protein. (281 aa)
	PV10_00312	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (856 aa)
	PV10_05897	CYCLIN domain-containing protein; Belongs to the cyclin family. (403 aa)
	PV10_06236	Transcription elongation factor S-II, variant. (306 aa)
	B0A52_02609	S1 domain-containing protein. (169 aa)
	PV10_02041	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (422 aa)
	PV10_04796	Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (106 aa)
	PV10_06588	Protein kinase domain-containing protein. (1038 aa)
	PV10_01196	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (705 aa)
	PV10_01662	Uncharacterized protein. (634 aa)
	PV10_00936	Uncharacterized protein; Belongs to the cyclin family. (424 aa)
	PV10_00436	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (508 aa)
	PV10_03478	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1761 aa)
	PV10_03006	RNA_pol_L_2 domain-containing protein. (122 aa)
	PV10_03929	Uncharacterized protein. (1026 aa)
	PV10_01985	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1083 aa)
	PV10_02612	Uncharacterized protein; Belongs to the cyclin family. (517 aa)
	PV10_03216	Uncharacterized protein. (362 aa)
	PV10_03372	Uncharacterized protein. (973 aa)
	PV10_03603	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1262 aa)
	B0A52_09440	Uncharacterized protein. (238 aa)
	PV10_00388	Uncharacterized protein. (78 aa)
	PV10_01859	Uncharacterized protein. (673 aa)
	B0A52_01817	RPOL4c domain-containing protein. (152 aa)
	PV10_08543	Uncharacterized protein. (386 aa)

Your Current Organism:

Exophiala mesophila

NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A52_01643	B0A52_01817	A0A0D1Z529	A0A0D1Z4K7	Uncharacterized protein.	RPOL4c domain-containing protein.	0.999
B0A52_01643	B0A52_02609	A0A0D1Z529	A0A0D1XUD0	Uncharacterized protein.	S1 domain-containing protein.	0.999
B0A52_01643	B0A52_09440	A0A0D1Z529	A0A0D1ZJS0	Uncharacterized protein.	Uncharacterized protein.	0.999
B0A52_01643	PV10_00312	A0A0D1Z529	A0A0D1X3N9	Uncharacterized protein.	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	0.883
B0A52_01643	PV10_00388	A0A0D1Z529	A0A0D1Y777	Uncharacterized protein.	Uncharacterized protein.	0.862
B0A52_01643	PV10_00436	A0A0D1Z529	A0A0D1ZPS5	Uncharacterized protein.	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.972
B0A52_01643	PV10_00936	A0A0D1Z529	A0A0D1ZTA6	Uncharacterized protein.	Uncharacterized protein; Belongs to the cyclin family.	0.655
B0A52_01643	PV10_01196	A0A0D1Z529	A0A0D1ZU44	Uncharacterized protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.981
B0A52_01643	PV10_01662	A0A0D1Z529	A0A0D1ZTU8	Uncharacterized protein.	Uncharacterized protein.	0.978
B0A52_01643	PV10_01859	A0A0D1Z529	A0A0D1YBX6	Uncharacterized protein.	Uncharacterized protein.	0.655
B0A52_01643	PV10_01985	A0A0D1Z529	A0A0D1Y107	Uncharacterized protein.	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.995
B0A52_01643	PV10_02041	A0A0D1Z529	A0A0D2A5G3	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.874
B0A52_01643	PV10_02098	A0A0D1Z529	A0A0D1ZK71	Uncharacterized protein.	RING-type domain-containing protein.	0.972
B0A52_01643	PV10_02612	A0A0D1Z529	A0A0D1Y2S5	Uncharacterized protein.	Uncharacterized protein; Belongs to the cyclin family.	0.677
B0A52_01643	PV10_02711	A0A0D1Z529	A0A0D1ZKA8	Uncharacterized protein.	DNA repair helicase rad15.	0.975
B0A52_01643	PV10_03006	A0A0D1Z529	A0A0D1ZL15	Uncharacterized protein.	RNA_pol_L_2 domain-containing protein.	0.999
B0A52_01643	PV10_03216	A0A0D1Z529	A0A0D1Y4J9	Uncharacterized protein.	Uncharacterized protein.	0.662
B0A52_01643	PV10_03372	A0A0D1Z529	A0A0D1Y4Z9	Uncharacterized protein.	Uncharacterized protein.	0.931
B0A52_01643	PV10_03478	A0A0D1Z529	A0A0D1ZMK2	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
B0A52_01643	PV10_03603	A0A0D1Z529	A0A0D1Y5W5	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999