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PV10_07984 PV10_07984 PV10_04833 PV10_04833 MCM7 MCM7 PV10_04096 PV10_04096 PV10_04251 PV10_04251 PV10_05121 PV10_05121 PV10_03207 PV10_03207 PV10_01681 PV10_01681 PV10_08689 PV10_08689 PV10_07563 PV10_07563 PV10_06514 PV10_06514 B0A52_00659 B0A52_00659 B0A52_00854 B0A52_00854 PV10_01469 PV10_01469 PV10_05932 PV10_05932 PV10_06044 PV10_06044 PV10_03762 PV10_03762 PV10_02466 PV10_02466
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PV10_07984UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (338 aa)
PV10_04833Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (750 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (808 aa)
PV10_04096Uncharacterized protein. (583 aa)
PV10_04251DNA helicase; Belongs to the MCM family. (724 aa)
PV10_05121Importin subunit alpha; Belongs to the importin alpha family. (552 aa)
PV10_03207Polyubiquitin. (229 aa)
PV10_01681DNA helicase; Belongs to the MCM family. (863 aa)
PV10_08689BZIP domain-containing protein. (291 aa)
PV10_07563ORC_WH_C domain-containing protein. (761 aa)
PV10_06514DNA helicase; Belongs to the MCM family. (1004 aa)
B0A52_00659Ubiquitin-40S ribosomal protein S27a. (154 aa)
B0A52_00854Histone H2B; Belongs to the histone H2B family. (140 aa)
PV10_01469DNA helicase; Belongs to the MCM family. (915 aa)
PV10_05932DNA helicase; Belongs to the MCM family. (963 aa)
PV10_06044Uncharacterized protein. (560 aa)
PV10_03762Uncharacterized protein. (370 aa)
PV10_02466Cell division control protein; Belongs to the CDC6/cdc18 family. (624 aa)
Your Current Organism:
Exophiala mesophila
NCBI taxonomy Id: 212818
Other names: CBS 402.95, E. mesophila
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